Reviewed, UniProtKB/Swiss-Prot Q09053 (DHM2_METSP)

Names and origin

Protein names

Recommended name:
    Methanol dehydrogenase subunit 2
    EC=1.1.99.8
Alternative name(s):
    MDH small subunit beta

Gene names

Name:

moxI

Organism

Methylomonas sp.

Taxonomic identifier

418 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Methylococcales › Methylococcaceae › Methylomonas

Protein attributes

Sequence length	18 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	A primary alcohol + acceptor = an aldehyde + reduced acceptor. UniProtKB P29898
Subunit structure	Heterotetramer composed of 2 alpha and 2 beta subunits. Ref.1
Subcellular location	Periplasm By similarity. UniProtKB P29898
Sequence similarities	Belongs to the methanol dehydrogenase subunit 2 family.

Ontologies

Keywords
Biological process	Methanol utilization
Cellular component	Periplasm
Molecular function	Oxidoreductase
PTM	Disulfide bond
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	methanol oxidation Inferred from electronic annotation. Source: InterPro oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	periplasmic space Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	alcohol dehydrogenase (acceptor) activity Inferred from electronic annotation. Source: EC alcohol dehydrogenase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›18	›18	Methanol dehydrogenase subunit 2		PRO_0000205343
Amino acid modifications
	Disulfide bond	6 ↔ 11		By similarity UniProtKB P14775
Experimental info
	Non-terminal residue	18	1

Sequences

	Sequence		Length	Mass (Da)
	Q09053-1 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 2B0412DBD2B8B52D	FASTA	18	2,014
	10 YDGTNCKPGV CWEPKPGY

References

[1]	"Methanol oxidation genes in the marine methanotroph Methylomonas sp. strain A4." Waechter-Brulla D., DiSpirito A.A., Chistoserdova L.V., Lidstrom M.E. J. Bacteriol. 175:3767-3775(1993) [PubMed: 7685335] [Abstract] Cited for: PROTEIN SEQUENCE, SUBUNIT. Strain: A4.

Cross-references

3D structure databases
HSSP	HSSP built from PDB template 1LRW based on UniProtKB P29898.
ModBase	Search...
Family and domain databases
InterPro	IPR003420. Meth_DH_bsu. [Graphical view]
Pfam	PF02315. MDH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DHM2_METSP

Accession

Primary (citable) accession number: Q09053

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 10, 2006
Last sequence update:	February 1, 1997
Last modified:	June 16, 2009
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)