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Q08FW1

- PAP1_DPV83

UniProt

Q08FW1 - PAP1_DPV83

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Protein
Poly(A) polymerase catalytic subunit
Gene
PAPL, DpV83gp040
Organism
Deerpox virus (strain Mule deer/United States/W-848-83/1983) (DPV)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Polymerase that creates the 3'-poly(A) tail of mRNA's.

Catalytic activityi

ATP + RNA(n) = diphosphate + RNA(n+1).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei192 – 1921 By similarity
Active sitei194 – 1941 By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. polynucleotide adenylyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. mRNA processing Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

mRNA processing, Transcription

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Poly(A) polymerase catalytic subunit (EC:2.7.7.19)
Alternative name(s):
Poly(A) polymerase large subunit
Short name:
PAP-L
Gene namesi
Name:PAPL
Ordered Locus Names:DpV83gp040
OrganismiDeerpox virus (strain Mule deer/United States/W-848-83/1983) (DPV)
Taxonomic identifieri305674 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeCervidpoxvirusunclassified Cervidpoxvirus
Virus hostiOdocoileus hemionus (Mule deer) (Black-tailed deer) [TaxID: 9872]
ProteomesiUP000000866: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 470470Poly(A) polymerase catalytic subunit
PRO_0000308931Add
BLAST

Interactioni

Subunit structurei

Heterodimer of a large (catalytic) subunit and a small (regulatory) subunit By similarity.

Structurei

3D structure databases

ProteinModelPortaliQ08FW1.
SMRiQ08FW1. Positions 7-468.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiIPR024231. Pox_polyA_pol_nucTrfase.
IPR004976. Poxvirus_polyA_pol_cat.
IPR024397. Poxvirus_polyA_pol_cat_C.
IPR024398. Poxvirus_polyA_pol_cat_N.
[Graphical view]
PfamiPF03296. Pox_polyA_pol. 1 hit.
PF12629. Pox_polyA_pol_C. 1 hit.
PF12630. Pox_polyA_pol_N. 1 hit.
[Graphical view]
PIRSFiPIRSF015693. VAC-48L_nuct. 1 hit.

Sequencei

Sequence statusi: Complete.

Q08FW1-1 [UniParc]FASTAAdd to Basket

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MNRHISEILE KYLGRIPSLT EYHTLKSQYK NIHRVNIFNK DIFISLIKKN    50
KKKFFSDIDT SVSEIKKLVF DYFTKQEQTY SIGKLYTIIE LQTILVTTYT 100
DILGVLTTKG PDIFSSNVQY NTSSMQKIAN DALNSMNIAT ISDKVMGRHN 150
VSSLVCNVNS LMEEYLRRHN KSCICYGSYS LHLLNPEIKY GDIDILQTNS 200
RTFLIDLAFL IKFITGYNVI LLKVPYLKNY MVLKDQNDSH IIDSFNIRQE 250
TMQHIPKILI DNIYIVDPTI QLLSMLKMLS QIDRLEDLAK NPDKLTIRFA 300
TLLEYVRNKY GIILNGNSNN MPMPSTIDIK KRIITVDTKY YNFAYDKCYV 350
YLDENSLSSD ILSLNADDAV DFENVSNSAF LVNDKTLYTY FSNTILLSGN 400
DKIHEISSRG ISAHILIYQA LMKYDISIPL TDIVNSLIGR NKQPIYEIIP 450
RDKKTGKHGI IDIEKDIITH 470
Length:470
Mass (Da):54,186
Last modified:October 31, 2006 - v1
Checksum:iD290C021F12E25C2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY689436 Genomic DNA. Translation: ABI99196.1.
RefSeqiYP_227416.1. NC_006966.1.

Genome annotation databases

GeneIDi3346388.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY689436 Genomic DNA. Translation: ABI99196.1 .
RefSeqi YP_227416.1. NC_006966.1.

3D structure databases

ProteinModelPortali Q08FW1.
SMRi Q08FW1. Positions 7-468.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3346388.

Family and domain databases

InterProi IPR024231. Pox_polyA_pol_nucTrfase.
IPR004976. Poxvirus_polyA_pol_cat.
IPR024397. Poxvirus_polyA_pol_cat_C.
IPR024398. Poxvirus_polyA_pol_cat_N.
[Graphical view ]
Pfami PF03296. Pox_polyA_pol. 1 hit.
PF12629. Pox_polyA_pol_C. 1 hit.
PF12630. Pox_polyA_pol_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF015693. VAC-48L_nuct. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiPAP1_DPV83
AccessioniPrimary (citable) accession number: Q08FW1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: October 31, 2006
Last modified: May 14, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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