Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q09422 (PGAM5_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine-protein phosphatase Pgam5, mitochondrial

EC=3.1.3.16
Alternative name(s):
Phosphoglycerate mutase family member 5 homolog
Gene names
Name:pgam-5
ORF Names:R07G3.5
OrganismCaenorhabditis elegans [Reference proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length284 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Displays phosphatase activity for serine/threonine residues. Has apparently no phosphoglycerate mutase activity By similarity.

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Subcellular location

Mitochondrion outer membrane; Single-pass membrane protein By similarity.

Sequence similarities

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 284284Serine/threonine-protein phosphatase Pgam5, mitochondrial
PRO_0000065425

Regions

Transmembrane8 – 2417Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q09422 [UniParc].

Last modified April 4, 2003. Version 2.
Checksum: 820D56CE79E71F90

FASTA28432,490
        10         20         30         40         50         60 
MVSKIIKLGV PTATLAVGTL LLGDDEKRSA FFRTASAFTQ NHGHKTFDEH FPRGEWDKNW 

        70         80         90        100        110        120 
DFRDPISLVD KGKWEKADEE GKKKLIEEKK ATATRNIFLI RHGQYHLDHE VKMLTPLGRE 

       130        140        150        160        170        180 
QAELLGKRLA NSDIKFTNMT MSTMVRATET ANIILKHLPD DLTRTSSPFI EEGPPYPPVP 

       190        200        210        220        230        240 
DHKTWRPLDP EFYTEAARIE SAYRKIFHRA SPSQKEDSFE LIVCHANVIR YFICRALQFP 

       250        260        270        280 
PEGWLRMSLG NCSLTWITIR PKGHVSVRSI GDIGHLPPNK ISFT 

« Hide

References

[1]"Genome sequence of the nematode C. elegans: a platform for investigating biology."
The C. elegans sequencing consortium
Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Bristol N2.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FO081291 Genomic DNA. Translation: CCD70516.1.
PIRT16702.
RefSeqNP_495593.2. NM_063192.4.
UniGeneCel.5727.

3D structure databases

ProteinModelPortalQ09422.
SMRQ09422. Positions 86-282.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING6239.R07G3.5.

Proteomic databases

PaxDbQ09422.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaR07G3.5; R07G3.5; WBGene00019941.
GeneID174231.
KEGGcel:CELE_R07G3.5.
UCSCR07G3.5. c. elegans.

Organism-specific databases

CTD174231.
WormBaseR07G3.5; CE31979; WBGene00019941; pgam-5.

Phylogenomic databases

eggNOGNOG71348.
GeneTreeENSGT00390000004796.
HOGENOMHOG000261217.
InParanoidQ09422.
KOK15637.
OMAWLRMSLN.
PhylomeDBQ09422.

Family and domain databases

Gene3D3.40.50.1240. 1 hit.
InterProIPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
[Graphical view]
PfamPF00300. His_Phos_1. 1 hit.
[Graphical view]
SMARTSM00855. PGAM. 1 hit.
[Graphical view]
SUPFAMSSF53254. SSF53254. 1 hit.
ProtoNetSearch...

Other

NextBio883113.
PROQ09422.

Entry information

Entry namePGAM5_CAEEL
AccessionPrimary (citable) accession number: Q09422
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: April 4, 2003
Last modified: June 11, 2014
This is version 80 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormBase