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Q09652

- GSTK1_CAEEL

UniProt

Q09652 - GSTK1_CAEEL

Protein

Glutathione S-transferase kappa 1

Gene

gstk-1

Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 82 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    RX + glutathione = HX + R-S-glutathione.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei53 – 531GlutathioneBy similarity

    GO - Molecular functioni

    1. glutathione transferase activity Source: UniProtKB-EC
    2. protein disulfide oxidoreductase activity Source: InterPro

    GO - Biological processi

    1. innate immune response Source: WormBase

    Keywords - Molecular functioni

    Transferase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutathione S-transferase kappa 1 (EC:2.5.1.18)
    Alternative name(s):
    GST class-kappa
    Gene namesi
    Name:gstk-1
    ORF Names:ZK1320.1
    OrganismiCaenorhabditis elegans
    Taxonomic identifieri6239 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000001940: Chromosome II

    Organism-specific databases

    WormBaseiZK1320.1; CE01698; WBGene00014251; gstk-1.

    Subcellular locationi

    GO - Cellular componenti

    1. peroxisome Source: WormBase

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 226226Glutathione S-transferase kappa 1PRO_0000185895Add
    BLAST

    Proteomic databases

    PaxDbiQ09652.
    PRIDEiQ09652.

    Interactioni

    Protein-protein interaction databases

    IntActiQ09652. 1 interaction.
    STRINGi6239.ZK1320.1.

    Structurei

    3D structure databases

    ProteinModelPortaliQ09652.
    SMRiQ09652. Positions 4-216.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni15 – 173Glutathione bindingBy similarity
    Regioni199 – 2002Glutathione bindingBy similarity

    Sequence similaritiesi

    Belongs to the GST superfamily. Kappa family.Curated

    Phylogenomic databases

    eggNOGiCOG3917.
    GeneTreeiENSGT00440000033697.
    HOGENOMiHOG000019211.
    InParanoidiQ09652.
    KOiK13299.
    OMAiGRESMKE.
    OrthoDBiEOG793B9B.
    PhylomeDBiQ09652.

    Family and domain databases

    Gene3Di3.40.30.10. 1 hit.
    InterProiIPR001853. DSBA-like_thioredoxin_dom.
    IPR014440. HCCAis_GSTk.
    IPR012336. Thioredoxin-like_fold.
    [Graphical view]
    PfamiPF01323. DSBA. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006386. HCCAis_GSTk. 1 hit.
    SUPFAMiSSF52833. SSF52833. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q09652-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPKLPRIDFY FDVISPYSYI AFEVFQKLET QWKGVTIRYI PFFLGAVMKE    50
    SGNRPPAMLP ARSIMMMTDL KRTAKFWDIP LTPPPLFMEW IKKYRTTGAM 100
    KVLLVLQEQD KELMLRAARE MWVRLWSRSE KIFEDQDFVE VLKAVGVKNP 150
    EQIVEKSKDE KYIKILMENT NKGVDLMAYG APWINVHTED GSEHSFFGSD 200
    RFHLIADLLQ QPQPLPDRLF GQKSKL 226
    Length:226
    Mass (Da):26,482
    Last modified:November 1, 1996 - v1
    Checksum:iDBA39A5994300164
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z46934 Genomic DNA. Translation: CAA87039.1.
    PIRiT27747.
    RefSeqiNP_496082.1. NM_063681.1.
    UniGeneiCel.35643.

    Genome annotation databases

    EnsemblMetazoaiZK1320.1; ZK1320.1; WBGene00014251.
    GeneIDi191563.
    KEGGicel:CELE_ZK1320.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z46934 Genomic DNA. Translation: CAA87039.1 .
    PIRi T27747.
    RefSeqi NP_496082.1. NM_063681.1.
    UniGenei Cel.35643.

    3D structure databases

    ProteinModelPortali Q09652.
    SMRi Q09652. Positions 4-216.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q09652. 1 interaction.
    STRINGi 6239.ZK1320.1.

    Proteomic databases

    PaxDbi Q09652.
    PRIDEi Q09652.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai ZK1320.1 ; ZK1320.1 ; WBGene00014251 .
    GeneIDi 191563.
    KEGGi cel:CELE_ZK1320.1.

    Organism-specific databases

    CTDi 191563.
    WormBasei ZK1320.1 ; CE01698 ; WBGene00014251 ; gstk-1.

    Phylogenomic databases

    eggNOGi COG3917.
    GeneTreei ENSGT00440000033697.
    HOGENOMi HOG000019211.
    InParanoidi Q09652.
    KOi K13299.
    OMAi GRESMKE.
    OrthoDBi EOG793B9B.
    PhylomeDBi Q09652.

    Miscellaneous databases

    NextBioi 949596.
    PROi Q09652.

    Family and domain databases

    Gene3Di 3.40.30.10. 1 hit.
    InterProi IPR001853. DSBA-like_thioredoxin_dom.
    IPR014440. HCCAis_GSTk.
    IPR012336. Thioredoxin-like_fold.
    [Graphical view ]
    Pfami PF01323. DSBA. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006386. HCCAis_GSTk. 1 hit.
    SUPFAMi SSF52833. SSF52833. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      The C. elegans sequencing consortium
      Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2.

    Entry informationi

    Entry nameiGSTK1_CAEEL
    AccessioniPrimary (citable) accession number: Q09652
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 15, 1998
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 82 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programCaenorhabditis annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Caenorhabditis elegans
      Caenorhabditis elegans: entries, gene names and cross-references to WormBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3