Q09549 (PPAX_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative acid phosphatase F26C11.1
EC=3.1.3.2

Gene names

ORF Names:

F26C11.1

Organism

Caenorhabditis elegans [Reference proteome]

Taxonomic identifier

6239 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	435 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	A phosphate monoester + H2O = an alcohol + phosphate.
Sequence similarities	Belongs to the histidine acid phosphatase family.

Ontologies

Keywords
Molecular function	Hydrolase
PTM	Disulfide bond
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	acid phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 435	435	Putative acid phosphatase F26C11.1		PRO_0000114470
Sites
	Active site	38	1	Nucleophile By similarity
	Active site	317	1	Proton donor By similarity
Amino acid modifications
	Disulfide bond	382 ↔ 388		By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q09549 [UniParc]. Last modified January 20, 2009. Version 5. Checksum: 504CE11408536E0E	FASTA	435	50,091
	10 20 30 40 50 60 MNKLLIFIML VTFLAIEKSF MSEVDNMKLE FVQTIWRHGD RSALEGLFPI SEKNWTFGGG 70 80 90 100 110 120 GLGELTPMGM SEMNNLGTIF RRRYVEDQQF LSHRYAAKEI YIRSTNLNRT IISAMSLLYG 130 140 150 160 170 180 MFPPGAWNIQ GVDYPNDVDW QQGFTFIPVH VDGIDQCAVA QLCNCRRFQE LQEKWAELDE 190 200 210 220 230 240 VKNATVAMIA LNRRVAAFYN VTDQPEKFNR YTDAWKCQRN WFNDTMYQQL PWYNEDLYNE 250 260 270 280 290 300 AQRTYAPFKR FTEGNFAKPS IVDGIDIPQE VSTLQGGPLL NEIFERGREK IRCVADAENC 310 320 330 340 350 360 SIDYLKPLKF YAYSSHDQLV YALLVTLGIT DVVKTVDGWP DTSSSLTIEY YSNPGNQSSV 370 380 390 400 410 420 KFLYRDNSND NFSDVTSQIP VCNGAQYCAM SDFQNIAYQF KPLPDYMTLC ETSLSSISSV 430 LNNKIWVFVI IYFLI

References

[1]	"Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z47072 Genomic DNA. Translation: CAA87370.2.
PIR	T19118.
RefSeq	NP_496137.2. NM_063736.2.
UniGene	Cel.26587.
3D structure databases
ProteinModelPortal	Q09549.
SMR	Q09549. Positions 28-412.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	F26C11.1; F26C11.1; F26C11.1.
GeneID	184959.
KEGG	cel:CELE_F26C11.1.
UCSC	F26C11.1. c. elegans.
Organism-specific databases
CTD	184959.
WormBase	F26C11.1; CE01559; WBGene00009146.
Phylogenomic databases
eggNOG	NOG286121.
GeneTree	ENSGT00530000062956.
HOGENOM	HOG000016204.
InParanoid	Q09549.
KO	K01078.
OMA	KLEFVQT.
Family and domain databases
InterPro	IPR000560. His_Pase_superF_clade-2. [Graphical view]
Pfam	PF00328. His_Phos_2. 1 hit. [Graphical view]
PROSITE	PS00616. HIS_ACID_PHOSPHAT_1. 1 hit. PS00778. HIS_ACID_PHOSPHAT_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	926558.

Entry information

Entry name

PPAX_CAEEL

Accession

Primary (citable) accession number: Q09549
Secondary accession number(s): Q17843

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	January 20, 2009
Last modified:	May 1, 2013
This is version 79 of the entry and version 5 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Caenorhabditis annotation project