Reviewed, UniProtKB/Swiss-Prot Q09103 (DGK2_DROME)

Names and origin

Protein names

Recommended name:
    Eye-specific diacylglycerol kinase
      Short name=DAG kinase 2
      Short name=Diglyceride kinase 2
      Short name=DGK 2
    EC=2.7.1.107
Alternative name(s):
    Retinal degeneration A protein

Gene names

Name:	rdgA
Synonyms:	DGK2
ORF Names:	CG34344

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1457 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Required for the maintenance of phospholipid turnover within the photoreceptor. Ref.1
Catalytic activity	ATP + 1,2-diacylglycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.
Subcellular location	Membrane; Peripheral membrane protein.
Tissue specificity	Expressed specifically in adult eye. Ref.1
Disruption phenotype	Flies exhibit photoreceptor cells that degenerate within a week after eclosion. Ref.1
Sequence similarities	Belongs to the eukaryotic diacylglycerol kinase family. Contains 4 ANK repeats. Contains 1 DAGKc domain. Contains 2 phorbol-ester/DAG-type zinc fingers.
Sequence caution	The sequence AAQ22428.1 differs from that shown. Reason: Miscellaneous discrepancy. Intron retention.

Ontologies

Keywords
Biological process	Sensory transduction Vision
Cellular component	Membrane
Coding sequence diversity	Alternative splicing
Domain	ANK repeat Repeat Zinc-finger
Ligand	ATP-binding Metal-binding Nucleotide-binding Zinc
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	actin filament organization Inferred from mutant phenotype. Source: FlyBase activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway Inferred from electronic annotation. Source: InterPro deactivation of rhodopsin mediated signaling Inferred from genetic interaction. Source: FlyBase intracellular signaling cascade Inferred from electronic annotation. Source: InterPro lipid phosphorylation Traceable author statement. Source: FlyBase phosphatidic acid biosynthetic process Traceable author statement. Source: FlyBase phosphoinositide biosynthetic process Traceable author statement. Source: FlyBase photoreceptor cell maintenance Traceable author statement. Source: FlyBase thermotaxis Inferred from direct assay. Source: FlyBase
Cellular component	extrinsic to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW diacylglycerol kinase activity Traceable author statement. Source: FlyBase zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform A (identifier: Q09103-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform B (identifier: Q09103-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-116: MQQQQQPSID...KQQSSSSASA → MPERSISQRD...EDIEMLDYDT
     117-564: Missing.
     1315-1315: S → SNKDRLFSFNEDVFGCGFS
     1445-1457: KQGTQPVDGWLDD → QERFMHLEKQTRI

Note: No experimental confirmation available.

Isoform C (identifier: Q09103-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-132: MQQQQQPSID...AGFLQVPLAA → MERLLHAVRE...SLGAWRRKRR
     133-565: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1457	1457	Eye-specific diacylglycerol kinase		PRO_0000218474
Regions
	Domain	808 – 944	137	DAGKc
	Repeat	1320 – 1349	30	ANK 1
	Repeat	1353 – 1382	30	ANK 2
	Repeat	1389 – 1418	30	ANK 3
	Repeat	1422 – 1451	30	ANK 4
	Zinc finger	591 – 641	51	Phorbol-ester/DAG-type 1
	Zinc finger	661 – 724	64	Phorbol-ester/DAG-type 2
	Compositional bias	2 – 6	5	Poly-Gln
	Compositional bias	24 – 39	16	Thr-rich
	Compositional bias	110 – 115	6	Poly-Ser
	Compositional bias	227 – 231	5	Poly-Glu
	Compositional bias	763 – 778	16	Gly-rich
Natural variations
	Alternative sequence	1 – 132	132	MQQQQ…VPLAA → MERLLHAVREEFQTEDEYET EVDDEGNVLHRSSISSCSSS SSSSNTSSSSDGSNSTASQP LSPSLPQPRRRLQRSDSFGS VGGGVAGGVAGSGATGAGGV RRFRRSSIGMQRKSAFRQRK LDSLGAWRRKRR in isoform C.		VSP_030265
	Alternative sequence	1 – 116	116	MQQQQ…SSASA → MPERSISQRDLDEIEIESDE EEEELEQGVGLSTRSRRNRR GASDSPAASRARNATNGIQN RGRERERERERERSRERFGG TNAADEARFYDDEEQRMEDD GEEDSDEDIEMLDYDT in isoform B.		VSP_030264
	Alternative sequence	117 – 564	448	Missing in isoform B.		VSP_030266
	Alternative sequence	133 – 565	433	Missing in isoform C.		VSP_030267
	Alternative sequence	1315	1	S → SNKDRLFSFNEDVFGCGFS in isoform B.		VSP_028732
	Alternative sequence	1445 – 1457	13	KQGTQ…GWLDD → QERFMHLEKQTRI in isoform B.		VSP_028733
Experimental info
	Sequence conflict	32	1	A → V in BAA04135. Ref.1
	Sequence conflict	208	1	S → T in BAA04135. Ref.1
	Sequence conflict	438	1	N → K in BAA04135. Ref.1
	Sequence conflict	565	1	R → RR in BAA04135. Ref.1
	Sequence conflict	667	1	K → N in BAA04135. Ref.1
	Sequence conflict	679 – 684	6	Missing in BAA04135. Ref.1
	Sequence conflict	778	1	G → GGG in BAA04135. Ref.1
	Sequence conflict	924	1	L → M in AAQ22428. Ref.5
	Sequence conflict	983	1	E → G in AAQ22428. Ref.5
	Sequence conflict	1128	1	I → N in AAQ22428. Ref.5

