ID   PGM1_BOVIN              Reviewed;         562 AA.
AC   Q08DP0;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2006, sequence version 1.
DT   16-JUN-2009, entry version 21.
DE   RecName: Full=Phosphoglucomutase-1;
DE            Short=PGM 1;
DE            EC=5.4.2.2;
DE   AltName: Full=Glucose phosphomutase 1;
GN   Name=PGM1;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
OC   Pecora; Bovidae; Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal muscle;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: This enzyme participates in both the breakdown and
CC       synthesis of glucose (By similarity).
CC   -!- CATALYTIC ACTIVITY: Alpha-D-glucose 1-phosphate = alpha-D-glucose
CC       6-phosphate.
CC   -!- COFACTOR: Binds 1 magnesium ion per subunit (By similarity).
CC   -!- SUBUNIT: Monomer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the phosphohexose mutase family.
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DR   EMBL; BC123640; AAI23641.1; -; mRNA.
DR   IPI; IPI00701643; -.
DR   RefSeq; NP_001070371.1; -.
DR   UniGene; Bt.59999; -.
DR   SMR; Q08DP0; 2-562.
DR   Ensembl; ENSBTAG00000019011; Bos taurus.
DR   GeneID; 534402; -.
DR   KEGG; bta:534402; -.
DR   HOVERGEN; Q08DP0; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004614; F:phosphoglucomutase activity; ISS:AgBase.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR005844; A-D-PHexomutase_a/b/a-I.
DR   InterPro; IPR016055; A-D-PHexomutase_a/b/a-I/II/III.
DR   InterPro; IPR005845; A-D-PHexomutase_a/b/a-II.
DR   InterPro; IPR005846; A-D-PHexomutase_a/b/a-III.
DR   InterPro; IPR005843; A-D-PHexomutase_C.
DR   InterPro; IPR016066; A-D-PHexomutase_CS.
DR   InterPro; IPR005841; A-D-PHexomutase_N.
DR   Gene3D; G3DSA:3.40.120.10; A-D-PHexomutase_a/b/a-I/II/III; 3.
DR   Pfam; PF02878; PGM_PMM_I; 1.
DR   Pfam; PF02879; PGM_PMM_II; 1.
DR   Pfam; PF02880; PGM_PMM_III; 1.
DR   Pfam; PF00408; PGM_PMM_IV; 1.
DR   PRINTS; PR00509; PGMPMM.
DR   PROSITE; PS00710; PGM_PMM; 1.
PE   2: Evidence at transcript level;
KW   Carbohydrate metabolism; Cytoplasm; Glucose metabolism; Isomerase;
KW   Magnesium; Metal-binding; Phosphoprotein.
FT   INIT_MET      1      1       Removed (By similarity).
FT   CHAIN         2    562       Phosphoglucomutase-1.
FT                                /FTId=PRO_0000343708.
FT   ACT_SITE    117    117       Phosphoserine intermediate (By
FT                                similarity).
FT   METAL       117    117       Magnesium; via phosphate group (By
FT                                similarity).
FT   METAL       288    288       Magnesium (By similarity).
FT   METAL       290    290       Magnesium (By similarity).
FT   METAL       292    292       Magnesium (By similarity).
FT   MOD_RES     115    115       Phosphothreonine (By similarity).
FT   MOD_RES     117    117       Phosphoserine (By similarity).
FT   MOD_RES     353    353       Phosphotyrosine (By similarity).
SQ   SEQUENCE   562 AA;  61589 MW;  D843620DD3815E8A CRC64;
     MVKIVTVKTK AYQDQKPGTS GLRKRVKVFQ SSSNYAENFI QSIISTVEPA QRQEATLVVG
     GDGRFYMKEA IQLIVRIAAA NGIGRLVIGQ NGILSTPAVS CIIRKIKAIG GIILTASHNP
     GGPNGDFGIK FNISNGGPAP EAITDKIFQI SKTIEEYAIC PDLHVDLGVL GKQQFDLENK
     FKPFTVEIVD SVEAYATMLR NIFDFNALKE LLSGPNRLKI RIDAMHGVVG PYVKKILCEE
     LGAPANSAVN CVPLEDFGGH HPDPNLTYAA DLVETMKTGE HDFGAAFDGD GDRNMILGKH
     GFFVNPSDSV AVIAANIFSI PYFQQTGVRG FARSMPTSGA LDRVANATKI ALYETPTGWK
     FFGNLMDASK LSLCGEESFG TGSDHIREKD GLWAVLAWLS ILATRKQSVE DILKDHWQKY
     GRNFFTRYDY EEVEAEGANK MMKELEALIS DRSFVGKQFP VGDKVYTVEK IDNFEYSDPV
     DGSISRNQGL RLLFADGSRI IFRLSGTGSA GATIRLYIDS YEKDLAKIYQ DPQVMLAPLI
     SIALKVSQLQ EKTGRTAPTV IT
//