SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q09690

- POM1_SCHPO

UniProt

Q09690 - POM1_SCHPO

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Dual specificity protein kinase pom1

Gene
pom1, SPAC2F7.03c
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Involved in localization of polarized growth and cytokinesis. May interact with both the actin and microtubule cytoskeleton. Requires tea1 for localization to the cell ends but not to the cell center.2 Publications

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei728 – 7281ATP By similarity
Active sitei825 – 8251Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi705 – 7139ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. protein binding Source: IntAct
  3. protein serine/threonine/tyrosine kinase activity Source: UniProtKB-EC
  4. protein serine/threonine kinase activity Source: PomBase

GO - Biological processi

  1. actin filament bundle distribution Source: PomBase
  2. activation of bipolar cell growth Source: PomBase
  3. cell morphogenesis involved in conjugation with cellular fusion Source: PomBase
  4. cellular protein localization Source: PomBase
  5. negative regulation of establishment of actomyosin contractile ring localization Source: PomBase
  6. negative regulation of G2/M transition of mitotic cell cycle Source: PomBase
  7. protein localization to medial cortex Source: PomBase
  8. protein localization to nucleus Source: PomBase
  9. protein phosphorylation Source: PomBase
  10. regulation of actomyosin contractile ring localization Source: PomBase
  11. regulation of cell size Source: PomBase
  12. regulation of establishment or maintenance of cell polarity regulating cell shape Source: PomBase
  13. signal transduction Source: PomBase
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Dual specificity protein kinase pom1 (EC:2.7.12.1)
Gene namesi
Name:pom1
ORF Names:SPAC2F7.03c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
ProteomesiUP000002485: Chromosome I

Organism-specific databases

PomBaseiSPAC2F7.03c.

Subcellular locationi

Cell tip. Cell septum
Note: Present at both poles of the cell throughout the cell cycle irrespective of whether the tips are growing or not. Localized to the septum at the time of cytokinesis.1 Publication

GO - Cellular componenti

  1. cell cortex of cell tip Source: PomBase
  2. cell division site Source: PomBase
  3. cell septum Source: UniProtKB-SubCell
  4. cell tip Source: PomBase
  5. non-growing cell tip Source: PomBase
  6. site of polarized growth Source: PomBase
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10871087Dual specificity protein kinase pom1PRO_0000086579Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei513 – 5131Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ09690.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
tea4O601325EBI-4319163,EBI-1099982

Protein-protein interaction databases

BioGridi278379. 193 interactions.
DIPiDIP-59764N.
IntActiQ09690. 3 interactions.
MINTiMINT-4694097.
STRINGi4896.SPAC2F7.03c-1.

Structurei

3D structure databases

ProteinModelPortaliQ09690.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini699 – 995297Protein kinaseAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi62 – 654Poly-Ser

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0515.
KOiK08825.
OMAiWIRDISS.
OrthoDBiEOG7WDNBB.
PhylomeDBiQ09690.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q09690-1 [UniParc]FASTAAdd to Basket

« Hide

MGYLQSQKAV SLGDENTDAL FKLHTSNRKS ANMFGIKSEL LNPSELSAVG     50
SYSNDICPNR QSSSSTAADT SPSTNASNTN ISFPEQEHKD ELFMNVEPKG 100
VGSSMDNHAI TIHHSTGNGL LRSSFDHDYR QKNSPRNSIH RLSNISIGNN 150
PIDFESSQQN NPSSLNTSSH HRTSSISNSK SFGTSLSYYN RSSKPSDWNQ 200
QNNGGHLSGV ISITQDVSSV PLQSSVFSSG NHAYHASMAP KRSGSWRHTN 250
FHSTSHPRAA SIGNKSGIPP VPTIPPNIGH STDHQHPKAN ISGSLTKSSS 300
ESKNLSTIQS PLKTSNSFFK ELSPHSQITL SNVKNNHSHV GSQTKSHSFA 350
TPSVFDNNKP VSSDNHNNTT TSSQVHPDSR NPDPKAAPKA VSQKTNVDGH 400
RNHEAKHGNT VQNESKSQKS SNKEGRSSRG GFFSRLSFSR SSSRMKKGSK 450
AKHEDAPDVP AIPHAYIADS STKSSYRNGK KTPTRTKSRM QQFINWFKPS 500
KERSSNGNSD SASPPPVPRL SITRSQVSRE PEKPEEIPSV PPLPSNFKDK 550
GHVPQQRSVS YTPKRSSDTS ESLQPSLSFA SSNVLSEPFD RKVADLAMKA 600
INSKRINKLL DDAKVMQSLL DRACIITPVR NTEVQLINTA PLTEYEQDEI 650
NNYDNIYFTG LRNVDKRRSA DENTSSNFGF DDERGDYKVV LGDHIAYRYE 700
VVDFLGKGSF GQVLRCIDYE TGKLVALKII RNKKRFHMQA LVETKILQKI 750
REWDPLDEYC MVQYTDHFYF RDHLCVATEL LGKNLYELIK SNGFKGLPIV 800
VIKSITRQLI QCLTLLNEKH VIHCDLKPEN ILLCHPFKSQ VKVIDFGSSC 850
FEGECVYTYI QSRFYRSPEV ILGMGYGTPI DVWSLGCIIA EMYTGFPLFP 900
GENEQEQLAC IMEIFGPPDH SLIDKCSRKK VFFDSSGKPR PFVSSKGVSR 950
RPFSKSLHQV LQCKDVSFLS FISDCLKWDP DERMTPQQAA QHDFLTGKQD 1000
VRRPNTAPAR QKFARPPNIE TAPIPRPLPN LPMEYNDHTL PSPKEPSNQA 1050
SNLVRSSDKF PNLLTNLDYS IISDNGFLRK PVEKSRP 1087
Length:1,087
Mass (Da):121,146
Last modified:November 1, 1995 - v1
Checksum:i3277E7CA840F8BE2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU329670 Genomic DNA. Translation: CAA90490.1.
PIRiS58147.
RefSeqiNP_592974.1. NM_001018374.2.

Genome annotation databases

EnsemblFungiiSPAC2F7.03c.1; SPAC2F7.03c.1:pep; SPAC2F7.03c.
GeneIDi2541889.
KEGGispo:SPAC2F7.03c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU329670 Genomic DNA. Translation: CAA90490.1 .
PIRi S58147.
RefSeqi NP_592974.1. NM_001018374.2.

3D structure databases

ProteinModelPortali Q09690.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 278379. 193 interactions.
DIPi DIP-59764N.
IntActi Q09690. 3 interactions.
MINTi MINT-4694097.
STRINGi 4896.SPAC2F7.03c-1.

Proteomic databases

MaxQBi Q09690.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii SPAC2F7.03c.1 ; SPAC2F7.03c.1:pep ; SPAC2F7.03c .
GeneIDi 2541889.
KEGGi spo:SPAC2F7.03c.

Organism-specific databases

PomBasei SPAC2F7.03c.

Phylogenomic databases

eggNOGi COG0515.
KOi K08825.
OMAi WIRDISS.
OrthoDBi EOG7WDNBB.
PhylomeDBi Q09690.

Miscellaneous databases

NextBioi 20802976.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "Pom1p, a fission yeast protein kinase that provides positional information for both polarized growth and cytokinesis."
    Baehler J., Pringle J.R.
    Genes Dev. 12:1356-1370(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
    Strain: 972 / ATCC 24843.
  3. "Role of Tea1p, Tea3p and Pom1p in the determination of cell ends in Schizosaccharomyces pombe."
    Niccoli T., Arellano M., Nurse P.
    Yeast 20:1349-1358(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION.
  4. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-513, IDENTIFICATION BY MASS SPECTROMETRY.

Entry informationi

Entry nameiPOM1_SCHPO
AccessioniPrimary (citable) accession number: Q09690
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: July 9, 2014
This is version 118 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi