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Q09607

- GST36_CAEEL

UniProt

Q09607 - GST36_CAEEL

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Protein

Probable glutathione S-transferase gst-36

Gene
gst-36, R07B1.4
Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles By similarity.

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei8 – 81Glutathione By similarity
Binding sitei39 – 391Glutathione By similarity
Binding sitei43 – 431Glutathione By similarity

GO - Molecular functioni

  1. glutathione transferase activity Source: UniProtKB

GO - Biological processi

  1. metabolic process Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glutathione S-transferase gst-36 (EC:2.5.1.18)
Alternative name(s):
GST class-sigma
Gene namesi
Name:gst-36
ORF Names:R07B1.4
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome X

Organism-specific databases

WormBaseiR07B1.4; CE30562; WBGene00001784; gst-36.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 210210Probable glutathione S-transferase gst-36PRO_0000185933Add
BLAST

Proteomic databases

PaxDbiQ09607.
PRIDEiQ09607.

Interactioni

Protein-protein interaction databases

BioGridi52332. 2 interactions.
IntActiQ09607. 1 interaction.
MINTiMINT-1068164.
STRINGi6239.R07B1.4.

Structurei

3D structure databases

ProteinModelPortaliQ09607.
SMRiQ09607. Positions 1-208.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 7978GST N-terminalAdd
BLAST
Domaini81 – 210130GST C-terminalAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni50 – 512Glutathione binding By similarity
Regioni63 – 642Glutathione binding By similarity

Sequence similaritiesi

Belongs to the GST superfamily. Sigma family.

Phylogenomic databases

eggNOGiNOG293691.
GeneTreeiENSGT00670000097856.
HOGENOMiHOG000115733.
InParanoidiQ09607.
KOiK00799.
OMAiDCARLDM.
OrthoDBiEOG7MH138.
PhylomeDBiQ09607.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q09607-1 [UniParc]FASTAAdd to Basket

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MPHFKFYYFD VRGRGEAIRL LFHLADEKFD DERFGMEQWG VLKSEMPLGQ    50
VPVLEIDGVK ISQTTAIARY LGHQFHRAGT NAVDCARLDM IAEVIQEFMS 100
SSGMGKFSRV LLGMIQANKE QFFKENVLPD VEKYAPIVEK FLLENGNNGL 150
LLGDRETWVD VFAAESFSKL IDYGSPDALD AYPHILALIN RVFNHPNIKK 200
YVSQRKATPA 210
Length:210
Mass (Da):23,876
Last modified:June 20, 2002 - v2
Checksum:i0E6010336B385D9B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z48621 Genomic DNA. Translation: CAA88541.2.
PIRiT23994.
RefSeqiNP_509652.2. NM_077251.4.
UniGeneiCel.19822.

Genome annotation databases

EnsemblMetazoaiR07B1.4; R07B1.4; WBGene00001784.
GeneIDi187645.
KEGGicel:CELE_R07B1.4.
UCSCiR07B1.4. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z48621 Genomic DNA. Translation: CAA88541.2 .
PIRi T23994.
RefSeqi NP_509652.2. NM_077251.4.
UniGenei Cel.19822.

3D structure databases

ProteinModelPortali Q09607.
SMRi Q09607. Positions 1-208.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 52332. 2 interactions.
IntActi Q09607. 1 interaction.
MINTi MINT-1068164.
STRINGi 6239.R07B1.4.

Proteomic databases

PaxDbi Q09607.
PRIDEi Q09607.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai R07B1.4 ; R07B1.4 ; WBGene00001784 .
GeneIDi 187645.
KEGGi cel:CELE_R07B1.4.
UCSCi R07B1.4. c. elegans.

Organism-specific databases

CTDi 187645.
WormBasei R07B1.4 ; CE30562 ; WBGene00001784 ; gst-36.

Phylogenomic databases

eggNOGi NOG293691.
GeneTreei ENSGT00670000097856.
HOGENOMi HOG000115733.
InParanoidi Q09607.
KOi K00799.
OMAi DCARLDM.
OrthoDBi EOG7MH138.
PhylomeDBi Q09607.

Miscellaneous databases

NextBioi 935986.

Family and domain databases

Gene3Di 1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProi IPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view ]
Pfami PF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view ]
SUPFAMi SSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEi PS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiGST36_CAEEL
AccessioniPrimary (citable) accession number: Q09607
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: June 20, 2002
Last modified: June 11, 2014
This is version 96 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi