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Protein

Putative acid phosphatase 10

Gene

pho-10

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei33NucleophileBy similarity1
Active sitei313Proton donorBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

ReactomeiR-CEL-6798695. Neutrophil degranulation.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative acid phosphatase 10 (EC:3.1.3.2)
Gene namesi
Name:pho-10
ORF Names:C05C10.1
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiC05C10.1; CE42840; WBGene00007328; pho-10.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001144681 – 411Putative acid phosphatase 10Add BLAST411

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi379 ↔ 385By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ09448.

Expressioni

Gene expression databases

BgeeiWBGene00007328.

Interactioni

Protein-protein interaction databases

STRINGi6239.C05C10.1.

Structurei

3D structure databases

ProteinModelPortaliQ09448.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the histidine acid phosphatase family.Curated

Phylogenomic databases

eggNOGiKOG3720. Eukaryota.
ENOG410ZVBQ. LUCA.
GeneTreeiENSGT00530000062956.
HOGENOMiHOG000016204.
InParanoidiQ09448.
KOiK14410.
OrthoDBiEOG093714GO.
PhylomeDBiQ09448.

Family and domain databases

CDDicd07061. HP_HAP_like. 1 hit.
Gene3Di3.40.50.1240. 1 hit.
InterProiView protein in InterPro
IPR033379. Acid_Pase_AS.
IPR000560. His_Pase_clade-2.
IPR029033. His_PPase_superfam.
PfamiView protein in Pfam
PF00328. His_Phos_2. 1 hit.
SUPFAMiSSF53254. SSF53254. 1 hit.
PROSITEiView protein in PROSITE
PS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q09448-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLSLFCVII VAVGCSSKDG NVKLEFVQAM WRHGERSALA DLYPIYEKDW
60 70 80 90 100
VFGGGGLGEL TGRGMGEMNN LGRLIRERYV RKFNFLEPKY ASKEVYFRST
110 120 130 140 150
NLNRTIISAM SLLYGLFPPS LYDIPNVDYP FTPLKWLPGL AFVPVHVDGS
160 170 180 190 200
DQCAASQNCP CPRYDFLQQQ MLTLPEVQQA FQQVILLNRQ IAPLYNVTTG
210 220 230 240 250
VDTFYVYPDT WKCQRAYFNK TMYDKLPWYN EQLYSKAEIT YAPIKGFLEG
260 270 280 290 300
SFSQPAVTSN GLDVAFEIQQ VRSGVMINEI VSRASEKLNC VERGQNCTSY
310 320 330 340 350
LNKLKFYGYS IHDNNVYAVL VALGIPHISA TEDGWPSYAA AIFFEFYRNS
360 370 380 390 400
QTNKRLFKVL YRQDASSQIT DVTSQVPMCQ GVSMCPLSTF QHLADVLKPI
410
PDINTVCNIT S
Length:411
Mass (Da):46,600
Last modified:January 20, 2009 - v2
Checksum:iA18761D5232B00C3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z48178 Genomic DNA. Translation: CAA88204.2.
PIRiT18944.
RefSeqiNP_496140.2. NM_063739.2.
UniGeneiCel.25704.

Genome annotation databases

EnsemblMetazoaiC05C10.1; C05C10.1; WBGene00007328.
GeneIDi182251.
KEGGicel:CELE_C05C10.1.
UCSCiC05C10.1. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiPHO10_CAEEL
AccessioniPrimary (citable) accession number: Q09448
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: January 20, 2009
Last modified: August 30, 2017
This is version 95 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families