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Protein
Submitted name:

Tumor necrosis factor receptor superfamily, member 21

Gene

TNFRSF21

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Tumor necrosis factor receptor superfamily, member 21Imported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:TNFRSF21Imported
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 23

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei347 – 36721HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000026719.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini87 – 12842TNFR-CysInterPro annotationAdd
BLAST
Domaini412 – 49584DeathInterPro annotationAdd
BLAST

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IHQ6. Eukaryota.
ENOG410YYKW. LUCA.
GeneTreeiENSGT00760000119204.
HOGENOMiHOG000136852.
HOVERGENiHBG054218.
KOiK05157.
OMAiFSRPEHM.
OrthoDBiEOG786H2Q.
TreeFamiTF331157.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
InterProiIPR011029. DEATH-like_dom.
IPR000488. Death_domain.
IPR001368. TNFR/NGFR_Cys_rich_reg.
IPR022330. TNFR_21.
IPR011641. Tyr-kin_ephrin_A/B_rcpt-like.
[Graphical view]
PfamiPF00531. Death. 1 hit.
PF00020. TNFR_c6. 1 hit.
[Graphical view]
PRINTSiPR01971. TNFACTORR21.
SMARTiSM00005. DEATH. 1 hit.
SM01411. Ephrin_rec_like. 2 hits.
SM00208. TNFR. 4 hits.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS50017. DEATH_DOMAIN. 1 hit.
PS50050. TNFR_NGFR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q08DN1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGTFTSSSTA LASCSRMAGA TMIAGSFLLL GFLSTTRAQP EQKAPSLIGK
60 70 80 90 100
YHHVDRITGQ VLTCDKCPAG TYVSEHCTNI SLRVCSSCPT GTFTRHENGI
110 120 130 140 150
EKCHECSQRC PWPMIEKLPC TALTDRECTC PPGMFQSNGT CAPHTVCPVG
160 170 180 190 200
WGVRKKGTEM EDVRCKQCAR GTFSDVPSSV MRCRAYTDCL SQNMVVIKLG
210 220 230 240 250
TKEADNVCGP LPSSSSTAPP SPGTTSLSRP EHTEPHDVPS STLIPKGINS
260 270 280 290 300
TESNSSASVR PKVPSGTQEG TAPDNTSSAS GEEGVNKTFP KLQVANHQQG
310 320 330 340 350
PHHRHILKLL PSMEATGGEK SSTPIKGLKR GHPRQNPHKH FDINEHLPWM
360 370 380 390 400
IVLFLLLVLV VIVVCSIRKS SRTLKKGPRQ DPSAIVEKAG LKKSMAPTQN
410 420 430 440 450
REKWIYYCNG HGIDILKLVA AQVGSQWKDI YQFLCNASER EVAAFSNGYT
460 470 480 490 500
ADHERAYAAL QHWTIRGPEA SLAQLISALR QHRRNDVVEK IRGLMEDTAQ
510 520 530 540 550
LDTDKLALPM SPSPLGPSPI PSPNTKLENS TLLTVEPSPL DKNKGFFVDE
560 570 580 590 600
SEPLLRCDST SSGSSALSRN GSFITKEKKD TVLRQVRLDP CDLQPIFDDM
610 620 630 640 650
LHILNPEELR VIEETPQAED KLDRLFEIIG VKSQEASQTL LDSVYSHLPD

LL
Length:652
Mass (Da):71,305
Last modified:October 31, 2006 - v1
Checksum:i94D513EFFF04DD19
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02055176 Genomic DNA. No translation available.
DAAA02055177 Genomic DNA. No translation available.
DAAA02055178 Genomic DNA. No translation available.
DAAA02055179 Genomic DNA. No translation available.
BC123657 mRNA. Translation: AAI23658.1.
RefSeqiNP_001070379.1. NM_001076911.1.
UniGeneiBt.45971.

Genome annotation databases

EnsembliENSBTAT00000026719; ENSBTAP00000026719; ENSBTAG00000020054.
GeneIDi537922.
KEGGibta:537922.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02055176 Genomic DNA. No translation available.
DAAA02055177 Genomic DNA. No translation available.
DAAA02055178 Genomic DNA. No translation available.
DAAA02055179 Genomic DNA. No translation available.
BC123657 mRNA. Translation: AAI23658.1.
RefSeqiNP_001070379.1. NM_001076911.1.
UniGeneiBt.45971.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000026719.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000026719; ENSBTAP00000026719; ENSBTAG00000020054.
GeneIDi537922.
KEGGibta:537922.

Organism-specific databases

CTDi27242.

Phylogenomic databases

eggNOGiENOG410IHQ6. Eukaryota.
ENOG410YYKW. LUCA.
GeneTreeiENSGT00760000119204.
HOGENOMiHOG000136852.
HOVERGENiHBG054218.
KOiK05157.
OMAiFSRPEHM.
OrthoDBiEOG786H2Q.
TreeFamiTF331157.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
InterProiIPR011029. DEATH-like_dom.
IPR000488. Death_domain.
IPR001368. TNFR/NGFR_Cys_rich_reg.
IPR022330. TNFR_21.
IPR011641. Tyr-kin_ephrin_A/B_rcpt-like.
[Graphical view]
PfamiPF00531. Death. 1 hit.
PF00020. TNFR_c6. 1 hit.
[Graphical view]
PRINTSiPR01971. TNFACTORR21.
SMARTiSM00005. DEATH. 1 hit.
SM01411. Ephrin_rec_like. 2 hits.
SM00208. TNFR. 4 hits.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS50017. DEATH_DOMAIN. 1 hit.
PS50050. TNFR_NGFR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: L1 HerefordImported.
    Tissue: Cerebral cortexImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HerefordImported.
  3. Ensembl
    Submitted (MAR-2016) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: HerefordImported.

Entry informationi

Entry nameiQ08DN1_BOVIN
AccessioniPrimary (citable) accession number: Q08DN1
Secondary accession number(s): F1N407
Entry historyi
Integrated into UniProtKB/TrEMBL: October 31, 2006
Last sequence update: October 31, 2006
Last modified: July 6, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.