Sequences

	Sequence		Length	Mass (Da)
	Isoform A [UniParc]. Last modified June 21, 2005. Version 2. Checksum: 8F4E33E9C1B665D1	FASTA	1,457	160,142
	10 20 30 40 50 60 MQQQQQPSID QLPEPTASTS NSATTKPTIA TATTSTTTTS GNNFHQQLQA TTAATMQRLR 70 80 90 100 110 120 TTFTRSRTPT GAEMKMQNSL EVPKQVRSAS FDEMQLESQR ASSSLLKQQS SSSASADERS 130 140 150 160 170 180 SEAGFLQVPL AAHQQRSHSF DSATASAGSD DSGTFLEVPR RLKARRSSST KTPPPCIHCH 190 200 210 220 230 240 YLEEYERRMT AEQRYFIDHR ELTALSYSNT SSEASEDEDE VEGHNAEEEE EGSAAIEDAE 250 260 270 280 290 300 EETTEAATEE ADEDPRTEVE SEHDHDPDDD AALEMDIRIG NMSQGSSIEE SRARLPRQMR 310 320 330 340 350 360 RHTIGSSSVT SASEDEGLEG SDNGSPHFGN TLLPPQPTTP CGITFTLSPT NGDYPSPPHL 370 380 390 400 410 420 PLDPGSPPIS PCSSNSGRLP ALAPIISTPC SSADADDAGA AMGLPVRARR RSISRQEAIF 430 440 450 460 470 480 VEPTGNSLEN VSHEEVDNSN TKSSVDTADS LDEASTMATC GSPGAAGGSG ASSSHHNAFV 490 500 510 520 530 540 VRDIYLMVPD LKRDRAASVD SCFSKLSSNA KTEELQPSAD GCFLTVPNIN ATRSRSVDIV 550 560 570 580 590 600 LPTDEQARYK ALSMTGSTVT YADGRTASAS NSRRPIRIVP DWTENAVQGE HYWKPTSASG 610 620 630 640 650 660 DLCCLNEECI KSGQRMKCSA CQLVAHHNCI PFVNEKSTLA CKPTYRDVGI RQYREQTTTH 670 680 690 700 710 720 HHWVHRKLEK GKCKQCGKFF PMKQAVQSKL FGSKEIVALA CAWCHEIYHN KEACFNQAKI 730 740 750 760 770 780 GEECRLGNYA PIIVPPSWIV KLPTKGNFKS SIRVSNKNNA ASGSGGGGAG GGAGGGGGKS 790 800 810 820 830 840 KKQTQRRQKG KEEKKEPRAF IVKPIPSPEV IPVIVFINPK SGGNQGHKLL GKFQHLLNPR 850 860 870 880 890 900 QVFDLTQGGP KMGLDMFRKA PNLRVLACGG DGTVGWVLSV LDQIQPPLQP APAVGVLPLG 910 920 930 940 950 960 TGNDLARALG WGGGYTDEPI GKILREIGMS QCVLMDRWRV KVTPNDDVTD DHVDRSKPNV 970 980 990 1000 1010 1020 PLNVINNYFS FGVDAHIALE FHEAREAHPE RFNSRLRNKM YYGQMGGKDL ILRQYRNLSQ 1030 1040 1050 1060 1070 1080 WVTLECDGQD FTGKLRDAGC HAVLFLNIPS YGGGTHPWND SFGASKPSID DGLMEVVGLT 1090 1100 1110 1120 1130 1140 TYQLPMLQAG MHGTCICQCR KARIITKRTI PMQVDGEACR VKPSVIEIEL LNKALMLSKR 1150 1160 1170 1180 1190 1200 KHGRGDVQVN PLEKMQLHIL RVTMQQYEQY HYDKEMLRKL ANKLGQIEIE SQCDLEHVRN 1210 1220 1230 1240 1250 1260 MLNTKFEESI SYPKVSQDWC FIDSCTAEHY FRIDRAQEHL HYICDIAIDE LYILDHEAAT 1270 1280 1290 1300 1310 1320 MPQTPDQERS FAAFSQRQAQ NERRQMDQAQ GRGPGSTDED LQIGSKPIKV MKWKSPILEQ 1330 1340 1350 1360 1370 1380 TSDAILLAAQ SGDLNMLRAL HEQGYSLQSV NKNGQTALHF ACKYNHRDIV KYIIASATRR 1390 1400 1410 1420 1430 1440 LINMADKELG QTALHIAAEQ NRRDICVMLV AAGAHLDTLD SGGNTPMMVA FNKNANEIAT 1450 YLESKQGTQP VDGWLDD
	Isoform B. Checksum: 70B26B9A087A84F9	FASTA	1,027	115,579
