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Q09448

- PHO10_CAEEL

UniProt

Q09448 - PHO10_CAEEL

Protein

Putative acid phosphatase 10

Gene

pho-10

Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 2 (20 Jan 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    A phosphate monoester + H2O = an alcohol + phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei33 – 331NucleophileBy similarity
    Active sitei313 – 3131Proton donorBy similarity

    GO - Molecular functioni

    1. acid phosphatase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Hydrolase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative acid phosphatase 10 (EC:3.1.3.2)
    Gene namesi
    Name:pho-10
    ORF Names:C05C10.1
    OrganismiCaenorhabditis elegans
    Taxonomic identifieri6239 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000001940: Chromosome II

    Organism-specific databases

    WormBaseiC05C10.1; CE42840; WBGene00007328; pho-10.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 411411Putative acid phosphatase 10PRO_0000114468Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi379 ↔ 385By similarity

    Keywords - PTMi

    Disulfide bond

    Interactioni

    Protein-protein interaction databases

    STRINGi6239.C05C10.1.

    Structurei

    3D structure databases

    ProteinModelPortaliQ09448.
    SMRiQ09448. Positions 22-399.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the histidine acid phosphatase family.Curated

    Phylogenomic databases

    eggNOGiNOG85977.
    GeneTreeiENSGT00530000062956.
    HOGENOMiHOG000016204.
    InParanoidiQ09448.
    KOiK01078.
    PhylomeDBiQ09448.

    Family and domain databases

    Gene3Di3.40.50.1240. 1 hit.
    InterProiIPR000560. His_Pase_superF_clade-2.
    IPR029033. His_PPase_superfam.
    [Graphical view]
    PfamiPF00328. His_Phos_2. 1 hit.
    [Graphical view]
    SUPFAMiSSF53254. SSF53254. 1 hit.
    PROSITEiPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
    PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q09448-1 [UniParc]FASTAAdd to Basket

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    MFLSLFCVII VAVGCSSKDG NVKLEFVQAM WRHGERSALA DLYPIYEKDW    50
    VFGGGGLGEL TGRGMGEMNN LGRLIRERYV RKFNFLEPKY ASKEVYFRST 100
    NLNRTIISAM SLLYGLFPPS LYDIPNVDYP FTPLKWLPGL AFVPVHVDGS 150
    DQCAASQNCP CPRYDFLQQQ MLTLPEVQQA FQQVILLNRQ IAPLYNVTTG 200
    VDTFYVYPDT WKCQRAYFNK TMYDKLPWYN EQLYSKAEIT YAPIKGFLEG 250
    SFSQPAVTSN GLDVAFEIQQ VRSGVMINEI VSRASEKLNC VERGQNCTSY 300
    LNKLKFYGYS IHDNNVYAVL VALGIPHISA TEDGWPSYAA AIFFEFYRNS 350
    QTNKRLFKVL YRQDASSQIT DVTSQVPMCQ GVSMCPLSTF QHLADVLKPI 400
    PDINTVCNIT S 411
    Length:411
    Mass (Da):46,600
    Last modified:January 20, 2009 - v2
    Checksum:iA18761D5232B00C3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z48178 Genomic DNA. Translation: CAA88204.2.
    PIRiT18944.
    RefSeqiNP_496140.2. NM_063739.2.
    UniGeneiCel.25704.

    Genome annotation databases

    EnsemblMetazoaiC05C10.1; C05C10.1; WBGene00007328.
    GeneIDi182251.
    KEGGicel:CELE_C05C10.1.
    UCSCiC05C10.1. c. elegans.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z48178 Genomic DNA. Translation: CAA88204.2 .
    PIRi T18944.
    RefSeqi NP_496140.2. NM_063739.2.
    UniGenei Cel.25704.

    3D structure databases

    ProteinModelPortali Q09448.
    SMRi Q09448. Positions 22-399.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 6239.C05C10.1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai C05C10.1 ; C05C10.1 ; WBGene00007328 .
    GeneIDi 182251.
    KEGGi cel:CELE_C05C10.1.
    UCSCi C05C10.1. c. elegans.

    Organism-specific databases

    CTDi 182251.
    WormBasei C05C10.1 ; CE42840 ; WBGene00007328 ; pho-10.

    Phylogenomic databases

    eggNOGi NOG85977.
    GeneTreei ENSGT00530000062956.
    HOGENOMi HOG000016204.
    InParanoidi Q09448.
    KOi K01078.
    PhylomeDBi Q09448.

    Miscellaneous databases

    NextBioi 916916.

    Family and domain databases

    Gene3Di 3.40.50.1240. 1 hit.
    InterProi IPR000560. His_Pase_superF_clade-2.
    IPR029033. His_PPase_superfam.
    [Graphical view ]
    Pfami PF00328. His_Phos_2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53254. SSF53254. 1 hit.
    PROSITEi PS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
    PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      The C. elegans sequencing consortium
      Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2.

    Entry informationi

    Entry nameiPHO10_CAEEL
    AccessioniPrimary (citable) accession number: Q09448
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: January 20, 2009
    Last modified: October 1, 2014
    This is version 81 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programCaenorhabditis annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Caenorhabditis elegans
      Caenorhabditis elegans: entries, gene names and cross-references to WormBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3