Reviewed, UniProtKB/Swiss-Prot Q08FW1 (PAP1_DPV83)

Names and origin

Protein names

Recommended name:
    Poly(A) polymerase catalytic subunit
    EC=2.7.7.19
Alternative name(s):
    Poly(A) polymerase large subunit
      Short name=PAP-L

Gene names

Name:	PAPL
Ordered Locus Names:	DpV83gp040

Organism

Deerpox virus (strain W-848-83) (DPV)

Taxonomic identifier

305674 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Poxviridae › Chordopoxvirinae › Cervidpoxvirus

Virus host

Odocoileus hemionus (Mule deer) (Black-tailed deer) [TaxID: 9872]

Protein attributes

Sequence length	470 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Polymerase that creates the 3'-poly(A) tail of mRNA's.
Catalytic activity	ATP + RNA(n) = diphosphate + RNA(n+1).
Subunit structure	Heterodimer of a large (catalytic) subunit and a small (regulatory) subunit By similarity.
Sequence similarities	Belongs to the poxviridae poly(A) polymerase catalytic subunit family.

Ontologies

Keywords
Biological process	Transcription mRNA processing
Ligand	ATP-binding Nucleotide-binding
Molecular function	Transferase
Gene Ontology (GO)
Biological process	mRNA processing Inferred from electronic annotation. Source: UniProtKB-KW transcription Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW polynucleotide adenylyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 470	470	Poly(A) polymerase catalytic subunit		PRO_0000308931
Sites
	Active site	192	1	By similarity
	Active site	194	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q08FW1-1 [UniParc]. Last modified October 31, 2006. Version 1. Checksum: D290C021F12E25C2	FASTA	470	54,186
	10 20 30 40 50 60 MNRHISEILE KYLGRIPSLT EYHTLKSQYK NIHRVNIFNK DIFISLIKKN KKKFFSDIDT 70 80 90 100 110 120 SVSEIKKLVF DYFTKQEQTY SIGKLYTIIE LQTILVTTYT DILGVLTTKG PDIFSSNVQY 130 140 150 160 170 180 NTSSMQKIAN DALNSMNIAT ISDKVMGRHN VSSLVCNVNS LMEEYLRRHN KSCICYGSYS 190 200 210 220 230 240 LHLLNPEIKY GDIDILQTNS RTFLIDLAFL IKFITGYNVI LLKVPYLKNY MVLKDQNDSH 250 260 270 280 290 300 IIDSFNIRQE TMQHIPKILI DNIYIVDPTI QLLSMLKMLS QIDRLEDLAK NPDKLTIRFA 310 320 330 340 350 360 TLLEYVRNKY GIILNGNSNN MPMPSTIDIK KRIITVDTKY YNFAYDKCYV YLDENSLSSD 370 380 390 400 410 420 ILSLNADDAV DFENVSNSAF LVNDKTLYTY FSNTILLSGN DKIHEISSRG ISAHILIYQA 430 440 450 460 470 LMKYDISIPL TDIVNSLIGR NKQPIYEIIP RDKKTGKHGI IDIEKDIITH

References

[1]	"Genome of deerpox virus." Afonso C.L., Delhon G., Tulman E.R., Lu Z., Zsak A., Becerra V.M., Zsak L., Kutish G.F., Rock D.L. J. Virol. 79:966-977(2005) [PubMed: 15613325] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AY689436 Genomic DNA. Translation: ABI99196.1.
RefSeq	YP_227416.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3346388.
Family and domain databases
InterPro	IPR004976. PolyA_pol_cat_poxviral. [Graphical view]
Pfam	PF03296. Pox_polyA_pol. 1 hit. [Graphical view]
PIRSF	PIRSF015693. VAC-48L_nuct. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PAP1_DPV83

Accession

Primary (citable) accession number: Q08FW1

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 23, 2007
Last sequence update:	October 31, 2006
Last modified:	June 16, 2009
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Virus (Virus annotation project)