Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cytochrome c oxidase assembly protein COX15 homolog

Gene

COX15

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May be involved in the biosynthesis of heme A.

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-BTA-189451 Heme biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase assembly protein COX15 homolog
Gene namesi
Name:COX15
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 26

Organism-specific databases

VGNCiVGNC:27629 COX15

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei71 – 91HelicalSequence analysisAdd BLAST21
Transmembranei157 – 174HelicalSequence analysisAdd BLAST18
Transmembranei187 – 207HelicalSequence analysisAdd BLAST21
Transmembranei230 – 250HelicalSequence analysisAdd BLAST21
Transmembranei272 – 292HelicalSequence analysisAdd BLAST21
Transmembranei327 – 347HelicalSequence analysisAdd BLAST21
Transmembranei360 – 380HelicalSequence analysisAdd BLAST21
Transmembranei385 – 405HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002744861 – 413Cytochrome c oxidase assembly protein COX15 homologAdd BLAST413

Proteomic databases

PaxDbiQ08DG6
PRIDEiQ08DG6

Expressioni

Gene expression databases

BgeeiENSBTAG00000045703

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000055003

Family & Domainsi

Sequence similaritiesi

Belongs to the COX15/CtaA family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG2725 Eukaryota
COG1612 LUCA
GeneTreeiENSGT00390000002223
HOVERGENiHBG051086
InParanoidiQ08DG6
KOiK02259
OMAiAGLIYNT
OrthoDBiEOG091G08NN
TreeFamiTF105073

Family and domain databases

HAMAPiMF_01665 HemeA_synth_type2, 1 hit
InterProiView protein in InterPro
IPR003780 COX15/CtaA_fam
IPR023754 HemeA_Synthase_type2
IPR009003 Peptidase_S1_PA
PANTHERiPTHR23289 PTHR23289, 1 hit
PfamiView protein in Pfam
PF02628 COX15-CtaA, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit

Sequencei

Sequence statusi: Complete.

Q08DG6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQRLLFTPLT AFLGSPCLRL LVPRVAPRTQ CGCSCGIRRP LRPGQYSTIS
60 70 80 90 100
DVALQPGRST VSLPSKAAER VVGRWLLVCS GTVAGAVILG GVTRLTESGL
110 120 130 140 150
SMVDWHLIKE MKPPTSKEEW EAEFQKYQQF PEFKILNHDM TLAEFKFIWY
160 170 180 190 200
MEYSHRMWGR LVGLAYILPA AYFWKKGWLT RGLKGRVLAL CGLVCFQGLL
210 220 230 240 250
GWYMVKSGLE EKPDSHDIPR VSQYRLAAHL GSALVLYCAS LWTSLSLLLP
260 270 280 290 300
QHKLTETRQL LRLRRFAHGT AGLVFLTALS GAFVAGLDAG LVYNSFPKMG
310 320 330 340 350
ESWIPEDLFT FSPLLRNVFE NPTMVQFDHR VLGIASVTAV TVLYFLSRRI
360 370 380 390 400
PLPRRTKIAA TTLLALAYTQ VGLGISTLLM YVPTPLAATH QSGSLALLSV
410
ALWLMNELRR VPK
Length:413
Mass (Da):46,126
Last modified:October 31, 2006 - v1
Checksum:iA5E1CB2F19BF559B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC123760 mRNA Translation: AAI23761.1
RefSeqiNP_001070329.1, NM_001076861.1
UniGeneiBt.26951

Genome annotation databases

EnsembliENSBTAT00000064176; ENSBTAP00000055003; ENSBTAG00000045703
GeneIDi517811
KEGGibta:517811

Similar proteinsi

Entry informationi

Entry nameiCOX15_BOVIN
AccessioniPrimary (citable) accession number: Q08DG6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: October 31, 2006
Last modified: March 28, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health