Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q098M6

- Q098M6_STIAD

UniProt

Q098M6 - Q098M6_STIAD

Protein

D-alanine--D-alanine ligase

Gene

ddl

Organism
Stigmatella aurantiaca (strain DW4/3-1)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (31 Oct 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Cell wall formation.UniRule annotationSAAS annotation

    Catalytic activityi

    ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi251 – 2511Magnesium or manganese 1UniRule annotation
    Metal bindingi264 – 2641Magnesium or manganese 1UniRule annotation
    Metal bindingi264 – 2641Magnesium or manganese 2UniRule annotation
    Metal bindingi266 – 2661Magnesium or manganese 2UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi129 – 18456ATPUniRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. D-alanine-D-alanine ligase activity Source: UniProtKB-HAMAP
    3. magnesium ion binding Source: UniProtKB-HAMAP
    4. manganese ion binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. peptidoglycan biosynthetic process Source: UniProtKB-HAMAP
    2. regulation of cell shape Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    Cell shape, Cell wall biogenesis/degradationUniRule annotationSAAS annotation, Peptidoglycan synthesisUniRule annotationSAAS annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, MagnesiumUniRule annotationSAAS annotation, ManganeseUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciSAUR378806:GCZI-6406-MONOMER.
    UniPathwayiUPA00219.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    D-alanine--D-alanine ligaseUniRule annotation (EC:6.3.2.4UniRule annotation)
    Alternative name(s):
    D-Ala-D-Ala ligaseUniRule annotation
    D-alanylalanine synthetaseUniRule annotation
    Gene namesi
    Name:ddlUniRule annotation
    Ordered Locus Names:STAUR_6406Imported
    ORF Names:STIAU_7769Imported
    OrganismiStigmatella aurantiaca (strain DW4/3-1)Imported
    Taxonomic identifieri378806 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeCystobacteraceaeStigmatella
    ProteomesiUP000001351: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Structurei

    3D structure databases

    ProteinModelPortaliQ098M6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini101 – 297197ATP-graspUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the D-alanine--D-alanine ligase family.UniRule annotation
    Contains 1 ATP-grasp domain.UniRule annotation
    Contains ATP-grasp domain.SAAS annotation

    Phylogenomic databases

    KOiK01921.

    Family and domain databases

    Gene3Di3.30.1490.20. 1 hit.
    3.30.470.20. 2 hits.
    3.40.50.20. 1 hit.
    HAMAPiMF_00047. Dala_Dala_lig.
    InterProiIPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR000291. D-Ala_lig_Van_CS.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    IPR011127. Dala_Dala_lig_N.
    IPR016185. PreATP-grasp_dom.
    [Graphical view]
    PANTHERiPTHR23132. PTHR23132. 1 hit.
    PfamiPF07478. Dala_Dala_lig_C. 1 hit.
    PF01820. Dala_Dala_lig_N. 2 hits.
    [Graphical view]
    SUPFAMiSSF52440. SSF52440. 1 hit.
    TIGRFAMsiTIGR01205. D_ala_D_alaTIGR. 1 hit.
    PROSITEiPS50975. ATP_GRASP. 1 hit.
    PS00843. DALA_DALA_LIGASE_1. 1 hit.
    PS00844. DALA_DALA_LIGASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q098M6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGKRVGVLMG GWGEEREVSL KTGEAAVAAL EAEGHTVTRV FAGPGLDRIL    50
    RTAELDVAFL ALHGRMGEDG KVQGLLELLE LPYTGSGVLA SALAMNKPFA 100
    KKLFRLHNLP TPQGYRIGRD ELALLEERHG DLGFPCVVKP ACGGSSLGLA 150
    LVREPEALAP AVAEACRYGG EALVERFVRG REVTVGILGG EVLGSCEIAA 200
    PREGFDYEAK YKGGTNYFLP PRLSATRLAN VESLALSAWR ALGCRGYGRV 250
    DLICSEEQND FVLEVNTLPG LTPTSLLPKI AAQRGIGFAQ LVERILGLAT 300
    RDEAGVAGMP GMASAVQPVS LRAVAG 326
    Length:326
    Mass (Da):34,447
    Last modified:October 31, 2006 - v1
    Checksum:i6C384AA8A8CEDB53
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002271 Genomic DNA. Translation: ADO74163.1.
    AAMD01000020 Genomic DNA. Translation: EAU68221.1.
    RefSeqiYP_003955990.1. NC_014623.1.

    Genome annotation databases

    EnsemblBacteriaiADO74163; ADO74163; STAUR_6406.
    EAU68221; EAU68221; STIAU_7769.
    GeneIDi9879899.
    KEGGisur:STAUR_6406.
    PATRICi38551674. VBIStiAur43712_1948.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002271 Genomic DNA. Translation: ADO74163.1 .
    AAMD01000020 Genomic DNA. Translation: EAU68221.1 .
    RefSeqi YP_003955990.1. NC_014623.1.

    3D structure databases

    ProteinModelPortali Q098M6.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADO74163 ; ADO74163 ; STAUR_6406 .
    EAU68221 ; EAU68221 ; STIAU_7769 .
    GeneIDi 9879899.
    KEGGi sur:STAUR_6406.
    PATRICi 38551674. VBIStiAur43712_1948.

    Phylogenomic databases

    KOi K01921.

    Enzyme and pathway databases

    UniPathwayi UPA00219 .
    BioCyci SAUR378806:GCZI-6406-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1490.20. 1 hit.
    3.30.470.20. 2 hits.
    3.40.50.20. 1 hit.
    HAMAPi MF_00047. Dala_Dala_lig.
    InterProi IPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR000291. D-Ala_lig_Van_CS.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    IPR011127. Dala_Dala_lig_N.
    IPR016185. PreATP-grasp_dom.
    [Graphical view ]
    PANTHERi PTHR23132. PTHR23132. 1 hit.
    Pfami PF07478. Dala_Dala_lig_C. 1 hit.
    PF01820. Dala_Dala_lig_N. 2 hits.
    [Graphical view ]
    SUPFAMi SSF52440. SSF52440. 1 hit.
    TIGRFAMsi TIGR01205. D_ala_D_alaTIGR. 1 hit.
    PROSITEi PS50975. ATP_GRASP. 1 hit.
    PS00843. DALA_DALA_LIGASE_1. 1 hit.
    PS00844. DALA_DALA_LIGASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Nierman W.C.
      Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: DW4/3-1Imported.
    2. "Evolution of fruiting body formation in Myxococcales: a comparative genomic analysis."
      Huntley S., Hamann N., Wegener-Feldbruegge S., Treuner-Lange A., Kube M., Reinhardt R., Klages S., Mueller R., Ronning C.M., Nierman W.C., Sogaard-Andersen L.
      Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DW4/3-1Imported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: DW4/3-1Imported.

    Entry informationi

    Entry nameiQ098M6_STIAD
    AccessioniPrimary (citable) accession number: Q098M6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 31, 2006
    Last sequence update: October 31, 2006
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3