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Protein

Serine/threonine-protein kinase ppk14

Gene

ppk14

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei224ATPPROSITE-ProRule annotation1
Active sitei320Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi201 – 209ATPPROSITE-ProRule annotation9

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein kinase ppk14 (EC:2.7.11.1)
Gene namesi
Name:ppk14
ORF Names:SPAC4G8.05
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC4G8.05
PomBaseiSPAC4G8.05 ppk14

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000860431 – 566Serine/threonine-protein kinase ppk14Add BLAST566

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei379Phosphothreonine1 Publication1
Modified residuei381Phosphoserine1 Publication1
Modified residuei385Phosphothreonine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ09831
PaxDbiQ09831
PRIDEiQ09831

PTM databases

iPTMnetiQ09831

Interactioni

Protein-protein interaction databases

BioGridi279852, 110 interactors
STRINGi4896.SPAC4G8.05.1

Structurei

3D structure databases

ProteinModelPortaliQ09831
SMRiQ09831
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini195 – 485Protein kinasePROSITE-ProRule annotationAdd BLAST291

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. KIN82 subfamily.PROSITE-ProRule annotation

Phylogenomic databases

InParanoidiQ09831
KOiK08286
OMAiKDRTSHV
OrthoDBiEOG092C0HH3
PhylomeDBiQ09831

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 2 hits
PROSITEiView protein in PROSITE
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

Q09831-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNELHDGESS EEGRINVEDH LEEAKKDDTG HWKHSGTAKP SKFRAFIRLH
60 70 80 90 100
FKDSRKFAFS RKKEKELTSE DSDAANQSPS GAPESQTEEE SDRKIDGTGS
110 120 130 140 150
SAEGGDGSGT DSISVIKKSF FKSGRKKKDV PKSRNVSRSN GADTSVQREK
160 170 180 190 200
LKDIFSPHGK EKELAHIKKT VATRARTYSS NSIKICDVEV GPSSFEKVFL
210 220 230 240 250
LGKGDVGRVY LVREKKSGKF YAMKVLSKQE MIKRNKSKRA FAEQHILATS
260 270 280 290 300
NHPFIVTLYH SFQSDEYLYL CMEYCMGGEF FRALQRRPGR CLSENEAKFY
310 320 330 340 350
IAEVTAALEY LHLMGFIYRD LKPENILLHE SGHIMLSDFD LSKQSNSAGA
360 370 380 390 400
PTVIQARNAP SAQNAYALDT KSCIADFRTN SFVGTEEYIA PEVIKGCGHT
410 420 430 440 450
SAVDWWTLGI LFYEMLYATT PFKGKNRNMT FSNILHKDVI FPEYADAPSI
460 470 480 490 500
SSLCKNLIRK LLVKDENDRL GSQAGAADVK LHPFFKNVQW ALLRHTEPPI
510 520 530 540 550
IPKLAPIDEK GNPNISHLKE SKSLDITHSP QNTQTVEVPL SNLSGADHGD
560
DPFESFNSVT VHHEWD
Length:566
Mass (Da):63,482
Last modified:February 1, 1996 - v1
Checksum:i3D18B4F84E10AA13
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAA91206.1
PIRiS62482
RefSeqiNP_593065.1, NM_001018463.2

Genome annotation databases

EnsemblFungiiSPAC4G8.05.1; SPAC4G8.05.1:pep; SPAC4G8.05
GeneIDi2543432
KEGGispo:SPAC4G8.05

Similar proteinsi

Entry informationi

Entry nameiPPK14_SCHPO
AccessioniPrimary (citable) accession number: Q09831
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: April 25, 2018
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health