	10 20 30 40 50 60 MPERSISQRD LDEIEIESDE EEEELEQGVG LSTRSRRNRR GASDSPAASR ARNATNGIQN 70 80 90 100 110 120 RGRERERERE RERSRERFGG TNAADEARFY DDEEQRMEDD GEEDSDEDIE MLDYDTRTAS 130 140 150 160 170 180 ASNSRRPIRI VPDWTENAVQ GEHYWKPTSA SGDLCCLNEE CIKSGQRMKC SACQLVAHHN 190 200 210 220 230 240 CIPFVNEKST LACKPTYRDV GIRQYREQTT THHHWVHRKL EKGKCKQCGK FFPMKQAVQS 250 260 270 280 290 300 KLFGSKEIVA LACAWCHEIY HNKEACFNQA KIGEECRLGN YAPIIVPPSW IVKLPTKGNF 310 320 330 340 350 360 KSSIRVSNKN NAASGSGGGG AGGGAGGGGG KSKKQTQRRQ KGKEEKKEPR AFIVKPIPSP 370 380 390 400 410 420 EVIPVIVFIN PKSGGNQGHK LLGKFQHLLN PRQVFDLTQG GPKMGLDMFR KAPNLRVLAC 430 440 450 460 470 480 GGDGTVGWVL SVLDQIQPPL QPAPAVGVLP LGTGNDLARA LGWGGGYTDE PIGKILREIG 490 500 510 520 530 540 MSQCVLMDRW RVKVTPNDDV TDDHVDRSKP NVPLNVINNY FSFGVDAHIA LEFHEAREAH 550 560 570 580 590 600 PERFNSRLRN KMYYGQMGGK DLILRQYRNL SQWVTLECDG QDFTGKLRDA GCHAVLFLNI 610 620 630 640 650 660 PSYGGGTHPW NDSFGASKPS IDDGLMEVVG LTTYQLPMLQ AGMHGTCICQ CRKARIITKR 670 680 690 700 710 720 TIPMQVDGEA CRVKPSVIEI ELLNKALMLS KRKHGRGDVQ VNPLEKMQLH ILRVTMQQYE 730 740 750 760 770 780 QYHYDKEMLR KLANKLGQIE IESQCDLEHV RNMLNTKFEE SISYPKVSQD WCFIDSCTAE 790 800 810 820 830 840 HYFRIDRAQE HLHYICDIAI DELYILDHEA ATMPQTPDQE RSFAAFSQRQ AQNERRQMDQ 850 860 870 880 890 900 AQGRGPGSTD EDLQIGSKPI KVMKWKSNKD RLFSFNEDVF GCGFSPILEQ TSDAILLAAQ 910 920 930 940 950 960 SGDLNMLRAL HEQGYSLQSV NKNGQTALHF ACKYNHRDIV KYIIASATRR LINMADKELG 970 980 990 1000 1010 1020 QTALHIAAEQ NRRDICVMLV AAGAHLDTLD SGGNTPMMVA FNKNANEIAT YLESQERFMH LEKQTRI
	Isoform C. Checksum: D8119DAF5644BDC4	FASTA	1,024	113,748
	10 20 30 40 50 60 MERLLHAVRE EFQTEDEYET EVDDEGNVLH RSSISSCSSS SSSSNTSSSS DGSNSTASQP 70 80 90 100 110 120 LSPSLPQPRR RLQRSDSFGS VGGGVAGGVA GSGATGAGGV RRFRRSSIGM QRKSAFRQRK 130 140 150 160 170 180 LDSLGAWRRK RRTASASNSR RPIRIVPDWT ENAVQGEHYW KPTSASGDLC CLNEECIKSG 190 200 210 220 230 240 QRMKCSACQL VAHHNCIPFV NEKSTLACKP TYRDVGIRQY REQTTTHHHW VHRKLEKGKC 250 260 270 280 290 300 KQCGKFFPMK QAVQSKLFGS KEIVALACAW CHEIYHNKEA CFNQAKIGEE CRLGNYAPII 310 320 330 340 350 360 VPPSWIVKLP TKGNFKSSIR VSNKNNAASG SGGGGAGGGA GGGGGKSKKQ TQRRQKGKEE 370 380 390 400 410 420 KKEPRAFIVK PIPSPEVIPV IVFINPKSGG NQGHKLLGKF QHLLNPRQVF DLTQGGPKMG 430 440 450 460 470 480 LDMFRKAPNL RVLACGGDGT VGWVLSVLDQ IQPPLQPAPA VGVLPLGTGN DLARALGWGG 490 500 510 520 530 540 GYTDEPIGKI LREIGMSQCV LMDRWRVKVT PNDDVTDDHV DRSKPNVPLN VINNYFSFGV 550 560 570 580 590 600 DAHIALEFHE AREAHPERFN SRLRNKMYYG QMGGKDLILR QYRNLSQWVT LECDGQDFTG 610 620 630 640 650 660 KLRDAGCHAV LFLNIPSYGG GTHPWNDSFG ASKPSIDDGL MEVVGLTTYQ LPMLQAGMHG 670 680 690 700 710 720 TCICQCRKAR IITKRTIPMQ VDGEACRVKP SVIEIELLNK ALMLSKRKHG RGDVQVNPLE 730 740 750 760 770 780 KMQLHILRVT MQQYEQYHYD KEMLRKLANK LGQIEIESQC DLEHVRNMLN TKFEESISYP 790 800 810 820 830 840 KVSQDWCFID SCTAEHYFRI DRAQEHLHYI CDIAIDELYI LDHEAATMPQ TPDQERSFAA 850 860 870 880 890 900 FSQRQAQNER RQMDQAQGRG PGSTDEDLQI GSKPIKVMKW KSPILEQTSD AILLAAQSGD 910 920 930 940 950 960 LNMLRALHEQ GYSLQSVNKN GQTALHFACK YNHRDIVKYI IASATRRLIN MADKELGQTA 970 980 990 1000 1010 1020 LHIAAEQNRR DICVMLVAAG AHLDTLDSGG NTPMMVAFNK NANEIATYLE SKQGTQPVDG WLDD

