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Q09549

- PPAX_CAEEL

UniProt

Q09549 - PPAX_CAEEL

Protein

Putative acid phosphatase F26C11.1

Gene

F26C11.1

Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 5 (20 Jan 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    A phosphate monoester + H2O = an alcohol + phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei38 – 381NucleophileBy similarity
    Active sitei317 – 3171Proton donorBy similarity

    GO - Molecular functioni

    1. acid phosphatase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Hydrolase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative acid phosphatase F26C11.1 (EC:3.1.3.2)
    Gene namesi
    ORF Names:F26C11.1
    OrganismiCaenorhabditis elegans
    Taxonomic identifieri6239 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

    Organism-specific databases

    WormBaseiF26C11.1; CE01559; WBGene00009146.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 435435Putative acid phosphatase F26C11.1PRO_0000114470Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi382 ↔ 388By similarity

    Keywords - PTMi

    Disulfide bond

    Interactioni

    Protein-protein interaction databases

    STRINGi6239.F26C11.1.

    Structurei

    3D structure databases

    ProteinModelPortaliQ09549.
    SMRiQ09549. Positions 28-412.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the histidine acid phosphatase family.Curated

    Phylogenomic databases

    eggNOGiNOG286121.
    GeneTreeiENSGT00530000062956.
    HOGENOMiHOG000016204.
    InParanoidiQ09549.
    KOiK01078.
    OMAiKLEFVQT.
    OrthoDBiEOG7GXPBJ.
    PhylomeDBiQ09549.

    Family and domain databases

    Gene3Di3.40.50.1240. 1 hit.
    InterProiIPR000560. His_Pase_superF_clade-2.
    IPR029033. His_PPase_superfam.
    [Graphical view]
    PfamiPF00328. His_Phos_2. 1 hit.
    [Graphical view]
    SUPFAMiSSF53254. SSF53254. 1 hit.
    PROSITEiPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
    PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
    [Graphical view]
    ProtoNetiSearch...

    Sequencei

    Sequence statusi: Complete.

    Q09549-1 [UniParc]FASTAAdd to Basket

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    MNKLLIFIML VTFLAIEKSF MSEVDNMKLE FVQTIWRHGD RSALEGLFPI    50
    SEKNWTFGGG GLGELTPMGM SEMNNLGTIF RRRYVEDQQF LSHRYAAKEI 100
    YIRSTNLNRT IISAMSLLYG MFPPGAWNIQ GVDYPNDVDW QQGFTFIPVH 150
    VDGIDQCAVA QLCNCRRFQE LQEKWAELDE VKNATVAMIA LNRRVAAFYN 200
    VTDQPEKFNR YTDAWKCQRN WFNDTMYQQL PWYNEDLYNE AQRTYAPFKR 250
    FTEGNFAKPS IVDGIDIPQE VSTLQGGPLL NEIFERGREK IRCVADAENC 300
    SIDYLKPLKF YAYSSHDQLV YALLVTLGIT DVVKTVDGWP DTSSSLTIEY 350
    YSNPGNQSSV KFLYRDNSND NFSDVTSQIP VCNGAQYCAM SDFQNIAYQF 400
    KPLPDYMTLC ETSLSSISSV LNNKIWVFVI IYFLI 435
    Length:435
    Mass (Da):50,091
    Last modified:January 20, 2009 - v5
    Checksum:i504CE11408536E0E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z47072 Genomic DNA. Translation: CAA87370.2.
    PIRiT19118.
    RefSeqiNP_496137.2. NM_063736.2.
    UniGeneiCel.26587.

    Genome annotation databases

    EnsemblMetazoaiF26C11.1; F26C11.1; WBGene00009146.
    GeneIDi184959.
    KEGGicel:CELE_F26C11.1.
    UCSCiF26C11.1. c. elegans.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z47072 Genomic DNA. Translation: CAA87370.2 .
    PIRi T19118.
    RefSeqi NP_496137.2. NM_063736.2.
    UniGenei Cel.26587.

    3D structure databases

    ProteinModelPortali Q09549.
    SMRi Q09549. Positions 28-412.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 6239.F26C11.1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai F26C11.1 ; F26C11.1 ; WBGene00009146 .
    GeneIDi 184959.
    KEGGi cel:CELE_F26C11.1.
    UCSCi F26C11.1. c. elegans.

    Organism-specific databases

    CTDi 184959.
    WormBasei F26C11.1 ; CE01559 ; WBGene00009146 .

    Phylogenomic databases

    eggNOGi NOG286121.
    GeneTreei ENSGT00530000062956.
    HOGENOMi HOG000016204.
    InParanoidi Q09549.
    KOi K01078.
    OMAi KLEFVQT.
    OrthoDBi EOG7GXPBJ.
    PhylomeDBi Q09549.

    Miscellaneous databases

    NextBioi 926558.

    Family and domain databases

    Gene3Di 3.40.50.1240. 1 hit.
    InterProi IPR000560. His_Pase_superF_clade-2.
    IPR029033. His_PPase_superfam.
    [Graphical view ]
    Pfami PF00328. His_Phos_2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53254. SSF53254. 1 hit.
    PROSITEi PS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
    PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      The C. elegans sequencing consortium
      Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2.

    Entry informationi

    Entry nameiPPAX_CAEEL
    AccessioniPrimary (citable) accession number: Q09549
    Secondary accession number(s): Q17843
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: January 20, 2009
    Last modified: October 1, 2014
    This is version 86 of the entry and version 5 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programCaenorhabditis annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Caenorhabditis elegans
      Caenorhabditis elegans: entries, gene names and cross-references to WormBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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