Reviewed, UniProtKB/Swiss-Prot Q09870 (RCL1_SCHPO)

Names and origin

Protein names

Recommended name:
    Probable RNA 3'-terminal phosphate cyclase-like protein

Gene names

ORF Names:

SPAC12G12.06c

Organism

Schizosaccharomyces pombe (Fission yeast) [Complete proteome]

Taxonomic identifier

4896 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces

Protein attributes

Sequence length	363 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA By similarity.
Subcellular location	Nucleus › nucleolus By similarity.
Sequence similarities	Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.

Ontologies

Keywords
Biological process	Ribosome biogenesis
Cellular component	Nucleus
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	ribosome biogenesis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	endoplasmic reticulum Inferred from direct assay. Source: GeneDB_SPombe nucleolus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	catalytic activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 363	363	Probable RNA 3'-terminal phosphate cyclase-like protein		PRO_0000156443

Sequences

	Sequence		Length	Mass (Da)
	Q09870-1 [UniParc]. Last modified February 1, 1996. Version 1. Checksum: 4FC3AC613E6017BB	FASTA	363	39,525
	10 20 30 40 50 60 MSTGQLKRFK GCEYLTHRLV LATLSGTPIR VEGIYPDEAD PGVKDYQVSF LRLLEKLTNG 70 80 90 100 110 120 SVIEISYTGT SFIYRPGNII GGRVVHDCPT TKGIGYFLEP ILILCLFAKT PTSLTLTGVT 130 140 150 160 170 180 SSNEDIGVDV LRTSVLPSLQ KRFQVGDELE LRILKRGSAP GGGGEVNFLC PVIKESLPPI 190 200 210 220 230 240 RLSEFGRVFR IRGIASSTRV SPAFANRLVE SARGVLNPFI PDVFIYTDVR RGDECGNSPG 250 260 270 280 290 300 YSITLVAETN KGCSYAAEHC GEAGETPEDV GSFCAKKLLE VIESGGCVDP YTQPSTLTGM 310 320 330 340 350 360 LLSSEDVNTI VVGQLGITSQ LVVFLRDVKA LFNCEYRFKE LESGQVEMSC LGKGYLNVNR RIQ

References

[1]

"The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P. Nature 415:871-880(2002) [PubMed: 11859360] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 38366 / 972.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU329670 Genomic DNA. Translation: CAA91501.1.
PIR	S62537.
RefSeq	NP_592892.1.
3D structure databases
SMR	Q09870. Positions 12-349.
ModBase	Search...
Protein-protein interaction databases
STRING	Q09870.
Genome annotation databases
GeneID	2542936.
KEGG	spo:SPAC12G12.06c.
NMPDR	fig|4896.1.peg.2862.
Organism-specific databases
GeneDB_Spombe	SPAC12G12.06c.
Phylogenomic databases
eggNOG	fuNOG07806.
HOGENOM	HBG381263.
OMA	CPVRKVL.
OrthoDB	EOG9TQNS3.
PhylomeDB	Q09870.
Gene expression databases
ArrayExpress	Q09870.
Family and domain databases
InterPro	IPR000228. RNA3'_term_phos_cycl-like. IPR020719. RNA3'_term_phos_cycl-like_CS. IPR016443. RNA3'_term_phos_cycl-like_euk. IPR013796. RNA3'_term_phos_cycl_insert. IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b. [Graphical view]
Gene3D	G3DSA:3.65.10.20. RNA3'_term_phos_cycl. 1 hit.
PANTHER	PTHR11096. RNA3'_term_phos_cycl. 1 hit.
Pfam	PF01137. RTC. 1 hit. PF05189. RTC_insert. 1 hit. [Graphical view]
PIRSF	PIRSF005378. RNA3'_term_phos_cycl_euk. 1 hit.
TIGRFAMs	TIGR03400. 18S_RNA_Rcl1p. 1 hit.
PROSITE	PS01287. RTC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RCL1_SCHPO

Accession

Primary (citable) accession number: Q09870

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	February 1, 1996
Last modified:	February 9, 2010
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)