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Q08FW1

- PAP1_DPV83

UniProt

Q08FW1 - PAP1_DPV83

Protein

Poly(A) polymerase catalytic subunit

Gene

PAPL

Organism
Deerpox virus (strain Mule deer/United States/W-848-83/1983) (DPV)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 31 (01 Oct 2014)
      Sequence version 1 (31 Oct 2006)
      Previous versions | rss
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    Functioni

    Polymerase that creates the 3'-poly(A) tail of mRNA's.

    Catalytic activityi

    ATP + RNA(n) = diphosphate + RNA(n+1).

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei192 – 1921By similarity
    Active sitei194 – 1941By similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. polynucleotide adenylyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. mRNA processing Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    mRNA processing, Transcription

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Poly(A) polymerase catalytic subunit (EC:2.7.7.19)
    Alternative name(s):
    Poly(A) polymerase large subunit
    Short name:
    PAP-L
    Gene namesi
    Name:PAPL
    Ordered Locus Names:DpV83gp040
    OrganismiDeerpox virus (strain Mule deer/United States/W-848-83/1983) (DPV)
    Taxonomic identifieri305674 [NCBI]
    Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeCervidpoxvirusunclassified Cervidpoxvirus
    Virus hostiOdocoileus hemionus (Mule deer) (Black-tailed deer) [TaxID: 9872]
    ProteomesiUP000000866: Genome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 470470Poly(A) polymerase catalytic subunitPRO_0000308931Add
    BLAST

    Interactioni

    Subunit structurei

    Heterodimer of a large (catalytic) subunit and a small (regulatory) subunit.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ08FW1.
    SMRiQ08FW1. Positions 7-468.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    InterProiIPR024231. Pox_polyA_pol_nucTrfase.
    IPR004976. Poxvirus_polyA_pol_cat.
    IPR024397. Poxvirus_polyA_pol_cat_C.
    IPR024398. Poxvirus_polyA_pol_cat_N.
    [Graphical view]
    PfamiPF03296. Pox_polyA_pol. 1 hit.
    PF12629. Pox_polyA_pol_C. 1 hit.
    PF12630. Pox_polyA_pol_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF015693. VAC-48L_nuct. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q08FW1-1 [UniParc]FASTAAdd to Basket

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    MNRHISEILE KYLGRIPSLT EYHTLKSQYK NIHRVNIFNK DIFISLIKKN    50
    KKKFFSDIDT SVSEIKKLVF DYFTKQEQTY SIGKLYTIIE LQTILVTTYT 100
    DILGVLTTKG PDIFSSNVQY NTSSMQKIAN DALNSMNIAT ISDKVMGRHN 150
    VSSLVCNVNS LMEEYLRRHN KSCICYGSYS LHLLNPEIKY GDIDILQTNS 200
    RTFLIDLAFL IKFITGYNVI LLKVPYLKNY MVLKDQNDSH IIDSFNIRQE 250
    TMQHIPKILI DNIYIVDPTI QLLSMLKMLS QIDRLEDLAK NPDKLTIRFA 300
    TLLEYVRNKY GIILNGNSNN MPMPSTIDIK KRIITVDTKY YNFAYDKCYV 350
    YLDENSLSSD ILSLNADDAV DFENVSNSAF LVNDKTLYTY FSNTILLSGN 400
    DKIHEISSRG ISAHILIYQA LMKYDISIPL TDIVNSLIGR NKQPIYEIIP 450
    RDKKTGKHGI IDIEKDIITH 470
    Length:470
    Mass (Da):54,186
    Last modified:October 31, 2006 - v1
    Checksum:iD290C021F12E25C2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY689436 Genomic DNA. Translation: ABI99196.1.
    RefSeqiYP_227416.1. NC_006966.1.

    Genome annotation databases

    GeneIDi3346388.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY689436 Genomic DNA. Translation: ABI99196.1 .
    RefSeqi YP_227416.1. NC_006966.1.

    3D structure databases

    ProteinModelPortali Q08FW1.
    SMRi Q08FW1. Positions 7-468.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3346388.

    Family and domain databases

    InterProi IPR024231. Pox_polyA_pol_nucTrfase.
    IPR004976. Poxvirus_polyA_pol_cat.
    IPR024397. Poxvirus_polyA_pol_cat_C.
    IPR024398. Poxvirus_polyA_pol_cat_N.
    [Graphical view ]
    Pfami PF03296. Pox_polyA_pol. 1 hit.
    PF12629. Pox_polyA_pol_C. 1 hit.
    PF12630. Pox_polyA_pol_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF015693. VAC-48L_nuct. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiPAP1_DPV83
    AccessioniPrimary (citable) accession number: Q08FW1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 23, 2007
    Last sequence update: October 31, 2006
    Last modified: October 1, 2014
    This is version 31 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3