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Q09496 (PPH6_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 107. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative serine/threonine-protein phosphatase pph-6

EC=3.1.3.16
Gene names
Name:pph-6
ORF Names:C34C12.3
OrganismCaenorhabditis elegans [Reference proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length331 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 1 iron ion per subunit By similarity.

Binds 1 manganese ion per subunit By similarity.

Sequence similarities

Belongs to the PPP phosphatase family. PP-X subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 331331Putative serine/threonine-protein phosphatase pph-6
PRO_0000058917

Sites

Active site1401Proton donor By similarity
Metal binding791Iron By similarity
Metal binding811Iron By similarity
Metal binding1071Iron By similarity
Metal binding1071Manganese By similarity
Metal binding1391Manganese By similarity
Metal binding1891Manganese By similarity
Metal binding2641Manganese By similarity

Sequences

Sequence LengthMass (Da)Tools
Q09496 [UniParc].

Last modified January 17, 2003. Version 2.
Checksum: ACE68C04772E9262

FASTA33137,388
        10         20         30         40         50         60 
MIDTNLLRVT VCDEGELEKS TTHFIGSRKI EPEQWITWAS ECKYLPESDA VALCATLIDR 

        70         80         90        100        110        120 
LSLEANVVPV SSPVTICGDI HGQFYDLLEL FKTGGTVPNT KYVFMGDYVD RGHYSLETVT 

       130        140        150        160        170        180 
LLFCLLLKYP NQITLLRGNH ESRRISNVYG FYDECQNKYG HGNVHKWFCK VFDVLPIGAL 

       190        200        210        220        230        240 
IDESVLCVHG GLSPDIRTID SLMLLDRAQE VPNKGPLCDI MWSDPDDDVE DWVISQRGAG 

       250        260        270        280        290        300 
FVFGAKVTEE FLMNNDLSLL CRSHQLVDEG FKYMFNEKLA TVWSAPNYCY RCGNAAAVFE 

       310        320        330 
IDGNNRSTKY FNAVPDGSRE KPDRVVAPYF L 

« Hide

References

[1]"Genome sequence of the nematode C. elegans: a platform for investigating biology."
The C. elegans sequencing consortium
Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Bristol N2.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z46996 Genomic DNA. Translation: CAA87100.2.
PIRT19701.
RefSeqNP_497714.2. NM_065313.5.
UniGeneCel.19977.

3D structure databases

ProteinModelPortalQ09496.
SMRQ09496. Positions 31-331.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid48030. 4 interactions.
IntActQ09496. 1 interaction.
STRING6239.C34C12.3.

Proteomic databases

PaxDbQ09496.
PRIDEQ09496.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaC34C12.3; C34C12.3; C34C12.3.
GeneID183199.
KEGGcel:CELE_C34C12.3.
UCSCC34C12.3. c. elegans.

Organism-specific databases

CTD183199.
WormBaseC34C12.3; CE31433; WBGene00007922; pph-6.

Phylogenomic databases

eggNOGCOG0639.
HOGENOMHOG000172696.
InParanoidQ09496.
KOK15498.
OMAWITWASE.
OrthoDBEOG7B8S44.
PhylomeDBQ09496.

Family and domain databases

InterProIPR004843. Calcineurin-like_PHP_apaH.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSPR00114. STPHPHTASE.
SMARTSM00156. PP2Ac. 1 hit.
[Graphical view]
PROSITEPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio920272.
PROQ09496.

Entry information

Entry namePPH6_CAEEL
AccessionPrimary (citable) accession number: Q09496
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: January 17, 2003
Last modified: April 16, 2014
This is version 107 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormBase