Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Serine/threonine-protein phosphatase Pgam5, mitochondrial

Gene

pgam-5

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Displays phosphatase activity for serine/threonine residues. Has apparently no phosphoglycerate mutase activity (By similarity).By similarity

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

GO - Molecular functioni

  1. phosphoprotein phosphatase activity Source: UniProtKB

GO - Biological processi

  1. protein dephosphorylation Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase Pgam5, mitochondrial (EC:3.1.3.16)
Alternative name(s):
Phosphoglycerate mutase family member 5 homolog
Gene namesi
Name:pgam-5
ORF Names:R07G3.5
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome II

Organism-specific databases

WormBaseiR07G3.5; CE31979; WBGene00019941; pgam-5.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei8 – 2417HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial outer membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion outer membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 284284Serine/threonine-protein phosphatase Pgam5, mitochondrialPRO_0000065425Add
BLAST

Proteomic databases

PaxDbiQ09422.

Interactioni

Protein-protein interaction databases

STRINGi6239.R07G3.5.

Structurei

3D structure databases

ProteinModelPortaliQ09422.
SMRiQ09422. Positions 86-282.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG71348.
GeneTreeiENSGT00390000004796.
HOGENOMiHOG000261217.
InParanoidiQ09422.
KOiK15637.
OMAiEIIVCHA.
PhylomeDBiQ09422.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
InterProiIPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
[Graphical view]
PfamiPF00300. His_Phos_1. 1 hit.
[Graphical view]
SMARTiSM00855. PGAM. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.

Sequencei

Sequence statusi: Complete.

Q09422-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVSKIIKLGV PTATLAVGTL LLGDDEKRSA FFRTASAFTQ NHGHKTFDEH
60 70 80 90 100
FPRGEWDKNW DFRDPISLVD KGKWEKADEE GKKKLIEEKK ATATRNIFLI
110 120 130 140 150
RHGQYHLDHE VKMLTPLGRE QAELLGKRLA NSDIKFTNMT MSTMVRATET
160 170 180 190 200
ANIILKHLPD DLTRTSSPFI EEGPPYPPVP DHKTWRPLDP EFYTEAARIE
210 220 230 240 250
SAYRKIFHRA SPSQKEDSFE LIVCHANVIR YFICRALQFP PEGWLRMSLG
260 270 280
NCSLTWITIR PKGHVSVRSI GDIGHLPPNK ISFT
Length:284
Mass (Da):32,490
Last modified:April 4, 2003 - v2
Checksum:i820D56CE79E71F90
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO081291 Genomic DNA. Translation: CCD70516.1.
PIRiT16702.
RefSeqiNP_495593.2. NM_063192.4.
UniGeneiCel.5727.

Genome annotation databases

EnsemblMetazoaiR07G3.5; R07G3.5; WBGene00019941.
GeneIDi174231.
KEGGicel:CELE_R07G3.5.
UCSCiR07G3.5. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO081291 Genomic DNA. Translation: CCD70516.1.
PIRiT16702.
RefSeqiNP_495593.2. NM_063192.4.
UniGeneiCel.5727.

3D structure databases

ProteinModelPortaliQ09422.
SMRiQ09422. Positions 86-282.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.R07G3.5.

Proteomic databases

PaxDbiQ09422.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiR07G3.5; R07G3.5; WBGene00019941.
GeneIDi174231.
KEGGicel:CELE_R07G3.5.
UCSCiR07G3.5. c. elegans.

Organism-specific databases

CTDi174231.
WormBaseiR07G3.5; CE31979; WBGene00019941; pgam-5.

Phylogenomic databases

eggNOGiNOG71348.
GeneTreeiENSGT00390000004796.
HOGENOMiHOG000261217.
InParanoidiQ09422.
KOiK15637.
OMAiEIIVCHA.
PhylomeDBiQ09422.

Miscellaneous databases

NextBioi883113.
PROiQ09422.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
InterProiIPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
[Graphical view]
PfamiPF00300. His_Phos_1. 1 hit.
[Graphical view]
SMARTiSM00855. PGAM. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiPGAM5_CAEEL
AccessioniPrimary (citable) accession number: Q09422
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: April 4, 2003
Last modified: January 7, 2015
This is version 83 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.