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Protein
Submitted name:

Retinoblastoma 1

Gene

RB1

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Retinoblastoma 1Imported
Gene namesi
Name:RB1Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ08E68
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini103 – 229DUF3452InterPro annotationAdd BLAST127
Domaini373 – 573RB_AInterPro annotationAdd BLAST201
Domaini660 – 761CYCLINInterPro annotationAdd BLAST102
Domaini768 – 927Rb_CInterPro annotationAdd BLAST160

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili314 – 334Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1010 Eukaryota
ENOG410XQF7 LUCA
HOGENOMiHOG000136539
HOVERGENiHBG008967
KOiK06618

Family and domain databases

CDDicd00043 CYCLIN, 1 hit
InterProiView protein in InterPro
IPR013763 Cyclin-like
IPR036915 Cyclin-like_sf
IPR033057 RB1
IPR002720 RB_A
IPR002719 RB_B
IPR015030 RB_C
IPR028309 RB_fam
IPR024599 RB_N
PANTHERiPTHR13742 PTHR13742, 1 hit
PTHR13742:SF17 PTHR13742:SF17, 1 hit
PfamiView protein in Pfam
PF11934 DUF3452, 1 hit
PF01858 RB_A, 1 hit
PF01857 RB_B, 1 hit
PF08934 Rb_C, 1 hit
SMARTiView protein in SMART
SM00385 CYCLIN, 1 hit
SM01367 DUF3452, 1 hit
SM01368 RB_A, 1 hit
SM01369 Rb_C, 1 hit
SUPFAMiSSF47954 SSF47954, 2 hits

Sequencei

Sequence statusi: Complete.

Q08E68-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPKTPRRAA AAAAAAAAEP PPPPLPPPPE EDPEQDSGSE DLPLARLEFE
60 70 80 90 100
ETEEPDFTAL CQKLKLPDHV RERAWLTWEK VSSVDGVLEG YVQKKKELWG
110 120 130 140 150
ICIFIAAVDL DEMPFTFTEL QKNIETSVYK FFDLLKEIDT STKVDNAMSR
160 170 180 190 200
LLKKYNVLCA LYSKLERTCE LIYLTQPSSS ISTEINSMLV LKVSWITFLL
210 220 230 240 250
AKGQVLQMED DLVISFQLML CVLDYFIKLS PPALLKDPYK TAVIPINGSP
260 270 280 290 300
RTPRRGQNRS ARIAKQLEND TRIIEVLCKE HECNIDEVKN VYFKNFIPFM
310 320 330 340 350
NSLGIVASNG LPEVENLSKQ YEEIYLKNKD LDARLFLDHD KTLQADPTDS
360 370 380 390 400
FEMQRTPRKS NPDEEVNMIL PQTPVRTVMN TIQQLMMILN SASDQPSENL
410 420 430 440 450
ISYFNNCTVN PKDSILKRVK DIGDVFKEKF AKAVGQGCME IGSQRYKLGV
460 470 480 490 500
RLYYRVMESM LKSEEERLSI QNFSKLLNDN IFHMSLLACA LEVVMATYSR
510 520 530 540 550
SMSQSLDTGT DLSFPWILNV FNLKAFDFYK VIESFIKAEA NLTREMIKHL
560 570 580 590 600
ERCEHRIMES LAWLSDSPLF DLIKQAKDRE GPVDHFEPAC TLNLPLQNNH
610 620 630 640 650
TAADMYLSPV RSPKKKGPTP RVNSTPNSEA QATSAFQTQK PLKSTSLSLF
660 670 680 690 700
YKKVYRLAYL RLNTLCARFL SDHPELEHII WTLFQHTLQN EYELMRDRHL
710 720 730 740 750
DQIMMCSMYG ICKVKNIDLK FKIIVTAYKD LPHAVQETFK RVLIREEEYD
760 770 780 790 800
SIIVFYNSVF MQRLKTNILQ YASTRPPTLS PIPHIPRSPY KFSSSPLRIP
810 820 830 840 850
GGNIYISPLN NPYKISEGLP TPTKMTPRSR ILVSIGESFG TSEKFQKINQ
860 870 880 890 900
MVCNSDRVLK RSAEGSNPPK PLKKLRFDIE GSDEADGSKH LPGESKFQQK
910 920
LAEMTSTRTR MQKQKMNESV DTSNREEK
Length:928
Mass (Da):106,205
Last modified:October 31, 2006 - v1
Checksum:i2D85C4633E26705A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC123388 mRNA Translation: AAI23389.1
RefSeqiNP_001070375.1, NM_001076907.1
UniGeneiBt.47780

Genome annotation databases

GeneIDi534712
KEGGibta:534712

Similar proteinsi

Entry informationi

Entry nameiQ08E68_BOVIN
AccessioniPrimary (citable) accession number: Q08E68
Entry historyiIntegrated into UniProtKB/TrEMBL: October 31, 2006
Last sequence update: October 31, 2006
Last modified: May 23, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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