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Drosophila retinal degeneration A gene encodes an eye-specific diacylglycerol kinase with cysteine-rich zinc-finger motifs and ankyrin repeats." Masai I., Okazaki A., Hosoya T., Hotta Y. Proc. Natl. Acad. Sci. U.S.A. 90:11157-11161(1993) [PubMed: 8248222] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A), FUNCTION, TISSUE SPECIFICITY, DISRUPTION PHENOTYPE. Strain: Canton-S. Tissue: Head.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: GENOME REANNOTATION, ALTERNATIVE SPLICING.
[4]	"A Drosophila full-length cDNA resource." Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A., Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M., Celniker S.E. Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002) [PubMed: 12537569] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM A). Strain: Berkeley. Tissue: Head.
[5]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J.W., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R.A., Gonzalez M., Guarin H., Kronmiller B., Li P.W., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J.M., Paragas V., Park S., Patel S., Phouanenavong S., Wan K.H., Yu C., Lewis S.E., Rubin G.M., Celniker S.E. Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM B). Strain: Berkeley. Tissue: Head.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D17315 mRNA. Translation: BAA04135.1. AE014298 Genomic DNA. Translation: AAF46430.2. AE014298 Genomic DNA. Translation: ABW09364.1. AE014298 Genomic DNA. Translation: ABW09365.1. AY075349 mRNA. Translation: AAL68208.1. BT009959 mRNA. Translation: AAQ22428.1. Sequence problems.
PIR	T13709.
RefSeq	NP_001096916.1. NP_001096917.1. NP_511092.2.
UniGene	Dm.5516
3D structure databases
SMR	Q09103. Positions 812-1141, 1318-1446.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q09103. 1 interaction.
STRING	Q09103.
Genome annotation databases
Ensembl	FBtr0112550; FBpp0111462; FBgn0085373; Drosophila melanogaster. [Genome view] FBtr0112551; FBpp0111463; FBgn0085373; Drosophila melanogaster. [Genome view] FBtr0112552; FBpp0111464; FBgn0085373; Drosophila melanogaster. [Genome view]
GeneID	31826.
KEGG	dme:Dmel_CG34344.
NMPDR	fig|7227.3.peg.17065.
Organism-specific databases
CTD	31826.
FlyBase	FBgn0085373. rdgA.
Phylogenomic databases
eggNOG	inNOG05289.
InParanoid	Q09103.
OMA	GGPKMGL.
OrthoDB	EOG94XJP7.
PhylomeDB	Q09103.
Enzyme and pathway databases
BRENDA	2.7.1.107. 48.
Gene expression databases
GermOnline	CG10966. Drosophila melanogaster.
Family and domain databases
InterPro	IPR002110. Ankyrin_rpt. IPR020683. Ankyrin_rpt-contain_dom. IPR000756. Diacylglycerol_kin_accessory. IPR001206. Diacylglycerol_kinase_cat_dom. IPR002219. Prot_Kinase_C-like_PE/DAG_bd. [Graphical view]
Gene3D	G3DSA:1.25.40.20. ANK. 1 hit.
Pfam	PF00023. Ank. 2 hits. PF00130. C1_1. 2 hits. PF00609. DAGK_acc. 1 hit. PF00781. DAGK_cat. 1 hit. [Graphical view]
SMART	SM00248. ANK. 4 hits. SM00109. C1. 1 hit. SM00045. DAGKa. 1 hit. SM00046. DAGKc. 1 hit. [Graphical view]
PROSITE	PS50297. ANK_REP_REGION. 1 hit. PS50088. ANK_REPEAT. 2 hits. PS50146. DAGK. 1 hit. PS00479. ZF_DAG_PE_1. False negative. PS50081. ZF_DAG_PE_2. False negative. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	775516.

Entry information

Entry name

DGK2_DROME

Accession

Primary (citable) accession number: Q09103
Secondary accession number(s): A8JV38 , A8JV40, Q0KHU7, Q7YU71, Q8SY47, Q9W3A4

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	June 21, 2005
Last modified:	January 19, 2010
This is version 92 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Drosophila annotation project