Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q098M6 (Q098M6_STIAD) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
Ordered Locus Names:STAUR_6406 EMBL ADO74163.1
ORF Names:STIAU_7769 EMBL EAU68221.1
OrganismStigmatella aurantiaca (strain DW4/3-1) [Complete proteome] [HAMAP] EMBL EAU68221.1
Taxonomic identifier378806 [NCBI]
Taxonomic lineageBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeCystobacteraceaeStigmatella

Protein attributes

Sequence length326 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. SAAS SAAS005905 HAMAP-Rule MF_00047

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. SAAS SAAS005905 HAMAP-Rule MF_00047

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. SAAS SAAS005905 HAMAP-Rule MF_00047

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. SAAS SAAS005905 HAMAP-Rule MF_00047

Subcellular location

Cytoplasm By similarity SAAS SAAS005905 HAMAP-Rule MF_00047.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS005905

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain101 – 297197ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding129 – 18456ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2511Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2641Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2641Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2661Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
Q098M6 [UniParc].

Last modified October 31, 2006. Version 1.
Checksum: 6C384AA8A8CEDB53

FASTA32634,447
        10         20         30         40         50         60 
MGKRVGVLMG GWGEEREVSL KTGEAAVAAL EAEGHTVTRV FAGPGLDRIL RTAELDVAFL 

        70         80         90        100        110        120 
ALHGRMGEDG KVQGLLELLE LPYTGSGVLA SALAMNKPFA KKLFRLHNLP TPQGYRIGRD 

       130        140        150        160        170        180 
ELALLEERHG DLGFPCVVKP ACGGSSLGLA LVREPEALAP AVAEACRYGG EALVERFVRG 

       190        200        210        220        230        240 
REVTVGILGG EVLGSCEIAA PREGFDYEAK YKGGTNYFLP PRLSATRLAN VESLALSAWR 

       250        260        270        280        290        300 
ALGCRGYGRV DLICSEEQND FVLEVNTLPG LTPTSLLPKI AAQRGIGFAQ LVERILGLAT 

       310        320 
RDEAGVAGMP GMASAVQPVS LRAVAG 

« Hide

References

« Hide 'large scale' references
[1]Nierman W.C.
Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: DW4/3-1 EMBL EAU68221.1.
[2]"Evolution of fruiting body formation in Myxococcales: a comparative genomic analysis."
Huntley S., Hamann N., Wegener-Feldbruegge S., Treuner-Lange A., Kube M., Reinhardt R., Klages S., Mueller R., Ronning C.M., Nierman W.C., Sogaard-Andersen L.
Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DW4/3-1.
[3]"Comparative genomic analysis of fruiting body formation in Myxococcales."
Huntley S., Hamann N., Wegener-Feldbrugge S., Treuner-Lange A., Kube M., Reinhardt R., Klages S., Muller R., Ronning C.M., Nierman W.C., Sogaard-Andersen L.
Mol. Biol. Evol. 28:1083-1097(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: DW4/3-1 EMBL ADO74163.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002271 Genomic DNA. Translation: ADO74163.1.
AAMD01000020 Genomic DNA. Translation: EAU68221.1.
RefSeqYP_003955990.1. NC_014623.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADO74163; ADO74163; STAUR_6406.
EAU68221; EAU68221; STIAU_7769.
GeneID9879899.
KEGGsur:STAUR_6406.
PATRIC38551674. VBIStiAur43712_1948.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01921.

Enzyme and pathway databases

BioCycSAUR378806:GCZI-6406-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ098M6_STIAD
AccessionPrimary (citable) accession number: Q098M6
Entry history
Integrated into UniProtKB/TrEMBL: October 31, 2006
Last sequence update: October 31, 2006
Last modified: February 19, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)