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Protein

Xylose isomerase

Gene

xylA

Organism
Stigmatella aurantiaca (strain DW4/3-1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei102 – 1021UniRule annotation
Active sitei105 – 1051UniRule annotation
Metal bindingi233 – 2331Magnesium 1UniRule annotation
Metal bindingi269 – 2691Magnesium 1UniRule annotation
Metal bindingi269 – 2691Magnesium 2UniRule annotation
Metal bindingi272 – 2721Magnesium 2UniRule annotation
Metal bindingi297 – 2971Magnesium 1UniRule annotation
Metal bindingi308 – 3081Magnesium 2UniRule annotation
Metal bindingi310 – 3101Magnesium 2UniRule annotation
Metal bindingi340 – 3401Magnesium 1UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotation, Xylose metabolismUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciSAUR378806:GCZI-2372-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotationImported
Ordered Locus Names:STAUR_2372Imported
ORF Names:STIAU_1199Imported
OrganismiStigmatella aurantiaca (strain DW4/3-1)Imported
Taxonomic identifieri378806 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeCystobacteraceaeStigmatella
ProteomesiUP000001351 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PRIDEiQ08YE2.

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi378806.STAUR_2372.

Structurei

3D structure databases

ProteinModelPortaliQ08YE2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

KOiK01805.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q08YE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MREPFFADIA PVRYEGLKST HPLAYRWYEP NRLVLGRSMA EHLRLAVCYW
60 70 80 90 100
HTFCWAGSDP FGPATMPRPW MQPGDAMALA EQKLSVAFEL FEKLGVPFFT
110 120 130 140 150
FHDRDLAPEL GSLRASQHAL KVMLDKAQVM MERTGVKLLW GTANLFSHPR
160 170 180 190 200
YMAGAATNPD PEVFAHAAAQ VRDALEATHR LGGANYVLWG GREGYDTLLN
210 220 230 240 250
THLKREIDQL GRFLNLVVEH KHKLGFKGTI LIEPKPMEPT KHQYDYDVST
260 270 280 290 300
VYGFLERSGL AKEVKVNIEV NHATLAGHTF DHEVATAIAL GIFGSIDMNR
310 320 330 340 350
GDPQNGWDTD QFPNNAPELV LPLYRILQAG GFTTGGINFD AKVRRQSIEP
360 370 380 390 400
VDLLHAHVGA IDVLARALLA AAAMLEEGAL SRHIDQRYAG WEGELGRKIT
410 420 430
EGQIDLAGLA NLAVDADLAP KPRSGRQEML ENLVNRYI
Length:438
Mass (Da):48,793
Last modified:October 31, 2006 - v1
Checksum:iD79D3CE090618302
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002271 Genomic DNA. Translation: ADO70176.1.
AAMD01000080 Genomic DNA. Translation: EAU65496.1.
RefSeqiWP_002615196.1. NZ_AAMD01000080.1.
YP_003952003.1. NC_014623.1.

Genome annotation databases

EnsemblBacteriaiADO70176; ADO70176; STAUR_2372.
EAU65496; EAU65496; STIAU_1199.
KEGGisur:STAUR_2372.
PATRICi38557084. VBIStiAur43712_4612.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002271 Genomic DNA. Translation: ADO70176.1.
AAMD01000080 Genomic DNA. Translation: EAU65496.1.
RefSeqiWP_002615196.1. NZ_AAMD01000080.1.
YP_003952003.1. NC_014623.1.

3D structure databases

ProteinModelPortaliQ08YE2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi378806.STAUR_2372.

Proteomic databases

PRIDEiQ08YE2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADO70176; ADO70176; STAUR_2372.
EAU65496; EAU65496; STIAU_1199.
KEGGisur:STAUR_2372.
PATRICi38557084. VBIStiAur43712_4612.

Phylogenomic databases

KOiK01805.

Enzyme and pathway databases

BioCyciSAUR378806:GCZI-2372-MONOMER.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Nierman W.C.
    Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DW4/3-1Imported.
  2. "Evolution of fruiting body formation in Myxococcales: a comparative genomic analysis."
    Huntley S., Hamann N., Wegener-Feldbruegge S., Treuner-Lange A., Kube M., Reinhardt R., Klages S., Mueller R., Ronning C.M., Nierman W.C., Sogaard-Andersen L.
    Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DW4/3-1Imported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DW4/3-1Imported.

Entry informationi

Entry nameiQ08YE2_STIAD
AccessioniPrimary (citable) accession number: Q08YE2
Entry historyi
Integrated into UniProtKB/TrEMBL: October 31, 2006
Last sequence update: October 31, 2006
Last modified: June 24, 2015
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.