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Q09712 (GPI18_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
GPI mannosyltransferase 2
EC=2.4.1.-
Alternative name(s):
GPI mannosyltransferase II
Short name=GPI-MT-II
Glycosylphosphatidylinositol-anchor biosynthesis protein 18
Gene names
Name:gpi18
ORF Names:SPAC18B11.05
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces

Protein attributes

Sequence length426 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly By similarity.

Pathway

Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.

Subcellular location

Endoplasmic reticulum membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the PIGV family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 426426GPI mannosyltransferase 2
PRO_0000116387

Regions

Transmembrane33 – 5321Helical; Potential
Transmembrane129 – 14921Helical; Potential
Transmembrane167 – 18923Helical; Potential
Transmembrane223 – 24321Helical; Potential
Transmembrane252 – 27120Helical; Potential
Transmembrane319 – 33921Helical; Potential
Transmembrane351 – 37121Helical; Potential
Transmembrane403 – 42321Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q09712 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: CAACF57FFAD4E0FC

FASTA42648,825
        10         20         30         40         50         60 
MKLNESAMKN AEKKSNSYLA IRMTRSGYNY FKGICVCTFL LSTILYLGIA VIMSHLCVFD 

        70         80         90        100        110        120 
DTAMLYLRQN RSRLAESNIF RTLFISWIRW DAIYFVDMAV NGSLFEQEWA FSSLWPKIIS 

       130        140        150        160        170        180 
FLAFRSKDVV LLGIVSCFAS IFFHAIACYA LYLLTKSIFS NQKMTAYTVI FYCFSPSGIY 

       190        200        210        220        230        240 
MSVGYTESLF AAFSFLGLLL FIKKQQYPAA FLWSLATLIR SNGIFWCIFF GMPAIGTLKI 

       250        260        270        280        290        300 
SLERLQLTFM QVSQLVGYGT KCLIILVPFF YNQYLGFKLF CPGVAWCNKS LPLIYPAVQE 

       310        320        330        340        350        360 
KYWNVGFLRY WTLNNIPNFL FALLSIIPIL FALFYSISGS TLHSFRSIKS HLVLSALYLY 

       370        380        390        400        410        420 
IGCFHMHTQV LNRMSSALPL LYWSMAHATL YAKSRNLKAF GHCILFVWIV YTVIQAGLYG 


SFLPPA

« Hide

References

[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed: 11859360] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CU329670 Genomic DNA. Translation: CAA90590.1.
PIRS58304. T37909.
RefSeqNP_592878.1. NM_001018278.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ09712.

Protein family/group databases

CAZyGT76. Glycosyltransferase Family 76.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2542588.
GenomeReviewsGene locus gpi18 in contig CU329670_GR.
KEGGspo:SPAC18B11.05.
NMPDRfig|4896.1.peg.2848.

Organism-specific databases

GeneDB_SpombeSPAC18B11.05.

Phylogenomic databases

eggNOGfuNOG08000.
GeneTreeEFGT00050000006849.
OMANIPNFLF.
OrthoDBEOG4PVS82.

Enzyme and pathway databases

BioCycSPOM-XXX-01:SPOM-XXX-01-000612-MONOMER.

Gene expression databases

ArrayExpressQ09712.

Family and domain databases

InterProIPR007315. GPI_Mannosyltransferase_2-like.
[Graphical view]
KOK07542.
PANTHERPTHR12468. Mannosyl_trans2. 1 hit.
PfamPF04188. Mannosyl_trans2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGPI18_SCHPO
AccessionPrimary (citable) accession number: Q09712
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: December 14, 2011
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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