Reviewed,
UniProtKB/Swiss-Prot Q09831 (PPK14_SCHPO)
Last modified
November 24, 2009.
Version 65.
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Serine/threonine-protein kinase ppk14 EC=2.7.11.1 | ||||
| Gene names |
| ||||
| Organism | Schizosaccharomyces pombe (Fission yeast) [Complete proteome] | ||||
| Taxonomic identifier | 4896 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces |
Protein attributes
| Sequence length | 566 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Catalytic activity | ATP + a protein = ADP + a phosphoprotein. |
| Sequence similarities | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. KIN82 subfamily. Contains 1 protein kinase domain. |
Ontologies
| Keywords | |
|---|---|
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Kinase Serine/threonine-protein kinase Transferase |
| PTM | Phosphoprotein |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | protein amino acid phosphorylation Inferred from electronic annotation. Source: InterPro |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine kinase activity Ref.2Traceable author statement. Source: GeneDB_SPombe |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 566 | 566 | Serine/threonine-protein kinase ppk14 | PRO_0000086043 | |||||
Regions | |||||||||
| Domain | 195 – 485 | 291 | Protein kinase | ||||||
| Nucleotide binding | 201 – 209 | 9 | ATP By similarity | ||||||
Sites | |||||||||
| Active site | 320 | 1 | Proton acceptor By similarity | ||||||
| Binding site | 224 | 1 | ATP By similarity | ||||||
Amino acid modifications | |||||||||
| Modified residue | 379 | 1 | Phosphothreonine Ref.3 | ||||||
| Modified residue | 381 | 1 | Phosphoserine Ref.3 | ||||||
| Modified residue | 385 | 1 | Phosphothreonine Ref.3 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.  Nurse P.Nature 415:871-880(2002) [PubMed: 11859360] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 38366 / 972. |
| [2] | "Systematic deletion analysis of fission yeast protein kinases." Bimbo A., Jia Y., Poh S.L., Karuturi R.K.M., den Elzen N., Peng X., Zheng L., O'Connell M., Liu E.T., Balasubramanian M.K., Liu J. Eukaryot. Cell 4:799-813(2005) [PubMed: 15821139] [Abstract] Cited for: IDENTIFICATION. |
| [3] | "Phosphoproteome analysis of fission yeast." Wilson-Grady J.T., Villen J., Gygi S.P. J. Proteome Res. 7:1088-1097(2008) [PubMed: 18257517] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-379; SER-381 AND THR-385, MASS SPECTROMETRY. |
Cross-references
Sequence databases | |
|---|---|
| CU329670 Genomic DNA. Translation: CAA91206.1. | |
| PIR | S62482. |
| RefSeq | NP_593065.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 2543432. |
| GenomeReviews | Gene locus ppk14 in contig CU329670_GR. |
| KEGG | spo:SPAC4G8.05. |
| NMPDR | fig|4896.1.peg.3035. |
Organism-specific databases | |
| GeneDB_Spombe | SPAC4G8.05. |
Phylogenomic databases | |
| OMA | PTAHANP. |
| OrthoDB | EOG96T4HN. |
Enzyme and pathway databases | |
| BRENDA | 2.7.11.1. 653. |
Gene expression databases | |
| ArrayExpress | Q09831. |
Family and domain databases | |
| InterPro | IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017442. Se/Thr_prot_kinase-like_dom. IPR008271. Ser/Thr_prot_kinase_AS. IPR002290. Ser/Thr_prot_kinase_dom. [Graphical view] |
| Pfam | PF00069. Pkinase. 1 hit. [Graphical view] |
| SMART | SM00220. S_TKc. 1 hit. [Graphical view] |
| PROSITE | PS00107. PROTEIN_KINASE_ATP. False negative. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | PPK14_SCHPO | ||||||||
| Accession | Primary (citable) accession number: Q09831 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| UniProtKB/Swiss-Prot annotation A primer on UniProtKB/Swiss-Prot annotation |
| Schizosaccharomyces pombe Schizosaccharomyces pombe: entries and gene names |
| SIMILARITY comments Index of protein domains and families |
