Reviewed, UniProtKB/Swiss-Prot Q09053 (DHM2_METSP)

Names and origin

Protein names

Recommended name:
    Methanol dehydrogenase subunit 2
    EC=1.1.99.8
Alternative name(s):
    MDH small subunit beta

Gene names

Name:

moxI

Organism

Methylomonas sp.

Taxonomic identifier

418 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Methylococcales › Methylococcaceae › Methylomonas

Protein attributes

Sequence length	18 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	A primary alcohol + acceptor = an aldehyde + reduced acceptor.
Subunit structure	Heterotetramer composed of 2 alpha and 2 beta subunits.
Subcellular location	PeriplasmBy similarity.
Sequence similarities	Belongs to the methanol dehydrogenase subunit 2 family.

Ontologies

Keywords
Biological process	Methanol utilization
Cellular component	Periplasm
Molecular function	Oxidoreductase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	methanol oxidation Inferred from electronic annotation. Source: InterPro oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	periplasmic space Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	alcohol dehydrogenase (acceptor) activity Inferred from electronic annotation. Source: EC alcohol dehydrogenase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›18	›18	Methanol dehydrogenase subunit 2		PRO_0000205343
Amino acid modifications
	Disulfide bond	6 ↔ 11		By similarity
Experimental info
	Non-terminal residue	18	1

Sequences

	Sequence		Length	Mass (Da)
	Q09053-1 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 2B0412DBD2B8B52D	FASTA	18	2,014
	10 YDGTNCKPGV CWEPKPGY

References

[1]	"Methanol oxidation genes in the marine methanotroph Methylomonas sp. strain A4." Waechter-Brulla D., DiSpirito A.A., Chistoserdova L.V., Lidstrom M.E. J. Bacteriol. 175:3767-3775(1993) [PubMed: 7685335] [Abstract] Cited for: PROTEIN SEQUENCE, SUBUNIT. Strain: A4.

Cross-references

3D structure databases
HSSP	HSSP built from PDB template 1LRW based on UniProtKB P29898.
ModBase	Search...
Family and domain databases
InterPro	IPR003420. Meth_DHase_bsu. [Graphical view]
Pfam	PF02315. MDH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DHM2_METSP

Accession

Primary (citable) accession number: Q09053

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 10, 2006
Last sequence update:	February 1, 1997
Last modified:	November 25, 2008
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)