Reviewed, UniProtKB/Swiss-Prot Q09451 (PPAW_CAEEL)

Names and origin

Protein names

Recommended name:
    Putative acid phosphatase C05C10.4
    EC=3.1.3.2

Gene names

ORF Names:

C05C10.4

Organism

Caenorhabditis elegans [Complete proteome]

Taxonomic identifier

6239 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	413 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	A phosphate monoester + H2O = an alcohol + phosphate.
Sequence similarities	Belongs to the histidine acid phosphatase family.

Ontologies

Keywords
Molecular function	Hydrolase
PTM	Disulfide bond
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	acid phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 413	413	Putative acid phosphatase C05C10.4		PRO_0000114469
Regions
	Compositional bias	55 – 60	6	Poly-Gly
Sites
	Active site	35	1	Nucleophile By similarity
	Active site	315	1	Proton donor By similarity
Amino acid modifications
	Disulfide bond	381 ↔ 387		By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q09451-1 [UniParc]. Last modified December 15, 1998. Version 2. Checksum: BFFC70995EA903F0	FASTA	413	46,617
	10 20 30 40 50 60 MMISIFSLLA STAILVFANG QSNVKLEFVQ AMWRHGERAS QVDQYPIYEK DWIYGGGGLG 70 80 90 100 110 120 ELTAIGMGEM NELGWLIRKR YVTKLKFLTP KYASREVYFR STNFNRTIIS AQSLLYGLFP 130 140 150 160 170 180 PSLYDVKNVD YPYSPLTWFP GFTFVPVHVD GPDQCAASQN CPCTRYDLLQ GQMLTLPEVL 190 200 210 220 230 240 PKYTQVVLLN RRVGGYYNMT SGLDSFTTYP DTWKCQRAYF NRTMYAKLPW YNEELYYQAQ 250 260 270 280 290 300 VTYAPVKGFL EGNFENPAVT SSGLDVGLEI KKVRSGVIIN EVFNRANEKL NCAELGQNCT 310 320 330 340 350 360 SYLNKLKFYG YSIHDNNVYG VLVALGIPQI ANTLDGWPAY AAGIFMEFHR NTSTNERFFK 370 380 390 400 410 VLYREGDDTP ISDVTSQLPI CNGATLCPLG ALQTLAETLK PLPDITTLCK TPL

References

[1]	"Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed: 9851916] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	Z48178 Genomic DNA. Translation: CAA88205.1.
PIR	T18945.
RefSeq	NP_496143.1.
UniGene	Cel.15981
3D structure databases
HSSP	HSSP built from PDB template 1ND5 based on UniProtKB P15309.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q09451. 1 interaction.
Genome annotation databases
Ensembl	C05C10.4. Caenorhabditis elegans. [Contig view]
GeneID	174547.
KEGG	cel:C05C10.4.
NMPDR	fig|6239.3.peg.7074.
Organism-specific databases
WormBase	WBGene00007331. C05C10.4.
WormPep	C05C10.4. CE17370. [WorfDB]
Phylogenomic databases
OMA	Q09451. HGERASQ.
Enzyme and pathway databases
BRENDA	3.1.3.2. 672.
Gene expression databases
ArrayExpress	Q09451.
Family and domain databases
InterPro	IPR000560. Histidine_acid_Pase. [Graphical view]
Pfam	PF00328. Acid_phosphat_A. 1 hit. [Graphical view]
PROSITE	PS00616. HIS_ACID_PHOSPHAT_1. 1 hit. PS00778. HIS_ACID_PHOSPHAT_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	884502.

Entry information

Entry name

PPAW_CAEEL

Accession

Primary (citable) accession number: Q09451

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	December 15, 1998
Last modified:	June 16, 2009
This is version 57 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Caenorhabditis annotation project