Q08C57 (ADXL_DANRE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Adrenodoxin-like protein, mitochondrial

Alternative name(s):
Ferredoxin-1-like protein

Gene names

Name:	fdx1l
ORF Names:	zgc:153554

Organism

Danio rerio (Zebrafish) (Brachydanio rerio)

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	195 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Cofactor	Binds 1 2Fe-2S cluster By similarity.
Subcellular location	Mitochondrion matrix By similarity.
Sequence similarities	Belongs to the adrenodoxin/putidaredoxin family. Contains 1 2Fe-2S ferredoxin-type domain.

Ontologies

Keywords
Biological process	Electron transport Transport
Cellular component	Mitochondrion
Domain	Transit peptide
Ligand	2Fe-2S Iron Iron-sulfur Metal-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	mitochondrial matrix Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	2 iron, 2 sulfur cluster binding Inferred from electronic annotation. Source: UniProtKB-KW electron carrier activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – 61	61	Mitochondrion Potential
	Chain	62 – 195	134	Adrenodoxin-like protein, mitochondrial		PRO_0000325954
Regions
	Domain	81 – 182	102	2Fe-2S ferredoxin-type
Sites
	Metal binding	117	1	Iron-sulfur (2Fe-2S) By similarity
	Metal binding	123	1	Iron-sulfur (2Fe-2S) By similarity
	Metal binding	126	1	Iron-sulfur (2Fe-2S) By similarity
	Metal binding	163	1	Iron-sulfur (2Fe-2S) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q08C57 [UniParc]. Last modified October 31, 2006. Version 1. Checksum: B4EE7717920597D6	FASTA	195	21,468
	10 20 30 40 50 60 MAAAAAVRAG VNFTQRLNRI SPVCRVCPLL RLNRCTGAAV RRAVDGFSAP SRRLRTSIGV 70 80 90 100 110 120 CQSEDSSAPE EDAHAQEHIV NVVYIDRSGR RIPVQARVGD NVLYLAHKHG IDLEGACEAS 130 140 150 160 170 180 LACSTCHVYV SSGHYDRLPE PEEREDDMLD MAPLLQENSR LGCQIILTPE LDGMELTLPK 190 VTRNFYVDGH VPKPH

References

[1]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Eye.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC124384 mRNA. Translation: AAI24385.1.
IPI	IPI00801804.
RefSeq	NP_001070132.1. NM_001076664.1.
UniGene	Dr.84490.
3D structure databases
ProteinModelPortal	Q08C57.
ModBase	Search...
Protein-protein interaction databases
STRING	Q08C57.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	767726.
KEGG	dre:767726.
Organism-specific databases
CTD	112812.
ZFIN	ZDB-GENE-060929-1046. zgc:153554.
Phylogenomic databases
eggNOG	fiNOG14186.
GeneTree	ENSGT00530000063577.
HOGENOM	HBG524254.
HOVERGEN	HBG055801.
OMA	PADEEND.
OrthoDB	EOG4MKNHB.
PhylomeDB	Q08C57.
Gene expression databases
ArrayExpress	Q08C57.
Bgee	Q08C57.
Family and domain databases
InterPro	IPR001055. Adrenodoxin. IPR018298. Adrenodoxin_Fe-S_BS. IPR012675. Beta-grasp_ferredoxin-type. IPR001041. Ferredoxin. [Graphical view]
Gene3D	G3DSA:3.10.20.30. Ferredoxin_fold. 1 hit.
Pfam	PF00111. Fer2. 1 hit. [Graphical view]
PRINTS	PR00355. ADRENODOXIN.
SUPFAM	SSF54292. Ferredoxin. 1 hit.
PROSITE	PS51085. 2FE2S_FER_2. 1 hit. PS00814. ADX. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ADXL_DANRE

Accession

Primary (citable) accession number: Q08C57

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	October 31, 2006
Last modified:	September 21, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program