Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q09652 (GSTK1_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutathione S-transferase kappa 1

EC=2.5.1.18
Alternative name(s):
GST class-kappa
Gene names
Name:gstk-1
ORF Names:ZK1320.1
OrganismCaenorhabditis elegans [Reference proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length226 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

RX + glutathione = HX + R-S-glutathione.

Sequence similarities

Belongs to the GST superfamily. Kappa family.

Ontologies

Keywords
   Molecular functionTransferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentperoxisome

Inferred from direct assay PubMed 19663909. Source: WormBase

   Molecular_functionglutathione transferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

protein disulfide oxidoreductase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 226226Glutathione S-transferase kappa 1
PRO_0000185895

Regions

Region15 – 173Glutathione binding By similarity
Region199 – 2002Glutathione binding By similarity

Sites

Binding site531Glutathione By similarity

Sequences

Sequence LengthMass (Da)Tools
Q09652 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: DBA39A5994300164

FASTA22626,482
        10         20         30         40         50         60 
MPKLPRIDFY FDVISPYSYI AFEVFQKLET QWKGVTIRYI PFFLGAVMKE SGNRPPAMLP 

        70         80         90        100        110        120 
ARSIMMMTDL KRTAKFWDIP LTPPPLFMEW IKKYRTTGAM KVLLVLQEQD KELMLRAARE 

       130        140        150        160        170        180 
MWVRLWSRSE KIFEDQDFVE VLKAVGVKNP EQIVEKSKDE KYIKILMENT NKGVDLMAYG 

       190        200        210        220 
APWINVHTED GSEHSFFGSD RFHLIADLLQ QPQPLPDRLF GQKSKL 

« Hide

References

[1]"Genome sequence of the nematode C. elegans: a platform for investigating biology."
The C. elegans sequencing consortium
Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Bristol N2.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z46934 Genomic DNA. Translation: CAA87039.1.
PIRT27747.
RefSeqNP_496082.1. NM_063681.1.
UniGeneCel.35643.

3D structure databases

ProteinModelPortalQ09652.
SMRQ09652. Positions 4-216.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ09652. 1 interaction.
STRING6239.ZK1320.1.

Proteomic databases

PaxDbQ09652.
PRIDEQ09652.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaZK1320.1; ZK1320.1; WBGene00014251.
GeneID191563.
KEGGcel:CELE_ZK1320.1.

Organism-specific databases

CTD191563.
WormBaseZK1320.1; CE01698; WBGene00014251; gstk-1.

Phylogenomic databases

eggNOGCOG3917.
GeneTreeENSGT00440000033697.
HOGENOMHOG000019211.
InParanoidQ09652.
KOK13299.
OMAGRESMKE.
OrthoDBEOG793B9B.
PhylomeDBQ09652.

Family and domain databases

Gene3D3.40.30.10. 1 hit.
InterProIPR001853. DSBA-like_thioredoxin_dom.
IPR014440. HCCAis_GSTk.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamPF01323. DSBA. 1 hit.
[Graphical view]
PIRSFPIRSF006386. HCCAis_GSTk. 1 hit.
SUPFAMSSF52833. SSF52833. 1 hit.
ProtoNetSearch...

Other

NextBio949596.
PROQ09652.

Entry information

Entry nameGSTK1_CAEEL
AccessionPrimary (citable) accession number: Q09652
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: June 11, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormBase