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Protein

Putative endo-1,3(4)-beta-glucanase 2

Gene

eng2

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Endohydrolysis of (1->3)- or (1->4)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolyzed is itself substituted at C-3.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Protein family/group databases

CAZyiGH81. Glycoside Hydrolase Family 81.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative endo-1,3(4)-beta-glucanase 2 (EC:3.2.1.6)
Short name:
Endo-1,3-beta-glucanase 2
Short name:
Endo-1,4-beta-glucanase 2
Alternative name(s):
Laminarinase-2
Gene namesi
Name:eng2
ORF Names:SPAC23D3.10c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
ProteomesiUP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC23D3.10c.
PomBaseiSPAC23D3.10c. eng2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei137 – 15721HelicalSequence AnalysisAdd
BLAST
Transmembranei307 – 32721HelicalSequence AnalysisAdd
BLAST
Transmembranei460 – 48021HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  • ascus epiplasm Source: PomBase
  • integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 706706Putative endo-1,3(4)-beta-glucanase 2PRO_0000215818Add
BLAST

Proteomic databases

MaxQBiQ09850.

Interactioni

Protein-protein interaction databases

BioGridi277982. 10 interactions.
STRINGi4896.SPAC23D3.10c.1.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 81 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG5498.
HOGENOMiHOG000211468.
InParanoidiQ09850.
OMAiVTEEWNA.
OrthoDBiEOG7MSMXB.
PhylomeDBiQ09850.

Family and domain databases

InterProiIPR005200. Endo-beta-glucanase.
[Graphical view]
PfamiPF03639. Glyco_hydro_81. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q09850-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDVLVPIYTG PINPVFPSRA HPSPPLGLTS NLFPIQTNKF YGNLYIGTRH
60 70 80 90 100
NPSWSHPYSV TWLNGSSYYG LAISHIDDSQ RVFGPDPESV PCQYYFNPAG
110 120 130 140 150
LYSIIISARE FASGNLLSLD QSRHFSIQAT LSATTSGSGT IILPIVAGMG
160 170 180 190 200
FVSGYYTNLT PVFNSSILFS SITKINFSRG YKYRIQLTDG KIWFLYAFPT
210 220 230 240 250
SSSSTFNLTL ASNSQLTTST KFTGLIQICK VPNESVNNSY PDTIYDASAG
260 270 280 290 300
VYTTSISLSA QVSGTTGEYW FRFATAGYTN LNPLMFALPH HMQSFGSDTQ
310 320 330 340 350
AYKTGLGLAS TTMGIMFAYA TKTWHLIEKN LPTQVGFLPI PWNGGSNTYS
360 370 380 390 400
PTALAAIRAA CATDINFDVV NASNLDSMYT SGKIVAMYAQ VCLVASRILG
410 420 430 440 450
DSTLTNTGLT KLKQAMARFT TNTQMYPLVY DTTYKGIIST AGYSSPLADY
460 470 480 490 500
GNTYYNDHHF HWGYHIYACA VIGLLDPSWL VNDNIRYVNA LLRDSANPSE
510 520 530 540 550
SDTYFAMFRN FDWFVGHSWA TGIFESGDGK DEESTSEDFN FLYATKLWGM
560 570 580 590 600
VRNDTVLINR ANLMLAVLKN SLNTYIYMTP TTSVQPSQIL GNYVTGITFM
610 620 630 640 650
NKVDYATYFS AEEYCKQGIH MIPTTPISGY LRSPSYVQQD WNAKIAPIIN
660 670 680 690 700
TFSNNWTGIL WSNYAIYDPK TAYNTFAAST FTADKIDNGA SKTWYLAMAA

GMGGSP
Length:706
Mass (Da):77,948
Last modified:February 1, 1996 - v1
Checksum:i7AA4A9BED26C37B6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAA91245.1.
PIRiS62501.
RefSeqiNP_594547.1. NM_001019976.2.

Genome annotation databases

EnsemblFungiiSPAC23D3.10c.1; SPAC23D3.10c.1:pep; SPAC23D3.10c.
GeneIDi2541480.
KEGGispo:SPAC23D3.10c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAA91245.1.
PIRiS62501.
RefSeqiNP_594547.1. NM_001019976.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi277982. 10 interactions.
STRINGi4896.SPAC23D3.10c.1.

Protein family/group databases

CAZyiGH81. Glycoside Hydrolase Family 81.

Proteomic databases

MaxQBiQ09850.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC23D3.10c.1; SPAC23D3.10c.1:pep; SPAC23D3.10c.
GeneIDi2541480.
KEGGispo:SPAC23D3.10c.

Organism-specific databases

EuPathDBiFungiDB:SPAC23D3.10c.
PomBaseiSPAC23D3.10c. eng2.

Phylogenomic databases

eggNOGiCOG5498.
HOGENOMiHOG000211468.
InParanoidiQ09850.
OMAiVTEEWNA.
OrthoDBiEOG7MSMXB.
PhylomeDBiQ09850.

Miscellaneous databases

NextBioi20802579.
PROiQ09850.

Family and domain databases

InterProiIPR005200. Endo-beta-glucanase.
[Graphical view]
PfamiPF03639. Glyco_hydro_81. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.

Entry informationi

Entry nameiENG2_SCHPO
AccessioniPrimary (citable) accession number: Q09850
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: June 24, 2015
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.