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Q09607 (GST36_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 96. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable glutathione S-transferase gst-36

EC=2.5.1.18
Alternative name(s):
GST class-sigma
Gene names
Name:gst-36
ORF Names:R07B1.4
OrganismCaenorhabditis elegans [Reference proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length210 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles By similarity.

Catalytic activity

RX + glutathione = HX + R-S-glutathione.

Sequence similarities

Belongs to the GST superfamily. Sigma family.

Contains 1 GST C-terminal domain.

Contains 1 GST N-terminal domain.

Ontologies

Keywords
   Molecular functionTransferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processmetabolic process

Inferred by curator PubMed 8183318. Source: UniProtKB

   Molecular_functionglutathione transferase activity

Non-traceable author statement PubMed 8183318. Source: UniProtKB

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 210210Probable glutathione S-transferase gst-36
PRO_0000185933

Regions

Domain2 – 7978GST N-terminal
Domain81 – 210130GST C-terminal
Region50 – 512Glutathione binding By similarity
Region63 – 642Glutathione binding By similarity

Sites

Binding site81Glutathione By similarity
Binding site391Glutathione By similarity
Binding site431Glutathione By similarity

Sequences

Sequence LengthMass (Da)Tools
Q09607 [UniParc].

Last modified June 20, 2002. Version 2.
Checksum: 0E6010336B385D9B

FASTA21023,876
        10         20         30         40         50         60 
MPHFKFYYFD VRGRGEAIRL LFHLADEKFD DERFGMEQWG VLKSEMPLGQ VPVLEIDGVK 

        70         80         90        100        110        120 
ISQTTAIARY LGHQFHRAGT NAVDCARLDM IAEVIQEFMS SSGMGKFSRV LLGMIQANKE 

       130        140        150        160        170        180 
QFFKENVLPD VEKYAPIVEK FLLENGNNGL LLGDRETWVD VFAAESFSKL IDYGSPDALD 

       190        200        210 
AYPHILALIN RVFNHPNIKK YVSQRKATPA 

« Hide

References

[1]"Genome sequence of the nematode C. elegans: a platform for investigating biology."
The C. elegans sequencing consortium
Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Bristol N2.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z48621 Genomic DNA. Translation: CAA88541.2.
PIRT23994.
RefSeqNP_509652.2. NM_077251.4.
UniGeneCel.19822.

3D structure databases

ProteinModelPortalQ09607.
SMRQ09607. Positions 1-208.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid52332. 2 interactions.
IntActQ09607. 1 interaction.
MINTMINT-1068164.
STRING6239.R07B1.4.

Proteomic databases

PaxDbQ09607.
PRIDEQ09607.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaR07B1.4; R07B1.4; WBGene00001784.
GeneID187645.
KEGGcel:CELE_R07B1.4.
UCSCR07B1.4. c. elegans.

Organism-specific databases

CTD187645.
WormBaseR07B1.4; CE30562; WBGene00001784; gst-36.

Phylogenomic databases

eggNOGNOG293691.
GeneTreeENSGT00670000097856.
HOGENOMHOG000115733.
InParanoidQ09607.
KOK00799.
OMADCARLDM.
OrthoDBEOG7MH138.
PhylomeDBQ09607.

Family and domain databases

Gene3D1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio935986.

Entry information

Entry nameGST36_CAEEL
AccessionPrimary (citable) accession number: Q09607
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: June 20, 2002
Last modified: June 11, 2014
This is version 96 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormBase