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Q09422

- PGAM5_CAEEL

UniProt

Q09422 - PGAM5_CAEEL

Protein

Serine/threonine-protein phosphatase Pgam5, mitochondrial

Gene

pgam-5

Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 2 (04 Apr 2003)
      Previous versions | rss
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    Functioni

    Displays phosphatase activity for serine/threonine residues. Has apparently no phosphoglycerate mutase activity By similarity.By similarity

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    GO - Molecular functioni

    1. phosphoprotein phosphatase activity Source: UniProtKB

    GO - Biological processi

    1. protein dephosphorylation Source: UniProtKB

    Keywords - Molecular functioni

    Hydrolase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Serine/threonine-protein phosphatase Pgam5, mitochondrial (EC:3.1.3.16)
    Alternative name(s):
    Phosphoglycerate mutase family member 5 homolog
    Gene namesi
    Name:pgam-5
    ORF Names:R07G3.5
    OrganismiCaenorhabditis elegans
    Taxonomic identifieri6239 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000001940: Chromosome II

    Organism-specific databases

    WormBaseiR07G3.5; CE31979; WBGene00019941; pgam-5.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. mitochondrial outer membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion outer membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 284284Serine/threonine-protein phosphatase Pgam5, mitochondrialPRO_0000065425Add
    BLAST

    Proteomic databases

    PaxDbiQ09422.

    Interactioni

    Protein-protein interaction databases

    STRINGi6239.R07G3.5.

    Structurei

    3D structure databases

    ProteinModelPortaliQ09422.
    SMRiQ09422. Positions 86-282.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei8 – 2417HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG71348.
    GeneTreeiENSGT00390000004796.
    HOGENOMiHOG000261217.
    InParanoidiQ09422.
    KOiK15637.
    OMAiWLRMSLN.
    PhylomeDBiQ09422.

    Family and domain databases

    Gene3Di3.40.50.1240. 1 hit.
    InterProiIPR013078. His_Pase_superF_clade-1.
    IPR029033. His_PPase_superfam.
    [Graphical view]
    PfamiPF00300. His_Phos_1. 1 hit.
    [Graphical view]
    SMARTiSM00855. PGAM. 1 hit.
    [Graphical view]
    SUPFAMiSSF53254. SSF53254. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q09422-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVSKIIKLGV PTATLAVGTL LLGDDEKRSA FFRTASAFTQ NHGHKTFDEH    50
    FPRGEWDKNW DFRDPISLVD KGKWEKADEE GKKKLIEEKK ATATRNIFLI 100
    RHGQYHLDHE VKMLTPLGRE QAELLGKRLA NSDIKFTNMT MSTMVRATET 150
    ANIILKHLPD DLTRTSSPFI EEGPPYPPVP DHKTWRPLDP EFYTEAARIE 200
    SAYRKIFHRA SPSQKEDSFE LIVCHANVIR YFICRALQFP PEGWLRMSLG 250
    NCSLTWITIR PKGHVSVRSI GDIGHLPPNK ISFT 284
    Length:284
    Mass (Da):32,490
    Last modified:April 4, 2003 - v2
    Checksum:i820D56CE79E71F90
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FO081291 Genomic DNA. Translation: CCD70516.1.
    PIRiT16702.
    RefSeqiNP_495593.2. NM_063192.4.
    UniGeneiCel.5727.

    Genome annotation databases

    EnsemblMetazoaiR07G3.5; R07G3.5; WBGene00019941.
    GeneIDi174231.
    KEGGicel:CELE_R07G3.5.
    UCSCiR07G3.5. c. elegans.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FO081291 Genomic DNA. Translation: CCD70516.1 .
    PIRi T16702.
    RefSeqi NP_495593.2. NM_063192.4.
    UniGenei Cel.5727.

    3D structure databases

    ProteinModelPortali Q09422.
    SMRi Q09422. Positions 86-282.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 6239.R07G3.5.

    Proteomic databases

    PaxDbi Q09422.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai R07G3.5 ; R07G3.5 ; WBGene00019941 .
    GeneIDi 174231.
    KEGGi cel:CELE_R07G3.5.
    UCSCi R07G3.5. c. elegans.

    Organism-specific databases

    CTDi 174231.
    WormBasei R07G3.5 ; CE31979 ; WBGene00019941 ; pgam-5.

    Phylogenomic databases

    eggNOGi NOG71348.
    GeneTreei ENSGT00390000004796.
    HOGENOMi HOG000261217.
    InParanoidi Q09422.
    KOi K15637.
    OMAi WLRMSLN.
    PhylomeDBi Q09422.

    Miscellaneous databases

    NextBioi 883113.
    PROi Q09422.

    Family and domain databases

    Gene3Di 3.40.50.1240. 1 hit.
    InterProi IPR013078. His_Pase_superF_clade-1.
    IPR029033. His_PPase_superfam.
    [Graphical view ]
    Pfami PF00300. His_Phos_1. 1 hit.
    [Graphical view ]
    SMARTi SM00855. PGAM. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53254. SSF53254. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      The C. elegans sequencing consortium
      Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2.

    Entry informationi

    Entry nameiPGAM5_CAEEL
    AccessioniPrimary (citable) accession number: Q09422
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: April 4, 2003
    Last modified: October 1, 2014
    This is version 81 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programCaenorhabditis annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Caenorhabditis elegans
      Caenorhabditis elegans: entries, gene names and cross-references to WormBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3