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Protein

60S ribosomal protein L10-A

Gene

rpl1001

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-SPO-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-SPO-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-SPO-72689. Formation of a pool of free 40S subunits.
R-SPO-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-SPO-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-SPO-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L10-A
Alternative name(s):
QM protein homolog
SpQM
Gene namesi
Name:rpl1001
Synonyms:rpl10, rpl10a
ORF Names:SPBC18E5.04
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC18E5.04.
PomBaseiSPBC18E5.04. rpl1001.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: PomBase
  • cytosolic large ribosomal subunit Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 22122160S ribosomal protein L10-APRO_0000147127Add
BLAST

Proteomic databases

PRIDEiQ09127.

Interactioni

Subunit structurei

Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S) (By similarity).By similarity

Protein-protein interaction databases

BioGridi277314. 4 interactions.
MINTiMINT-4693596.

Structurei

3D structure databases

ProteinModelPortaliQ09127.
SMRiQ09127. Positions 4-169.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L10e family.Curated

Phylogenomic databases

HOGENOMiHOG000223754.
InParanoidiQ09127.
KOiK02866.
OMAiLISKEWE.
OrthoDBiEOG092C4HB9.
PhylomeDBiQ09127.

Family and domain databases

CDDicd01433. Ribosomal_L16_L10e. 1 hit.
Gene3Di3.90.1170.10. 1 hit.
InterProiIPR001197. Ribosomal_L10e.
IPR016180. Ribosomal_L10e/L16.
IPR018255. Ribosomal_L10e_CS.
[Graphical view]
PfamiPF00252. Ribosomal_L16. 1 hit.
[Graphical view]
PIRSFiPIRSF005590. Ribosomal_L10. 1 hit.
SUPFAMiSSF54686. SSF54686. 1 hit.
TIGRFAMsiTIGR00279. uL16_euk_arch. 1 hit.
PROSITEiPS01257. RIBOSOMAL_L10E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q09127-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARRPARCYR YCKNKPYPKS RYNRAVPDSK IRIFDLGRKR AGVDEFPLCI
60 70 80 90 100
HLVSNEYEQI TSEALEAARI CANKYLVKIG GKDSFHLRVR AHPFHVVRIN
110 120 130 140 150
KMLSCAGADR LQTGMRHAFG KPNGLVARVN IGQILMSVRT KDSSRATAIE
160 170 180 190 200
ALRRCQYKFP GQQRIIVSKK WGFSQYARDE YIEKRSRGEI IPDGCYAKFL
210 220
NKRGSLQEKL DLFPEASFNL A
Length:221
Mass (Da):25,373
Last modified:May 30, 2000 - v2
Checksum:i1014EA03C0EAAE88
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti221 – 2211A → LRLTCNNEQCVN in AAB03806 (PubMed:8621081).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U33214 mRNA. Translation: AAB03806.1.
CU329671 Genomic DNA. Translation: CAA22664.1.
PIRiJC4755.
RefSeqiNP_595850.1. NM_001021754.2.

Genome annotation databases

EnsemblFungiiSPBC18E5.04.1; SPBC18E5.04.1:pep; SPBC18E5.04.
GeneIDi2540795.
KEGGispo:SPBC18E5.04.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U33214 mRNA. Translation: AAB03806.1.
CU329671 Genomic DNA. Translation: CAA22664.1.
PIRiJC4755.
RefSeqiNP_595850.1. NM_001021754.2.

3D structure databases

ProteinModelPortaliQ09127.
SMRiQ09127. Positions 4-169.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi277314. 4 interactions.
MINTiMINT-4693596.

Proteomic databases

PRIDEiQ09127.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC18E5.04.1; SPBC18E5.04.1:pep; SPBC18E5.04.
GeneIDi2540795.
KEGGispo:SPBC18E5.04.

Organism-specific databases

EuPathDBiFungiDB:SPBC18E5.04.
PomBaseiSPBC18E5.04. rpl1001.

Phylogenomic databases

HOGENOMiHOG000223754.
InParanoidiQ09127.
KOiK02866.
OMAiLISKEWE.
OrthoDBiEOG092C4HB9.
PhylomeDBiQ09127.

Enzyme and pathway databases

ReactomeiR-SPO-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-SPO-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-SPO-72689. Formation of a pool of free 40S subunits.
R-SPO-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-SPO-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-SPO-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

PROiQ09127.

Family and domain databases

CDDicd01433. Ribosomal_L16_L10e. 1 hit.
Gene3Di3.90.1170.10. 1 hit.
InterProiIPR001197. Ribosomal_L10e.
IPR016180. Ribosomal_L10e/L16.
IPR018255. Ribosomal_L10e_CS.
[Graphical view]
PfamiPF00252. Ribosomal_L16. 1 hit.
[Graphical view]
PIRSFiPIRSF005590. Ribosomal_L10. 1 hit.
SUPFAMiSSF54686. SSF54686. 1 hit.
TIGRFAMsiTIGR00279. uL16_euk_arch. 1 hit.
PROSITEiPS01257. RIBOSOMAL_L10E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRL10A_SCHPO
AccessioniPrimary (citable) accession number: Q09127
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: May 30, 2000
Last modified: September 7, 2016
This is version 116 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

There are two genes for L10 in S.pombe.

Caution

Was originally thought to be a transcription factor that may bind Jun homologs such as GCN4 and YAP-1, and which may inhibit DNA binding and transactivation by Jun homologs.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.