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Protein

Proteasomal ubiquitin receptor ADRM1 homolog

Gene

C56G2.7

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

May function as a proteasomal ubiquitin receptor. May promote the deubiquitinating activity associated with the 26S proteasome (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-CEL-5689603. UCH proteinases.
R-CEL-5689880. Ub-specific processing proteases.

Names & Taxonomyi

Protein namesi
Recommended name:
Proteasomal ubiquitin receptor ADRM1 homolog
Gene namesi
ORF Names:C56G2.7
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiC56G2.7; CE30640; WBGene00016981.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm, Nucleus, Proteasome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000652571 – 374Proteasomal ubiquitin receptor ADRM1 homologAdd BLAST374

Proteomic databases

EPDiQ09289.
PaxDbiQ09289.
PeptideAtlasiQ09289.
PRIDEiQ09289.

PTM databases

iPTMnetiQ09289.

Expressioni

Gene expression databases

BgeeiWBGene00016981.

Interactioni

Subunit structurei

Interacts with the 26S proteasome.

GO - Molecular functioni

Protein-protein interaction databases

BioGridi533206. 1 interactor.
IntActiQ09289. 5 interactors.
MINTiMINT-1045435.
STRINGi6239.C56G2.7.1.

Structurei

3D structure databases

ProteinModelPortaliQ09289.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini17 – 130PHAdd BLAST114

Domaini

The PH domain mediates interactions with PSMD1 and ubiquitin. Preferential binding to the proximal subunit of K48-linked diubiquitin allows UCHL5 access to the distal subunit (By similarity).By similarity

Sequence similaritiesi

Belongs to the ADRM1 family.Curated

Phylogenomic databases

eggNOGiKOG3037. Eukaryota.
ENOG410XSJJ. LUCA.
GeneTreeiENSGT00390000013839.
HOGENOMiHOG000005947.
InParanoidiQ09289.
KOiK06691.
OMAiGKMVHPD.
OrthoDBiEOG091G0FEO.
PhylomeDBiQ09289.

Family and domain databases

InterProiView protein in InterPro
IPR006773. 26S_Psome_Ubiquitin-recp_Rpn13.
IPR032368. RPN13_C.
PANTHERiPTHR12225. PTHR12225. 1 hit.
PfamiView protein in Pfam
PF04683. Proteasom_Rpn13. 1 hit.
PF16550. RPN13_C. 1 hit.

Sequencei

Sequence statusi: Complete.

Q09289-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAMFSNTRS VASSSGHIVE FKAGRSRLEA GSGDTMRKVV AEPKKGLVFI
60 70 80 90 100
KQSNDMLIHF CWKDRETGAV VDDLIIFPDD AEFKAVPGCP DGKVYMLKFK
110 120 130 140 150
SGDMKLFWIQ DSTPDVDKDL VKKVTDALNK PPTSRPAASR SAGSNANTDR
160 170 180 190 200
QSAGGSLISS SDMNAPLGGI DQGQLMSLIQ SLQGGNSDTL PISSVPRGED
210 220 230 240 250
ASSEADCEPS TNAAEEGSSN PLSLNNPAIQ QIFNNLGRSQ KKEVAVSLAT
260 270 280 290 300
ALSNETVAEV ARNHAEELAP HLPTSDDPAR ELSETVRTPQ FRQAADTLGH
310 320 330 340 350
ALQTGQLGPV VAQFGMDEAT VGSANQGDIR GFAANLTKAE GGEDAAKTQN
360 370
SDDDATREPE PKRNRPDNED MDVD
Length:374
Mass (Da):39,773
Last modified:June 20, 2002 - v2
Checksum:iFD37CFC6EB991044
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080744 Genomic DNA. Translation: CCD66338.1.
RefSeqiNP_498387.2. NM_065986.6.
UniGeneiCel.20046.

Genome annotation databases

EnsemblMetazoaiC56G2.7; C56G2.7; WBGene00016981.
GeneIDi3565888.
KEGGicel:CELE_C56G2.7.
UCSCiC56G2.7. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080744 Genomic DNA. Translation: CCD66338.1.
RefSeqiNP_498387.2. NM_065986.6.
UniGeneiCel.20046.

3D structure databases

ProteinModelPortaliQ09289.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi533206. 1 interactor.
IntActiQ09289. 5 interactors.
MINTiMINT-1045435.
STRINGi6239.C56G2.7.1.

PTM databases

iPTMnetiQ09289.

Proteomic databases

EPDiQ09289.
PaxDbiQ09289.
PeptideAtlasiQ09289.
PRIDEiQ09289.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC56G2.7; C56G2.7; WBGene00016981.
GeneIDi3565888.
KEGGicel:CELE_C56G2.7.
UCSCiC56G2.7. c. elegans.

Organism-specific databases

CTDi3565888.
WormBaseiC56G2.7; CE30640; WBGene00016981.

Phylogenomic databases

eggNOGiKOG3037. Eukaryota.
ENOG410XSJJ. LUCA.
GeneTreeiENSGT00390000013839.
HOGENOMiHOG000005947.
InParanoidiQ09289.
KOiK06691.
OMAiGKMVHPD.
OrthoDBiEOG091G0FEO.
PhylomeDBiQ09289.

Enzyme and pathway databases

ReactomeiR-CEL-5689603. UCH proteinases.
R-CEL-5689880. Ub-specific processing proteases.

Miscellaneous databases

PROiPR:Q09289.

Gene expression databases

BgeeiWBGene00016981.

Family and domain databases

InterProiView protein in InterPro
IPR006773. 26S_Psome_Ubiquitin-recp_Rpn13.
IPR032368. RPN13_C.
PANTHERiPTHR12225. PTHR12225. 1 hit.
PfamiView protein in Pfam
PF04683. Proteasom_Rpn13. 1 hit.
PF16550. RPN13_C. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiADRM1_CAEEL
AccessioniPrimary (citable) accession number: Q09289
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: June 20, 2002
Last modified: June 7, 2017
This is version 111 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.