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Protein

Putative acid phosphatase 10

Gene

pho-10

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei33 – 331NucleophileBy similarity
Active sitei313 – 3131Proton donorBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Putative acid phosphatase 10 (EC:3.1.3.2)
Gene namesi
Name:pho-10
ORF Names:C05C10.1
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiC05C10.1; CE42840; WBGene00007328; pho-10.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 411411Putative acid phosphatase 10PRO_0000114468Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi379 ↔ 385By similarity

Keywords - PTMi

Disulfide bond

Interactioni

Protein-protein interaction databases

STRINGi6239.C05C10.1.

Structurei

3D structure databases

ProteinModelPortaliQ09448.
SMRiQ09448. Positions 22-399.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the histidine acid phosphatase family.Curated

Phylogenomic databases

eggNOGiNOG85977.
GeneTreeiENSGT00530000062956.
HOGENOMiHOG000016204.
InParanoidiQ09448.
KOiK01078.
OMAiIPHISAT.
PhylomeDBiQ09448.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
InterProiIPR000560. His_Pase_superF_clade-2.
IPR029033. His_PPase_superfam.
[Graphical view]
PfamiPF00328. His_Phos_2. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
PROSITEiPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q09448-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLSLFCVII VAVGCSSKDG NVKLEFVQAM WRHGERSALA DLYPIYEKDW
60 70 80 90 100
VFGGGGLGEL TGRGMGEMNN LGRLIRERYV RKFNFLEPKY ASKEVYFRST
110 120 130 140 150
NLNRTIISAM SLLYGLFPPS LYDIPNVDYP FTPLKWLPGL AFVPVHVDGS
160 170 180 190 200
DQCAASQNCP CPRYDFLQQQ MLTLPEVQQA FQQVILLNRQ IAPLYNVTTG
210 220 230 240 250
VDTFYVYPDT WKCQRAYFNK TMYDKLPWYN EQLYSKAEIT YAPIKGFLEG
260 270 280 290 300
SFSQPAVTSN GLDVAFEIQQ VRSGVMINEI VSRASEKLNC VERGQNCTSY
310 320 330 340 350
LNKLKFYGYS IHDNNVYAVL VALGIPHISA TEDGWPSYAA AIFFEFYRNS
360 370 380 390 400
QTNKRLFKVL YRQDASSQIT DVTSQVPMCQ GVSMCPLSTF QHLADVLKPI
410
PDINTVCNIT S
Length:411
Mass (Da):46,600
Last modified:January 20, 2009 - v2
Checksum:iA18761D5232B00C3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z48178 Genomic DNA. Translation: CAA88204.2.
PIRiT18944.
RefSeqiNP_496140.2. NM_063739.2.
UniGeneiCel.25704.

Genome annotation databases

EnsemblMetazoaiC05C10.1; C05C10.1; WBGene00007328.
GeneIDi182251.
KEGGicel:CELE_C05C10.1.
UCSCiC05C10.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z48178 Genomic DNA. Translation: CAA88204.2.
PIRiT18944.
RefSeqiNP_496140.2. NM_063739.2.
UniGeneiCel.25704.

3D structure databases

ProteinModelPortaliQ09448.
SMRiQ09448. Positions 22-399.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.C05C10.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC05C10.1; C05C10.1; WBGene00007328.
GeneIDi182251.
KEGGicel:CELE_C05C10.1.
UCSCiC05C10.1. c. elegans.

Organism-specific databases

CTDi182251.
WormBaseiC05C10.1; CE42840; WBGene00007328; pho-10.

Phylogenomic databases

eggNOGiNOG85977.
GeneTreeiENSGT00530000062956.
HOGENOMiHOG000016204.
InParanoidiQ09448.
KOiK01078.
OMAiIPHISAT.
PhylomeDBiQ09448.

Miscellaneous databases

NextBioi916916.
PROiQ09448.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
InterProiIPR000560. His_Pase_superF_clade-2.
IPR029033. His_PPase_superfam.
[Graphical view]
PfamiPF00328. His_Phos_2. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
PROSITEiPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiPHO10_CAEEL
AccessioniPrimary (citable) accession number: Q09448
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: January 20, 2009
Last modified: April 29, 2015
This is version 83 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.