Q09448 (PHO10_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative acid phosphatase 10
EC=3.1.3.2

Gene names

Name:	pho-10
ORF Names:	C05C10.1

Organism

Caenorhabditis elegans [Reference proteome]

Taxonomic identifier

6239 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	411 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	A phosphate monoester + H2O = an alcohol + phosphate.
Sequence similarities	Belongs to the histidine acid phosphatase family.

Ontologies

Keywords
Molecular function	Hydrolase
PTM	Disulfide bond
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	acid phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 411	411	Putative acid phosphatase 10		PRO_0000114468
Sites
	Active site	33	1	Nucleophile By similarity
	Active site	313	1	Proton donor By similarity
Amino acid modifications
	Disulfide bond	379 ↔ 385		By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q09448 [UniParc]. Last modified January 20, 2009. Version 2. Checksum: A18761D5232B00C3	FASTA	411	46,600
	10 20 30 40 50 60 MFLSLFCVII VAVGCSSKDG NVKLEFVQAM WRHGERSALA DLYPIYEKDW VFGGGGLGEL 70 80 90 100 110 120 TGRGMGEMNN LGRLIRERYV RKFNFLEPKY ASKEVYFRST NLNRTIISAM SLLYGLFPPS 130 140 150 160 170 180 LYDIPNVDYP FTPLKWLPGL AFVPVHVDGS DQCAASQNCP CPRYDFLQQQ MLTLPEVQQA 190 200 210 220 230 240 FQQVILLNRQ IAPLYNVTTG VDTFYVYPDT WKCQRAYFNK TMYDKLPWYN EQLYSKAEIT 250 260 270 280 290 300 YAPIKGFLEG SFSQPAVTSN GLDVAFEIQQ VRSGVMINEI VSRASEKLNC VERGQNCTSY 310 320 330 340 350 360 LNKLKFYGYS IHDNNVYAVL VALGIPHISA TEDGWPSYAA AIFFEFYRNS QTNKRLFKVL 370 380 390 400 410 YRQDASSQIT DVTSQVPMCQ GVSMCPLSTF QHLADVLKPI PDINTVCNIT S

References

[1]	"Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z48178 Genomic DNA. Translation: CAA88204.2.
PIR	T18944.
RefSeq	NP_496140.2. NM_063739.2.
UniGene	Cel.25704.
3D structure databases
ProteinModelPortal	Q09448.
SMR	Q09448. Positions 23-399.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	C05C10.1; C05C10.1; C05C10.1.
GeneID	182251.
KEGG	cel:CELE_C05C10.1.
UCSC	C05C10.1. c. elegans.
Organism-specific databases
CTD	182251.
WormBase	C05C10.1; CE42840; WBGene00007328; pho-10.
Phylogenomic databases
eggNOG	NOG85977.
GeneTree	ENSGT00530000062956.
HOGENOM	HOG000016204.
InParanoid	Q09448.
KO	K01078.
Family and domain databases
InterPro	IPR000560. His_Pase_superF_clade-2. [Graphical view]
Pfam	PF00328. His_Phos_2. 1 hit. [Graphical view]
PROSITE	PS00616. HIS_ACID_PHOSPHAT_1. 1 hit. PS00778. HIS_ACID_PHOSPHAT_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	916916.

Entry information

Entry name

PHO10_CAEEL

Accession

Primary (citable) accession number: Q09448

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	January 20, 2009
Last modified:	May 1, 2013
This is version 75 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Caenorhabditis annotation project