Q09831 (PPK14_SCHPO) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 1, 2013.
Version 91.
History...
Clusters with 
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Serine/threonine-protein kinase ppk14 EC=2.7.11.1 | ||||
| Gene names |
| ||||
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome] | ||||
| Taxonomic identifier | 284812 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces ›  |
Protein attributes
| Sequence length | 566 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Catalytic activity | ATP + a protein = ADP + a phosphoprotein. |
| Sequence similarities | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. KIN82 subfamily. Contains 1 protein kinase domain. |
Ontologies
| Keywords | |
|---|---|
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Kinase Serine/threonine-protein kinase Transferase |
| PTM | Phosphoprotein |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological_process | activation of bipolar cell growth Inferred from mutant phenotype PubMed 20501954. Source: PomBase cellular response to pheromoneInferred from sequence orthology. Source: PomBase signal transductionNon-traceable author statement. Source: PomBase |
| Molecular_function | ATP binding Inferred from sequence model. Source: PomBase protein serine/threonine kinase activityInferred from sequence model. Source: PomBase |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 566 | 566 | Serine/threonine-protein kinase ppk14 | PRO_0000086043 | |||||
Regions | |||||||||
| Domain | 195 – 485 | 291 | Protein kinase | ||||||
| Nucleotide binding | 201 – 209 | 9 | ATP By similarity | ||||||
Sites | |||||||||
| Active site | 320 | 1 | Proton acceptor By similarity | ||||||
| Binding site | 224 | 1 | ATP By similarity | ||||||
Amino acid modifications | |||||||||
| Modified residue | 379 | 1 | Phosphothreonine Ref.3 | ||||||
| Modified residue | 381 | 1 | Phosphoserine Ref.3 | ||||||
| Modified residue | 385 | 1 | Phosphothreonine Ref.3 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.  Nurse P.Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 972 / ATCC 24843. |
| [2] | "Systematic deletion analysis of fission yeast protein kinases." Bimbo A., Jia Y., Poh S.L., Karuturi R.K.M., den Elzen N., Peng X., Zheng L., O'Connell M., Liu E.T., Balasubramanian M.K., Liu J. Eukaryot. Cell 4:799-813(2005) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION. |
| [3] | "Phosphoproteome analysis of fission yeast." Wilson-Grady J.T., Villen J., Gygi S.P. J. Proteome Res. 7:1088-1097(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-379; SER-381 AND THR-385, MASS SPECTROMETRY. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CU329670 Genomic DNA. Translation: CAA91206.1. |
| PIR | S62482. |
| RefSeq | NP_593065.1. NM_001018463.2. |
3D structure databases | |
| ProteinModelPortal | Q09831. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblFungi | SPAC4G8.05.1; SPAC4G8.05.1:pep; SPAC4G8.05. |
| GeneID | 2543432. |
| KEGG | spo:SPAC4G8.05. |
Organism-specific databases | |
| PomBase | SPAC4G8.05. |
Phylogenomic databases | |
| eggNOG | COG0515. |
| KO | K08286. |
| OMA | HESGHIM. |
| OrthoDB | EOG49PF6Z. |
Family and domain databases | |
| InterPro | IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR002290. Ser/Thr_dual-sp_kinase_dom. IPR008271. Ser/Thr_kinase_AS. [Graphical view] |
| Pfam | PF00069. Pkinase. 1 hit. [Graphical view] |
| SMART | SM00220. S_TKc. 1 hit. [Graphical view] |
| SUPFAM | SSF56112. Kinase_like. 1 hit. |
| PROSITE | PS00107. PROTEIN_KINASE_ATP. False negative. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other | |
| NextBio | 20804445. |
Entry information
| Entry name | PPK14_SCHPO | ||||||||
| Accession | Primary (citable) accession number: Q09831 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Fungal Protein Annotation Program | ||||||||
Relevant documents
| Schizosaccharomyces pombe Schizosaccharomyces pombe: entries and gene names |
| SIMILARITY comments Index of protein domains and families |