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Protein

ATP synthase subunit alpha

Gene

atp5a1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Produces ATP from ADP in the presence of a proton gradient across the membrane.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

ATP synthesis, Hydrogen ion transportUniRule annotation, Ion transport, Transport

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DRE-163210. Formation of ATP by chemiosmotic coupling.

Names & Taxonomyi

Protein namesi
Recommended name:
ATP synthase subunit alphaUniRule annotation
Gene namesi
Name:atp5a1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 21

Organism-specific databases

ZFINiZDB-GENE-060201-1. atp5a1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CF(1)UniRule annotation

Expressioni

Gene expression databases

BgeeiENSDARG00000010149.

Interactioni

Protein-protein interaction databases

MINTiMINT-8283638.
STRINGi7955.ENSDARP00000027947.

Structurei

3D structure databases

SMRiQ08BA1. Positions 66-543.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini68 – 13467ATP-synt_ab_NInterPro annotationAdd
BLAST
Domaini191 – 414224ATP-synt_abInterPro annotationAdd
BLAST
Domaini421 – 545125ATP-synt_ab_CInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ATPase alpha/beta chains family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1353. Eukaryota.
COG0056. LUCA.
GeneTreeiENSGT00550000074846.
HOGENOMiHOG000130111.
HOVERGENiHBG001536.
KOiK02132.
OMAiMVQDIRR.
OrthoDBiEOG091G0D1M.
PhylomeDBiQ08BA1.
TreeFamiTF300321.

Family and domain databases

CDDicd01132. F1_ATPase_alpha. 1 hit.
Gene3Di2.40.30.20. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_01346. ATP_synth_alpha_bact. 1 hit.
InterProiIPR020003. ATPase_a/bsu_AS.
IPR023366. ATPase_asu-like.
IPR005294. ATPase_F1-cplx_asu.
IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
IPR004100. ATPase_F1_a/bsu_N.
IPR033732. F1_ATPase_alpha.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR15184:SF3. PTHR15184:SF3. 1 hit.
PfamiPF00006. ATP-synt_ab. 1 hit.
PF00306. ATP-synt_ab_C. 1 hit.
PF02874. ATP-synt_ab_N. 1 hit.
[Graphical view]
PIRSFiPIRSF039088. F_ATPase_subunit_alpha. 1 hit.
SUPFAMiSSF47917. SSF47917. 1 hit.
SSF50615. SSF50615. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00962. atpA. 1 hit.
PROSITEiPS00152. ATPASE_ALPHA_BETA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q08BA1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSVRVAAAL ARTLPRRAGF VSKNVAAACV GAKNLHTARP WLQKTGTAEV
60 70 80 90 100
SSILEEKILG ADTGAELEET GRVLSIGDGI ARVYGLRNVQ AEEMVEFSSG
110 120 130 140 150
LKGMSLNLEP DNVGVVVFGN DKLIKEGDIV KRTGAIVDVP VGEELLGRVV
160 170 180 190 200
DALGNPIDGK GPLGSKERRR VGLKAPGIIP RISVREPMQT GIKAVDSLVP
210 220 230 240 250
IGRGQRELII GDRQTGKTAI AIDTIINQKR FNEGTEEKKK LYCIYVAIGQ
260 270 280 290 300
KRSTVAQLVK RLTDADAMKY TIVVSATASD AAPLQYLAPY SGCSMGEYFR
310 320 330 340 350
DNGKHALIIY DDLSKQAVAY RQMSLLLRRP PGREAYPGDV FYLHSRLLER
360 370 380 390 400
AAKMNDNFGG GSLTALPVIE TQAGDVSAYI PTNVISITDG QIFLETELFY
410 420 430 440 450
KGIRPAINVG LSVSRVGSAA QTRAMKQVAG TMKLELAQYR EVAAFAQFGS
460 470 480 490 500
DLDAATQQLL NRGVRLTELL KQGQYSPMAI EEQVAVIYAG VRGHLDKMEP
510 520 530 540 550
SKITKFEKAF LQHVISQHQD LLAAIRSDGK ISEASDAKLK EIVLNFLSSF

E
Length:551
Mass (Da):59,744
Last modified:October 31, 2006 - v1
Checksum:i62F4F3C493E231BC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU466288 Genomic DNA. No translation available.
BC124811 mRNA. Translation: AAI24812.1.
RefSeqiNP_001070823.1. NM_001077355.1.
UniGeneiDr.76050.

Genome annotation databases

EnsembliENSDART00000024199; ENSDARP00000027947; ENSDARG00000010149.
GeneIDi553755.
KEGGidre:553755.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU466288 Genomic DNA. No translation available.
BC124811 mRNA. Translation: AAI24812.1.
RefSeqiNP_001070823.1. NM_001077355.1.
UniGeneiDr.76050.

3D structure databases

SMRiQ08BA1. Positions 66-543.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-8283638.
STRINGi7955.ENSDARP00000027947.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000024199; ENSDARP00000027947; ENSDARG00000010149.
GeneIDi553755.
KEGGidre:553755.

Organism-specific databases

CTDi498.
ZFINiZDB-GENE-060201-1. atp5a1.

Phylogenomic databases

eggNOGiKOG1353. Eukaryota.
COG0056. LUCA.
GeneTreeiENSGT00550000074846.
HOGENOMiHOG000130111.
HOVERGENiHBG001536.
KOiK02132.
OMAiMVQDIRR.
OrthoDBiEOG091G0D1M.
PhylomeDBiQ08BA1.
TreeFamiTF300321.

Enzyme and pathway databases

ReactomeiR-DRE-163210. Formation of ATP by chemiosmotic coupling.

Gene expression databases

BgeeiENSDARG00000010149.

Family and domain databases

CDDicd01132. F1_ATPase_alpha. 1 hit.
Gene3Di2.40.30.20. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_01346. ATP_synth_alpha_bact. 1 hit.
InterProiIPR020003. ATPase_a/bsu_AS.
IPR023366. ATPase_asu-like.
IPR005294. ATPase_F1-cplx_asu.
IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
IPR004100. ATPase_F1_a/bsu_N.
IPR033732. F1_ATPase_alpha.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR15184:SF3. PTHR15184:SF3. 1 hit.
PfamiPF00006. ATP-synt_ab. 1 hit.
PF00306. ATP-synt_ab_C. 1 hit.
PF02874. ATP-synt_ab_N. 1 hit.
[Graphical view]
PIRSFiPIRSF039088. F_ATPase_subunit_alpha. 1 hit.
SUPFAMiSSF47917. SSF47917. 1 hit.
SSF50615. SSF50615. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00962. atpA. 1 hit.
PROSITEiPS00152. ATPASE_ALPHA_BETA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ08BA1_DANRE
AccessioniPrimary (citable) accession number: Q08BA1
Entry historyi
Integrated into UniProtKB/TrEMBL: October 31, 2006
Last sequence update: October 31, 2006
Last modified: September 7, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.