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Protein

Fatty acid-binding protein, brain

Gene

FABP7

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

FABP are thought to play a role in the intracellular transport of long chain fatty acids and their acyl-CoA esters. Binds oleic and palmitic acids but not palmitoyl CoA.2 Publications

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport
LigandLipid-binding

Enzyme and pathway databases

ReactomeiR-BTA-163560 Triglyceride catabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Fatty acid-binding protein, brain
Alternative name(s):
Brain-type fatty acid-binding protein
Short name:
B-FABP
Fatty acid-binding protein 7
Gene namesi
Name:FABP7
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 9

Organism-specific databases

VGNCiVGNC:28699 FABP7

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved
ChainiPRO_00000673722 – 132Fatty acid-binding protein, brainAdd BLAST131

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylvaline1 Publication1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ09139
PeptideAtlasiQ09139
PRIDEiQ09139

Expressioni

Gene expression databases

BgeeiENSBTAG00000033803

Interactioni

Subunit structurei

Monomer.2 Publications

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000017593

Structurei

3D structure databases

ProteinModelPortaliQ09139
SMRiQ09139
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni127 – 129Fatty acid bindingBy similarity3

Domaini

Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG4015 Eukaryota
ENOG4111US8 LUCA
GeneTreeiENSGT00760000118898
HOGENOMiHOG000004829
HOVERGENiHBG005633
InParanoidiQ09139
KOiK08756
OMAiVCTRIYK
OrthoDBiEOG091G0QSV
TreeFamiTF316894

Family and domain databases

Gene3Di2.40.128.20, 1 hit
InterProiView protein in InterPro
IPR012674 Calycin
IPR000463 Fatty_acid-bd
IPR031259 ILBP
IPR000566 Lipocln_cytosolic_FA-bd_dom
PANTHERiPTHR11955 PTHR11955, 1 hit
PfamiView protein in Pfam
PF00061 Lipocalin, 1 hit
PRINTSiPR00178 FATTYACIDBP
SUPFAMiSSF50814 SSF50814, 1 hit
PROSITEiView protein in PROSITE
PS00214 FABP, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q09139-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVEAFCATWK LTESQNFDEY MKALGVGFAT RQVGNVTKPT VIISQEGDRV
60 70 80 90 100
VIRTQSTFKN TEISFHLGEE FDETTADDRN CKSVVSLDGD KLVHVQKWDG
110 120 130
KETNFVREIK DGKMIMTLTF GDVVAVRHYE KA
Length:132
Mass (Da):14,956
Last modified:February 5, 2008 - v2
Checksum:i0FB37FC72C150517
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC118369 mRNA Translation: AAI18370.1
PIRiS06479
RefSeqiNP_001071630.1, NM_001078162.2
UniGeneiBt.2892

Genome annotation databases

EnsembliENSBTAT00000017593; ENSBTAP00000017593; ENSBTAG00000033803
GeneIDi777787
KEGGibta:777787

Similar proteinsi

Entry informationi

Entry nameiFABP7_BOVIN
AccessioniPrimary (citable) accession number: Q09139
Secondary accession number(s): Q17QG9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: February 5, 2008
Last modified: March 28, 2018
This is version 107 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

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