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Q09422

- PGAM5_CAEEL

UniProt

Q09422 - PGAM5_CAEEL

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Protein

Serine/threonine-protein phosphatase Pgam5, mitochondrial

Gene
pgam-5, R07G3.5
Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Displays phosphatase activity for serine/threonine residues. Has apparently no phosphoglycerate mutase activity By similarity.

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

GO - Molecular functioni

  1. phosphoprotein phosphatase activity Source: UniProtKB

GO - Biological processi

  1. protein dephosphorylation Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase Pgam5, mitochondrial (EC:3.1.3.16)
Alternative name(s):
Phosphoglycerate mutase family member 5 homolog
Gene namesi
Name:pgam-5
ORF Names:R07G3.5
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome II

Organism-specific databases

WormBaseiR07G3.5; CE31979; WBGene00019941; pgam-5.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei8 – 2417Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial outer membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion outer membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 284284Serine/threonine-protein phosphatase Pgam5, mitochondrialPRO_0000065425Add
BLAST

Proteomic databases

PaxDbiQ09422.

Interactioni

Protein-protein interaction databases

STRINGi6239.R07G3.5.

Structurei

3D structure databases

ProteinModelPortaliQ09422.
SMRiQ09422. Positions 86-282.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG71348.
GeneTreeiENSGT00390000004796.
HOGENOMiHOG000261217.
InParanoidiQ09422.
KOiK15637.
OMAiWLRMSLN.
PhylomeDBiQ09422.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
InterProiIPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
[Graphical view]
PfamiPF00300. His_Phos_1. 1 hit.
[Graphical view]
SMARTiSM00855. PGAM. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.

Sequencei

Sequence statusi: Complete.

Q09422-1 [UniParc]FASTAAdd to Basket

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MVSKIIKLGV PTATLAVGTL LLGDDEKRSA FFRTASAFTQ NHGHKTFDEH    50
FPRGEWDKNW DFRDPISLVD KGKWEKADEE GKKKLIEEKK ATATRNIFLI 100
RHGQYHLDHE VKMLTPLGRE QAELLGKRLA NSDIKFTNMT MSTMVRATET 150
ANIILKHLPD DLTRTSSPFI EEGPPYPPVP DHKTWRPLDP EFYTEAARIE 200
SAYRKIFHRA SPSQKEDSFE LIVCHANVIR YFICRALQFP PEGWLRMSLG 250
NCSLTWITIR PKGHVSVRSI GDIGHLPPNK ISFT 284
Length:284
Mass (Da):32,490
Last modified:April 4, 2003 - v2
Checksum:i820D56CE79E71F90
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FO081291 Genomic DNA. Translation: CCD70516.1.
PIRiT16702.
RefSeqiNP_495593.2. NM_063192.4.
UniGeneiCel.5727.

Genome annotation databases

EnsemblMetazoaiR07G3.5; R07G3.5; WBGene00019941.
GeneIDi174231.
KEGGicel:CELE_R07G3.5.
UCSCiR07G3.5. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FO081291 Genomic DNA. Translation: CCD70516.1 .
PIRi T16702.
RefSeqi NP_495593.2. NM_063192.4.
UniGenei Cel.5727.

3D structure databases

ProteinModelPortali Q09422.
SMRi Q09422. Positions 86-282.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 6239.R07G3.5.

Proteomic databases

PaxDbi Q09422.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai R07G3.5 ; R07G3.5 ; WBGene00019941 .
GeneIDi 174231.
KEGGi cel:CELE_R07G3.5.
UCSCi R07G3.5. c. elegans.

Organism-specific databases

CTDi 174231.
WormBasei R07G3.5 ; CE31979 ; WBGene00019941 ; pgam-5.

Phylogenomic databases

eggNOGi NOG71348.
GeneTreei ENSGT00390000004796.
HOGENOMi HOG000261217.
InParanoidi Q09422.
KOi K15637.
OMAi WLRMSLN.
PhylomeDBi Q09422.

Miscellaneous databases

NextBioi 883113.
PROi Q09422.

Family and domain databases

Gene3Di 3.40.50.1240. 1 hit.
InterProi IPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
[Graphical view ]
Pfami PF00300. His_Phos_1. 1 hit.
[Graphical view ]
SMARTi SM00855. PGAM. 1 hit.
[Graphical view ]
SUPFAMi SSF53254. SSF53254. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiPGAM5_CAEEL
AccessioniPrimary (citable) accession number: Q09422
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: April 4, 2003
Last modified: June 11, 2014
This is version 80 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi