Q09780 (KIME_SCHPO) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 29, 2013.
Version 99.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Putative mevalonate kinase Short name=MK EC=2.7.1.36 | ||||
| Gene names |
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| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome] | ||||
| Taxonomic identifier | 284812 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › ![]() |
Protein attributes
| Sequence length | 404 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Function | May contribute to the regulation of the isoprenoid and sterol pathway in living cells By similarity. |
| Catalytic activity | ATP + (R)-mevalonate = ADP + (R)-5-phosphomevalonate. |
| Subcellular location | |
| Sequence similarities | Belongs to the GHMP kinase family. Mevalonate kinase subfamily. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Lipid biosynthesis Lipid metabolism Steroid biosynthesis Steroid metabolism Sterol biosynthesis Sterol metabolism |
| Cellular component | Cytoplasm Nucleus |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Kinase Transferase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological_process | ergosterol biosynthetic process Inferred from sequence or structural similarity. Source: PomBase isoprenoid biosynthetic processInferred from electronic annotation. Source: InterPro |
| Cellular_component | cytosol Inferred from direct assay Ref.3. Source: PomBase nucleusInferred from direct assay Ref.3. Source: PomBase |
| Molecular_function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW mevalonate kinase activityInferred from sequence or structural similarity. Source: PomBase protein homodimerization activityInferred from sequence or structural similarity. Source: PomBase |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AB000541 mRNA. Translation: BAA25169.1. CU329670 Genomic DNA. Translation: CAA91104.1. |
| PIR | S62440. |
| RefSeq | NP_592837.1. NM_001018238.2. |
3D structure databases | |
| ProteinModelPortal | Q09780. |
| ModBase | Search... |
Protein-protein interaction databases | |
| MINT | MINT-4695029. |
| STRING | 4896.SPAC13G6.11c-1. |
Proteomic databases | |
| PaxDb | Q09780. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblFungi | SPAC13G6.11c.1; SPAC13G6.11c.1:pep; SPAC13G6.11c. |
| GeneID | 2542818. |
| KEGG | spo:SPAC13G6.11c. |
Organism-specific databases | |
| PomBase | SPAC13G6.11c. |
Phylogenomic databases | |
| eggNOG | COG1577. |
| HOGENOM | HOG000188934. |
| KO | K00869. |
| OMA | ISCTCEK. |
| OrthoDB | EOG4WHCVG. |
Family and domain databases | |
| Gene3D | 3.30.230.10. 1 hit. |
| InterPro | IPR013750. GHMP_kinase_C_dom. IPR006204. GHMP_kinase_N_dom. IPR006203. GHMP_knse_ATP-bd_CS. IPR006205. Mev_gal_kin. IPR006206. Mevalonate/galactokinase. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. [Graphical view] |
| PANTHER | PTHR10457:SF4. PTHR10457:SF4. 1 hit. |
| Pfam | PF08544. GHMP_kinases_C. 1 hit. PF00288. GHMP_kinases_N. 1 hit. [Graphical view] |
| PRINTS | PR00959. MEVGALKINASE. |
| SUPFAM | SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit. |
| TIGRFAMs | TIGR00549. mevalon_kin. 1 hit. |
| PROSITE | PS00627. GHMP_KINASES_ATP. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other | |
| NextBio | 20803860. |
Entry information
| Entry name | KIME_SCHPO | ||||||||
| Accession | Primary (citable) accession number: Q09780 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Fungal Protein Annotation Program | ||||||||
Relevant documents
| Schizosaccharomyces pombe Schizosaccharomyces pombe: entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with
