Reviewed, UniProtKB/Swiss-Prot Q09527 (KAD6_CAEEL)

Names and origin

Protein names

Recommended name:
    Probable adenylate kinase isoenzyme 6
    EC=2.7.4.3
Alternative name(s):
    ATP-AMP transphosphorylase 6

Gene names

ORF Names:

E02H1.6

Organism

Caenorhabditis elegans [Complete proteome]

Taxonomic identifier

6239 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	182 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	ATP + AMP = 2 ADP.
Subcellular location	Nucleus By similarity.
Sequence similarities	Belongs to the adenylate kinase family. AK6 subfamily.

Ontologies

Keywords
Cellular component	Nucleus
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	growth Inferred from mutant phenotype. Source: WormBase nematode larval development Inferred from mutant phenotype. Source: WormBase positive regulation of growth rate Inferred from mutant phenotype. Source: WormBase
Cellular component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW adenylate kinase activity Inferred from electronic annotation. Source: EC shikimate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 182	182	Probable adenylate kinase isoenzyme 6		PRO_0000153900
Regions
	Nucleotide binding	16 – 23	8	ATP Potential
	Compositional bias	121 – 177	57	Glu-rich

Sequences

	Sequence		Length	Mass (Da)
	Q09527-1 [UniParc]. Last modified June 6, 2002. Version 2. Checksum: 49FCC86D29462765	FASTA	182	21,024
	10 20 30 40 50 60 MATPETRRRP NILVTGSPGT GKSTLGQQVA EKLGFVFIEV SKEVRENNLQ GDFDEQYNCH 70 80 90 100 110 120 VLDEDKLLDH ISDRLDSDEG GIVVDYHGCD LFPERWFDVV VVLRCPTEKL YDRLQSRGYS 130 140 150 160 170 180 EFKIKENVEC EIFGTLLEEA RESYSEDIVH ELQSETTEQM EENLERICEL AGEFKNEHTM EQ

References

[1]	"Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed: 9851916] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	Z47075 Genomic DNA. Translation: CAA87383.2.
PIR	T20418.
RefSeq	NP_496065.1.
UniGene	Cel.15560
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	E02H1.6. Caenorhabditis elegans. [Contig view]
GeneID	174511.
KEGG	cel:E02H1.6.
NMPDR	fig|6239.3.peg.6968.
Organism-specific databases
WormBase	WBGene00008458. E02H1.6.
WormPep	E02H1.6. CE28286. [WorfDB]
Phylogenomic databases
OMA	Q09527. LFPERWF.
Enzyme and pathway databases
BRENDA	2.7.4.3. 672.
Gene expression databases
ArrayExpress	Q09527.
Family and domain databases
InterPro	IPR003959. ATPase_AAA_core. IPR000623. Shik_kinase. [Graphical view]
Pfam	PF00004. AAA. 1 hit. [Graphical view]
PRINTS	PR01100. SHIKIMTKNASE.
ProtoNet	Search...
Other Resources
NextBio	884340.

Entry information

Entry name

KAD6_CAEEL

Accession

Primary (citable) accession number: Q09527

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	June 6, 2002
Last modified:	June 16, 2009
This is version 59 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Caenorhabditis annotation project