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Protein

60S ribosomal protein L10-A

Gene

rpl1001

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Miscellaneous

There are two genes for L10 in S.pombe.

Caution

Was originally thought to be a transcription factor that may bind Jun homologs such as GCN4 and YAP-1, and which may inhibit DNA binding and transactivation by Jun homologs.1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-SPO-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-SPO-1799339 SRP-dependent cotranslational protein targeting to membrane
R-SPO-72689 Formation of a pool of free 40S subunits
R-SPO-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-SPO-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-SPO-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L10-A
Alternative name(s):
QM protein homolog
SpQM
Gene namesi
Name:rpl1001
Synonyms:rpl10, rpl10a
ORF Names:SPBC18E5.04
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC18E5.04
PomBaseiSPBC18E5.04 rpl1001

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001471271 – 22160S ribosomal protein L10-AAdd BLAST221

Proteomic databases

MaxQBiQ09127
PaxDbiQ09127
PRIDEiQ09127

PTM databases

iPTMnetiQ09127

Interactioni

Subunit structurei

Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S) (By similarity).By similarity

Protein-protein interaction databases

BioGridi277314, 1 interactor
STRINGi4896.SPBC18E5.04.1

Structurei

3D structure databases

ProteinModelPortaliQ09127
SMRiQ09127
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000223754
InParanoidiQ09127
KOiK02866
OMAiPYTRKEY
OrthoDBiEOG092C4HB9
PhylomeDBiQ09127

Family and domain databases

CDDicd01433 Ribosomal_L16_L10e, 1 hit
Gene3Di3.90.1170.10, 1 hit
InterProiView protein in InterPro
IPR001197 Ribosomal_L10e
IPR016180 Ribosomal_L10e/L16
IPR036920 Ribosomal_L10e/L16_sf
IPR018255 Ribosomal_L10e_CS
PANTHERiPTHR11726 PTHR11726, 1 hit
PfamiView protein in Pfam
PF00252 Ribosomal_L16, 1 hit
PIRSFiPIRSF005590 Ribosomal_L10, 1 hit
SUPFAMiSSF54686 SSF54686, 1 hit
TIGRFAMsiTIGR00279 uL16_euk_arch, 1 hit
PROSITEiView protein in PROSITE
PS01257 RIBOSOMAL_L10E, 1 hit

Sequencei

Sequence statusi: Complete.

Q09127-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARRPARCYR YCKNKPYPKS RYNRAVPDSK IRIFDLGRKR AGVDEFPLCI
60 70 80 90 100
HLVSNEYEQI TSEALEAARI CANKYLVKIG GKDSFHLRVR AHPFHVVRIN
110 120 130 140 150
KMLSCAGADR LQTGMRHAFG KPNGLVARVN IGQILMSVRT KDSSRATAIE
160 170 180 190 200
ALRRCQYKFP GQQRIIVSKK WGFSQYARDE YIEKRSRGEI IPDGCYAKFL
210 220
NKRGSLQEKL DLFPEASFNL A
Length:221
Mass (Da):25,373
Last modified:May 30, 2000 - v2
Checksum:i1014EA03C0EAAE88
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti221A → LRLTCNNEQCVN in AAB03806 (PubMed:8621081).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U33214 mRNA Translation: AAB03806.1
CU329671 Genomic DNA Translation: CAA22664.1
PIRiJC4755
RefSeqiNP_595850.1, NM_001021754.2

Genome annotation databases

EnsemblFungiiSPBC18E5.04.1; SPBC18E5.04.1:pep; SPBC18E5.04
GeneIDi2540795
KEGGispo:SPBC18E5.04

Similar proteinsi

Entry informationi

Entry nameiRL10A_SCHPO
AccessioniPrimary (citable) accession number: Q09127
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: May 30, 2000
Last modified: May 23, 2018
This is version 128 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families
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