ID   PPAX_CAEEL              Reviewed;         435 AA.
AC   Q09549; Q17843;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   20-JAN-2009, sequence version 5.
DT   27-MAR-2024, entry version 120.
DE   RecName: Full=Putative acid phosphatase F26C11.1;
DE            EC=3.1.3.2;
GN   ORFNames=F26C11.1;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a phosphate monoester + H2O = an alcohol + phosphate;
CC         Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2;
CC   -!- SIMILARITY: Belongs to the histidine acid phosphatase family.
CC       {ECO:0000305}.
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DR   EMBL; Z47072; CAA87370.2; -; Genomic_DNA.
DR   PIR; T19118; T19118.
DR   RefSeq; NP_496137.2; NM_063736.2.
DR   AlphaFoldDB; Q09549; -.
DR   SMR; Q09549; -.
DR   STRING; 6239.F26C11.1.1; -.
DR   PaxDb; 6239-F26C11-1; -.
DR   EnsemblMetazoa; F26C11.1.1; F26C11.1.1; WBGene00009146.
DR   EnsemblMetazoa; F26C11.1.2; F26C11.1.2; WBGene00009146.
DR   GeneID; 184959; -.
DR   KEGG; cel:CELE_F26C11.1; -.
DR   UCSC; F26C11.1; c. elegans.
DR   AGR; WB:WBGene00009146; -.
DR   WormBase; F26C11.1; CE01559; WBGene00009146; -.
DR   eggNOG; KOG3720; Eukaryota.
DR   GeneTree; ENSGT00940000168803; -.
DR   HOGENOM; CLU_030431_2_0_1; -.
DR   InParanoid; Q09549; -.
DR   OMA; KLEFVQT; -.
DR   OrthoDB; 5477542at2759; -.
DR   PhylomeDB; Q09549; -.
DR   PRO; PR:Q09549; -.
DR   Proteomes; UP000001940; Chromosome II.
DR   Bgee; WBGene00009146; Expressed in adult organism and 1 other cell type or tissue.
DR   GO; GO:0003993; F:acid phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016791; F:phosphatase activity; IBA:GO_Central.
DR   GO; GO:0016311; P:dephosphorylation; IBA:GO_Central.
DR   CDD; cd07061; HP_HAP_like; 1.
DR   Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR   InterPro; IPR033379; Acid_Pase_AS.
DR   InterPro; IPR000560; His_Pase_clade-2.
DR   InterPro; IPR029033; His_PPase_superfam.
DR   PANTHER; PTHR11567; ACID PHOSPHATASE-RELATED; 1.
DR   PANTHER; PTHR11567:SF25; PROTEIN FRA10AC1; 1.
DR   Pfam; PF00328; His_Phos_2; 1.
DR   SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
DR   PROSITE; PS00616; HIS_ACID_PHOSPHAT_1; 1.
DR   PROSITE; PS00778; HIS_ACID_PHOSPHAT_2; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Hydrolase; Reference proteome.
FT   CHAIN           1..435
FT                   /note="Putative acid phosphatase F26C11.1"
FT                   /id="PRO_0000114470"
FT   ACT_SITE        38
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        317
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000250"
FT   DISULFID        382..388
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   435 AA;  50091 MW;  504CE11408536E0E CRC64;
     MNKLLIFIML VTFLAIEKSF MSEVDNMKLE FVQTIWRHGD RSALEGLFPI SEKNWTFGGG
     GLGELTPMGM SEMNNLGTIF RRRYVEDQQF LSHRYAAKEI YIRSTNLNRT IISAMSLLYG
     MFPPGAWNIQ GVDYPNDVDW QQGFTFIPVH VDGIDQCAVA QLCNCRRFQE LQEKWAELDE
     VKNATVAMIA LNRRVAAFYN VTDQPEKFNR YTDAWKCQRN WFNDTMYQQL PWYNEDLYNE
     AQRTYAPFKR FTEGNFAKPS IVDGIDIPQE VSTLQGGPLL NEIFERGREK IRCVADAENC
     SIDYLKPLKF YAYSSHDQLV YALLVTLGIT DVVKTVDGWP DTSSSLTIEY YSNPGNQSSV
     KFLYRDNSND NFSDVTSQIP VCNGAQYCAM SDFQNIAYQF KPLPDYMTLC ETSLSSISSV
     LNNKIWVFVI IYFLI
//