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Protein

Putative acid phosphatase 11

Gene

pho-11

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei35 – 351NucleophileBy similarity
Active sitei315 – 3151Proton donorBy similarity

GO - Molecular functioni

  1. acid phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Putative acid phosphatase 11 (EC:3.1.3.2)
Gene namesi
Name:pho-11
ORF Names:C05C10.4
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiC05C10.4; CE17370; WBGene00007331; pho-11.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 413413Putative acid phosphatase 11PRO_0000114469Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi381 ↔ 387By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ09451.

Interactioni

Protein-protein interaction databases

BioGridi39869. 1 interaction.
IntActiQ09451. 1 interaction.
MINTiMINT-228178.
STRINGi6239.C05C10.4.1.

Structurei

3D structure databases

ProteinModelPortaliQ09451.
SMRiQ09451. Positions 25-411.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi55 – 606Poly-Gly

Sequence similaritiesi

Belongs to the histidine acid phosphatase family.Curated

Phylogenomic databases

eggNOGiNOG284330.
GeneTreeiENSGT00530000062956.
HOGENOMiHOG000016204.
InParanoidiQ09451.
KOiK01078.
OMAiIYEKDWI.
PhylomeDBiQ09451.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
InterProiIPR000560. His_Pase_superF_clade-2.
IPR029033. His_PPase_superfam.
[Graphical view]
PfamiPF00328. His_Phos_2. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
PROSITEiPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q09451-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMISIFSLLA STAILVFANG QSNVKLEFVQ AMWRHGERAS QVDQYPIYEK
60 70 80 90 100
DWIYGGGGLG ELTAIGMGEM NELGWLIRKR YVTKLKFLTP KYASREVYFR
110 120 130 140 150
STNFNRTIIS AQSLLYGLFP PSLYDVKNVD YPYSPLTWFP GFTFVPVHVD
160 170 180 190 200
GPDQCAASQN CPCTRYDLLQ GQMLTLPEVL PKYTQVVLLN RRVGGYYNMT
210 220 230 240 250
SGLDSFTTYP DTWKCQRAYF NRTMYAKLPW YNEELYYQAQ VTYAPVKGFL
260 270 280 290 300
EGNFENPAVT SSGLDVGLEI KKVRSGVIIN EVFNRANEKL NCAELGQNCT
310 320 330 340 350
SYLNKLKFYG YSIHDNNVYG VLVALGIPQI ANTLDGWPAY AAGIFMEFHR
360 370 380 390 400
NTSTNERFFK VLYREGDDTP ISDVTSQLPI CNGATLCPLG ALQTLAETLK
410
PLPDITTLCK TPL
Length:413
Mass (Da):46,617
Last modified:December 15, 1998 - v2
Checksum:iBFFC70995EA903F0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z48178 Genomic DNA. Translation: CAA88205.1.
PIRiT18945.
RefSeqiNP_496143.1. NM_063742.6.
UniGeneiCel.15981.

Genome annotation databases

EnsemblMetazoaiC05C10.4.1; C05C10.4.1; WBGene00007331.
C05C10.4.2; C05C10.4.2; WBGene00007331.
C05C10.4.3; C05C10.4.3; WBGene00007331.
GeneIDi174547.
KEGGicel:CELE_C05C10.4.
UCSCiC05C10.4.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z48178 Genomic DNA. Translation: CAA88205.1.
PIRiT18945.
RefSeqiNP_496143.1. NM_063742.6.
UniGeneiCel.15981.

3D structure databases

ProteinModelPortaliQ09451.
SMRiQ09451. Positions 25-411.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi39869. 1 interaction.
IntActiQ09451. 1 interaction.
MINTiMINT-228178.
STRINGi6239.C05C10.4.1.

Proteomic databases

PaxDbiQ09451.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC05C10.4.1; C05C10.4.1; WBGene00007331.
C05C10.4.2; C05C10.4.2; WBGene00007331.
C05C10.4.3; C05C10.4.3; WBGene00007331.
GeneIDi174547.
KEGGicel:CELE_C05C10.4.
UCSCiC05C10.4.1. c. elegans.

Organism-specific databases

CTDi174547.
WormBaseiC05C10.4; CE17370; WBGene00007331; pho-11.

Phylogenomic databases

eggNOGiNOG284330.
GeneTreeiENSGT00530000062956.
HOGENOMiHOG000016204.
InParanoidiQ09451.
KOiK01078.
OMAiIYEKDWI.
PhylomeDBiQ09451.

Miscellaneous databases

NextBioi884502.
PROiQ09451.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
InterProiIPR000560. His_Pase_superF_clade-2.
IPR029033. His_PPase_superfam.
[Graphical view]
PfamiPF00328. His_Phos_2. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
PROSITEiPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiPHO11_CAEEL
AccessioniPrimary (citable) accession number: Q09451
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: December 15, 1998
Last modified: April 29, 2015
This is version 91 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.