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Protein

Putative phospholipid-transporting ATPase C24B11.12c

Gene

SPAC24B11.12c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + H2O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei569 – 56914-aspartylphosphate intermediateBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

ATP-binding, Magnesium, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-SPO-936837. Ion transport by P-type ATPases.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative phospholipid-transporting ATPase C24B11.12c (EC:3.6.3.1)
Gene namesi
ORF Names:SPAC24B11.12c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC24B11.12c.
PomBaseiSPAC24B11.12c.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei109 – 12921HelicalSequence analysisAdd
BLAST
Transmembranei135 – 15521HelicalSequence analysisAdd
BLAST
Transmembranei457 – 47721HelicalSequence analysisAdd
BLAST
Transmembranei501 – 52121HelicalSequence analysisAdd
BLAST
Transmembranei1066 – 108621HelicalSequence analysisAdd
BLAST
Transmembranei1101 – 112121HelicalSequence analysisAdd
BLAST
Transmembranei1151 – 117121HelicalSequence analysisAdd
BLAST
Transmembranei1193 – 121321HelicalSequence analysisAdd
BLAST
Transmembranei1218 – 123821HelicalSequence analysisAdd
BLAST
Transmembranei1260 – 128021HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 14021402Putative phospholipid-transporting ATPase C24B11.12cPRO_0000046239Add
BLAST

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ09891.

Interactioni

Protein-protein interaction databases

BioGridi278059. 27 interactions.
MINTiMINT-4696075.

Structurei

3D structure databases

ProteinModelPortaliQ09891.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000202528.
InParanoidiQ09891.
KOiK01530.
OMAiERAHEYR.
OrthoDBiEOG092C0BQ4.
PhylomeDBiQ09891.

Family and domain databases

Gene3Di2.70.150.10. 3 hits.
3.40.1110.10. 2 hits.
3.40.50.1000. 2 hits.
InterProiIPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR006539. P-type_ATPase_IV.
IPR032631. P-type_ATPase_N.
IPR001757. P_typ_ATPase.
IPR032630. P_typ_ATPase_c.
IPR026871. PLip_transp_ATPase.
[Graphical view]
PANTHERiPTHR24092. PTHR24092. 2 hits.
PTHR24092:SF87. PTHR24092:SF87. 2 hits.
PfamiPF16212. PhoLip_ATPase_C. 1 hit.
PF16209. PhoLip_ATPase_N. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 2 hits.
SSF81660. SSF81660. 2 hits.
TIGRFAMsiTIGR01652. ATPase-Plipid. 1 hit.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q09891-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESVEEKSKQ RRWLPNFKAL RLKVYRLADR LNIPLADAAR VELEEYDGSD
60 70 80 90 100
PQSLRGLQKL PRTLYFGLPL PDSELDDTGE AKRWFPRNKI RTAKYTPIDF
110 120 130 140 150
IPKNIFLQFQ NVANLFFLFL VILQSISIFG EQVNPGLAAV PLIVVVGITA
160 170 180 190 200
VKDAIEDFRR TMLDIHLNNT PTLRLSHYQN PNIRTEYISY FRRFKKRISA
210 220 230 240 250
LFRVFLAKQE EKKRAKRLND AVPLEDMAGS ESRPSYDSIF RESFEAKRSF
260 270 280 290 300
EDSKGKVPLS ALDGTATILQ SRPMDIIDYE AEATGECHFK KTYWKDVRVG
310 320 330 340 350
DFVKVMDNDE IPADIVIINS SDPEGICYIE TKNLDGETNL KMRHALTCGK
360 370 380 390 400
NVVDEASCER CRFWIESEPP HANLYEYNGA CKSFVHSEAG GSDTSQTVSE
410 420 430 440 450
PISLDSMLLR GCVLRNTKWV IGVVVFTGDD TKIMLNSGAP PLKRSRITRN
460 470 480 490 500
LNWNVYLNFI ILFSMCFVCA VVEGIAWRGH SRSSYYFEFG SIGGSPAKDG
510 520 530 540 550
VVTFFTGVIL FQNLVPISLY ISIEIVKTIQ AIFIYFDKDM YYKKLKYACT
560 570 580 590 600
PKSWNISDDL GQVEYIFSDK TGTLTQNVME FKKCTINGVA YGEAFTEAMA
610 620 630 640 650
GMAKREGKDT EELTLQKQSF IERDRMQMIS QMRNMHDNKY LVDDNLTFIS
660 670 680 690 700
SQFVHDLAGK AGEEQSLACY EFFLALALCH SVVADRVGDR IVYKAQSPDE
710 720 730 740 750
AALVGTARDV GFVFLDQRRD IMVTRALGET QRFKLMDTIE FSSARKRMSV
760 770 780 790 800
IVKGPDNRYV LICKGADSII FERLEPNEQV ELRKTTSEHL RIFALEGLRT
810 820 830 840 850
LCIAKRELTE EEYYEWKEKY DIAASAIENR EEQIEEVADL IESHLTLLGG
860 870 880 890 900
TAIEDRLQEG VPDSIALLAQ AGIKLWVLTG DKMETAINIG FSCNLLDAGM
910 920 930 940 950
DMIKFDVDQE VSTPELEVIL ADYLYRYFGL SGSVEELEAA KKDHDTPSGS
960 970 980 990 1000
HALVIDGSVL KRVLDGPMRT KFLLLCKRCK AVLCCRVSPA QKADVVQLVR
1010 1020 1030 1040 1050
ESLEVMTLAI GDGANDVAMI QKADIGVGIV GEEGRAAAMS ADYAIGQFRF
1060 1070 1080 1090 1100
LSKLVLVHGR WDYNRVAEMV NNFFYKSVVW TFTLFWYQIY NNFDANYLFD
1110 1120 1130 1140 1150
YTYVMLFNLI FSSLPVIVMG VYDQDVNADL SLRIPQLYKR GILQLNSARK
1160 1170 1180 1190 1200
IFIGYMLDGF YQSVICFFFS FLVINNVTTA AQNGRDTMAV QDLGVYVAAP
1210 1220 1230 1240 1250
TIMVVDTYVI LNQSNWDVFS IGLWALSCLT FWFWTGVYSQ SLYTYEFYKS
1260 1270 1280 1290 1300
ASRIFRTPNF WAVLCGTIVS CLFPKFLFMT TQKLFWPYDV DIIRESYRTK
1310 1320 1330 1340 1350
RLHELDEEEE IENAEQSPDW ASSTLQVPFN ASSSSLATPK KEPLRLDTNS
1360 1370 1380 1390 1400
LTLTSSMPRS FTPSYTPSFL EGSPVFSDEI LNRGEYMPHR GSISSSEQPL

RP
Length:1,402
Mass (Da):159,356
Last modified:February 1, 1996 - v1
Checksum:iE8495A7598B3020B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAA91777.1.
AB027875 Genomic DNA. Translation: BAA87179.1.
PIRiT38339. S62557.
RefSeqiNP_592849.1. NM_001018250.2.

Genome annotation databases

EnsemblFungiiSPAC24B11.12c.1; SPAC24B11.12c.1:pep; SPAC24B11.12c.
GeneIDi2541560.
KEGGispo:SPAC24B11.12c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAA91777.1.
AB027875 Genomic DNA. Translation: BAA87179.1.
PIRiT38339. S62557.
RefSeqiNP_592849.1. NM_001018250.2.

3D structure databases

ProteinModelPortaliQ09891.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi278059. 27 interactions.
MINTiMINT-4696075.

Proteomic databases

MaxQBiQ09891.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC24B11.12c.1; SPAC24B11.12c.1:pep; SPAC24B11.12c.
GeneIDi2541560.
KEGGispo:SPAC24B11.12c.

Organism-specific databases

EuPathDBiFungiDB:SPAC24B11.12c.
PomBaseiSPAC24B11.12c.

Phylogenomic databases

HOGENOMiHOG000202528.
InParanoidiQ09891.
KOiK01530.
OMAiERAHEYR.
OrthoDBiEOG092C0BQ4.
PhylomeDBiQ09891.

Enzyme and pathway databases

ReactomeiR-SPO-936837. Ion transport by P-type ATPases.

Miscellaneous databases

PROiQ09891.

Family and domain databases

Gene3Di2.70.150.10. 3 hits.
3.40.1110.10. 2 hits.
3.40.50.1000. 2 hits.
InterProiIPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR006539. P-type_ATPase_IV.
IPR032631. P-type_ATPase_N.
IPR001757. P_typ_ATPase.
IPR032630. P_typ_ATPase_c.
IPR026871. PLip_transp_ATPase.
[Graphical view]
PANTHERiPTHR24092. PTHR24092. 2 hits.
PTHR24092:SF87. PTHR24092:SF87. 2 hits.
PfamiPF16212. PhoLip_ATPase_C. 1 hit.
PF16209. PhoLip_ATPase_N. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 2 hits.
SSF81660. SSF81660. 2 hits.
TIGRFAMsiTIGR01652. ATPase-Plipid. 1 hit.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiATCX_SCHPO
AccessioniPrimary (citable) accession number: Q09891
Secondary accession number(s): Q9USC3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: September 7, 2016
This is version 130 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.