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Protein

F-box/WD repeat-containing protein pof11

Gene

pof11

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Has a role in meiosis.1 Publication

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Meiosis

Enzyme and pathway databases

ReactomeiR-SPO-174113. SCF-beta-TrCP mediated degradation of Emi1.
R-SPO-983168. Antigen processing: Ubiquitination & Proteasome degradation.

Names & Taxonomyi

Protein namesi
Recommended name:
F-box/WD repeat-containing protein pof11
Alternative name(s):
Meiotically up-regulated gene 156 protein
Gene namesi
Name:pof11
Synonyms:mug156
ORF Names:SPAC29E6.01, SPAC30.05
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC29E6.01.
PomBaseiSPAC29E6.01. pof11.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: PomBase
  • ubiquitin ligase complex Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 506506F-box/WD repeat-containing protein pof11PRO_0000051138Add
BLAST

Interactioni

Subunit structurei

Interacts with skp1.1 Publication

GO - Molecular functioni

Protein-protein interaction databases

BioGridi278202. 11 interactions.
IntActiQ09855. 1 interaction.
MINTiMINT-4695754.

Structurei

3D structure databases

ProteinModelPortaliQ09855.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini70 – 11647F-boxPROSITE-ProRule annotationAdd
BLAST
Repeati219 – 25638WD 1Add
BLAST
Repeati259 – 29840WD 2Add
BLAST
Repeati301 – 33838WD 3Add
BLAST
Repeati345 – 38642WD 4Add
BLAST
Repeati388 – 42639WD 5Add
BLAST
Repeati427 – 46438WD 6Add
BLAST
Repeati468 – 50538WD 7Add
BLAST

Sequence similaritiesi

Contains 1 F-box domain.PROSITE-ProRule annotation
Contains 7 WD repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

InParanoidiQ09855.
KOiK03362.
OMAiYLTTHEL.
OrthoDBiEOG7X0VRS.
PhylomeDBiQ09855.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR001810. F-box_dom.
IPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF12937. F-box-like. 1 hit.
PF00400. WD40. 6 hits.
[Graphical view]
PRINTSiPR00320. GPROTEINBRPT.
SMARTiSM00256. FBOX. 1 hit.
SM00320. WD40. 8 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 2 hits.
SSF81383. SSF81383. 2 hits.
PROSITEiPS50181. FBOX. 1 hit.
PS00678. WD_REPEATS_1. 3 hits.
PS50082. WD_REPEATS_2. 6 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q09855-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQDDNGKNV VSKVSDLTSC SDFSTSSPVP CLNPLSHENN RIDLIRDLLA
60 70 80 90 100
SLSKEGVVAV YNHVRSLLFT DFTEVFPEEV SLRVFSYLDQ LDLCKCKLMS
110 120 130 140 150
KRWKRLLEDP GIWKALYMQK GWFVNENVLN EFEAWRRTHK FPQPRFENFL
160 170 180 190 200
KQQNIIGPYG TMFLPQQFIF DSNGRPLLNW SYLYKEHAHL DSNWRHGRFL
210 220 230 240 250
VSTFNNPSIR FPADQDFRAT LDSVYCVQYD DEIMVSGSKD RTVSVWDVNS
260 270 280 290 300
RFILYKLYGH SGSVLCLDFC RRRNLLVSGS SDSTIIIWDW QNRRPLKVYF
310 320 330 340 350
GHTDNVLGVV VSENYIISSS RDHTARVWRL DATSPAEACM HVLRGHLASV
360 370 380 390 400
NSVQYSSKTG LIVTASSDRT LRTWDITTGH CIRIIHAHQR GIACAQYNGK
410 420 430 440 450
FIVSGSSDLT IRIFEASSGK LLRMLQGHED LIRTVRFNDE KIVSGGYDGT
460 470 480 490 500
VRIWNFNTGE QHCVLHNSRN SRVFGLQFDH RRIIACTHSS EILVWNFDDG

LDCTFF
Length:506
Mass (Da):58,257
Last modified:August 14, 2001 - v2
Checksum:iCEF34D4EFFBC2E10
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB061694 Genomic DNA. Translation: BAB55543.1.
CU329670 Genomic DNA. Translation: CAB66464.1.
Z66525 Genomic DNA. Translation: CAA91423.1.
PIRiT38502. S62507.
T50211.
RefSeqiNP_594559.1. NM_001019988.2.

Genome annotation databases

EnsemblFungiiSPAC29E6.01.1; SPAC29E6.01.1:pep; SPAC29E6.01.
GeneIDi2541707.
KEGGispo:SPAC29E6.01.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB061694 Genomic DNA. Translation: BAB55543.1.
CU329670 Genomic DNA. Translation: CAB66464.1.
Z66525 Genomic DNA. Translation: CAA91423.1.
PIRiT38502. S62507.
T50211.
RefSeqiNP_594559.1. NM_001019988.2.

3D structure databases

ProteinModelPortaliQ09855.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi278202. 11 interactions.
IntActiQ09855. 1 interaction.
MINTiMINT-4695754.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC29E6.01.1; SPAC29E6.01.1:pep; SPAC29E6.01.
GeneIDi2541707.
KEGGispo:SPAC29E6.01.

Organism-specific databases

EuPathDBiFungiDB:SPAC29E6.01.
PomBaseiSPAC29E6.01. pof11.

Phylogenomic databases

InParanoidiQ09855.
KOiK03362.
OMAiYLTTHEL.
OrthoDBiEOG7X0VRS.
PhylomeDBiQ09855.

Enzyme and pathway databases

ReactomeiR-SPO-174113. SCF-beta-TrCP mediated degradation of Emi1.
R-SPO-983168. Antigen processing: Ubiquitination & Proteasome degradation.

Miscellaneous databases

PROiQ09855.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR001810. F-box_dom.
IPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF12937. F-box-like. 1 hit.
PF00400. WD40. 6 hits.
[Graphical view]
PRINTSiPR00320. GPROTEINBRPT.
SMARTiSM00256. FBOX. 1 hit.
SM00320. WD40. 8 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 2 hits.
SSF81383. SSF81383. 2 hits.
PROSITEiPS50181. FBOX. 1 hit.
PS00678. WD_REPEATS_1. 3 hits.
PS50082. WD_REPEATS_2. 6 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Systematic genome-wide analysis of F-box protein-encoding genes in fission yeast."
    Harrison C.L., Toda T.
    Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  3. "Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint."
    Lehmann A., Katayama S., Harrison C., Dhut S., Kitamura K., McDonald N., Toda T.
    Genes Cells 9:367-382(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH SKP1.
  4. "A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events."
    Martin-Castellanos C., Blanco M., Rozalen A.E., Perez-Hidalgo L., Garcia A.I., Conde F., Mata J., Ellermeier C., Davis L., San-Segundo P., Smith G.R., Moreno S.
    Curr. Biol. 15:2056-2062(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION IN MEIOSIS.
  5. "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
    Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
    Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiPOF11_SCHPO
AccessioniPrimary (citable) accession number: Q09855
Secondary accession number(s): Q9P7V1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: August 14, 2001
Last modified: June 8, 2016
This is version 128 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.