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Q08FE1 (PAP1_DPV84) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Poly(A) polymerase catalytic subunit

EC=2.7.7.19
Alternative name(s):
Poly(A) polymerase large subunit
Short name=PAP-L
Gene names
Name:PAPL
Ordered Locus Names:DpV84gp040
OrganismDeerpox virus (strain W-1170-84) (DPV)
Taxonomic identifier305676 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeCervidpoxvirusunclassified Cervidpoxvirus
Virus hostOdocoileus hemionus (Mule deer) (Black-tailed deer) [TaxID: 9872]

Protein attributes

Sequence length470 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Polymerase that creates the 3'-poly(A) tail of mRNA's.

Catalytic activity

ATP + RNA(n) = diphosphate + RNA(n+1).

Subunit structure

Heterodimer of a large (catalytic) subunit and a small (regulatory) subunit By similarity.

Sequence similarities

Belongs to the poxviridae poly(A) polymerase catalytic subunit family.

Ontologies

Keywords
   Biological processmRNA processing
Transcription
   LigandATP-binding
Nucleotide-binding
   Molecular functionTransferase
Gene Ontology (GO)
   Biological_processmRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

polynucleotide adenylyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 470470Poly(A) polymerase catalytic subunit
PRO_0000308930

Sites

Active site1921 By similarity
Active site1941 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q08FE1 [UniParc].

Last modified October 31, 2006. Version 1.
Checksum: 2AA5851274C44B4A

FASTA47054,089
        10         20         30         40         50         60 
MNRHISEILE KYLGRIPSLT EYHTLKSQYK NIHRVNIFNK DIFISLIKKN KKKFFSDIDT 

        70         80         90        100        110        120 
SVSEIKKLVF DYFTKQEQTY SIGKLYTIIE LQTILVTTYT DILGVLTTKG PDIFSSNVQY 

       130        140        150        160        170        180 
NTSSMQKIAS DALNSMNIAT ISDKVMGRHN VSSLVCNVNS LMEEYLRRHN KSCICYGSYS 

       190        200        210        220        230        240 
LHLLNPEIKY GDIDILQTNS RTFLIDLAFL IKFITGYNVI LLKVPYLKNY MVLKDQNDSH 

       250        260        270        280        290        300 
IIDSFNIRQE TMQHIPKVLI DNIYIVDPTI QLLSMLKMLS QIDRLEDLAK NPDKLTIRFA 

       310        320        330        340        350        360 
TLLEYVRNKY GIILNGNSNN MPMPATIDIK KRIITVDTKY YNFAYDKCYV YLDENSLSSD 

       370        380        390        400        410        420 
ILSLNADDAV DFENVSNSAF LVNDKTLYTY FSNTVLLSGN DKIHEISSRG ISAHILIYQA 

       430        440        450        460        470 
LMKHDISIPL TDIVNSLIGR NKQPIYEIIP RDKKTGKHGI IDIEKDIITH 

« Hide

References

[1]"Genome of deerpox virus."
Afonso C.L., Delhon G., Tulman E.R., Lu Z., Zsak A., Becerra V.M., Zsak L., Kutish G.F., Rock D.L.
J. Virol. 79:966-977(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY689437 Genomic DNA. Translation: ABI99025.1.
RefSeqYP_002302381.1. NC_006967.1.

3D structure databases

ProteinModelPortalQ08FE1.
SMRQ08FE1. Positions 7-468.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7011871.

Family and domain databases

InterProIPR024231. Pox_polyA_pol_nucTrfase.
IPR004976. Poxvirus_polyA_pol_cat.
IPR024397. Poxvirus_polyA_pol_cat_C.
IPR024398. Poxvirus_polyA_pol_cat_N.
[Graphical view]
PfamPF03296. Pox_polyA_pol. 1 hit.
PF12629. Pox_polyA_pol_C. 1 hit.
PF12630. Pox_polyA_pol_N. 1 hit.
[Graphical view]
PIRSFPIRSF015693. VAC-48L_nuct. 1 hit.
ProtoNetSearch...

Entry information

Entry namePAP1_DPV84
AccessionPrimary (citable) accession number: Q08FE1
Entry history
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: October 31, 2006
Last modified: May 14, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families