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Protein

ATP synthase subunit alpha

Gene

atp5fa1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Produces ATP from ADP in the presence of a proton gradient across the membrane.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processATP synthesis, Hydrogen ion transportUniRule annotation, Ion transport, Transport
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DRE-163210 Formation of ATP by chemiosmotic coupling
R-DRE-8949613 Cristae formation

Names & Taxonomyi

Protein namesi
Recommended name:
ATP synthase subunit alphaUniRule annotation
Gene namesi
Name:atp5fa1Imported
Synonyms:atp5a1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 21

Organism-specific databases

ZFINiZDB-GENE-060201-1 atp5fa1

Subcellular locationi

Keywords - Cellular componenti

CF(1)UniRule annotation

Expressioni

Gene expression databases

BgeeiENSDARG00000010149

Interactioni

Protein-protein interaction databases

IntActiQ08BA1, 1 interactor
STRINGi7955.ENSDARP00000027947

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini68 – 134ATP-synt_ab_NInterPro annotationAdd BLAST67
Domaini191 – 414ATP-synt_abInterPro annotationAdd BLAST224
Domaini421 – 545ATP-synt_ab_CInterPro annotationAdd BLAST125

Sequence similaritiesi

Belongs to the ATPase alpha/beta chains family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1353 Eukaryota
COG0056 LUCA
GeneTreeiENSGT00550000074846
HOGENOMiHOG000130111
HOVERGENiHBG001536
KOiK02132
OMAiQDKCDSS
OrthoDBiEOG091G0D1M
TreeFamiTF300321

Family and domain databases

CDDicd01132 F1_ATPase_alpha, 1 hit
Gene3Di1.20.150.20, 1 hit
2.40.30.20, 1 hit
HAMAPiMF_01346 ATP_synth_alpha_bact, 1 hit
InterProiView protein in InterPro
IPR023366 ATP_synth_asu-like_sf
IPR000793 ATP_synth_asu_C
IPR038376 ATP_synth_asu_C_sf
IPR033732 ATP_synth_F1_a
IPR005294 ATP_synth_F1_asu
IPR020003 ATPase_a/bsu_AS
IPR004100 ATPase_F1/V1/A1_a/bsu_N
IPR036121 ATPase_F1/V1/A1_a/bsu_N_sf
IPR000194 ATPase_F1/V1/A1_a/bsu_nucl-bd
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00006 ATP-synt_ab, 1 hit
PF00306 ATP-synt_ab_C, 1 hit
PF02874 ATP-synt_ab_N, 1 hit
PIRSFiPIRSF039088 F_ATPase_subunit_alpha, 1 hit
SUPFAMiSSF50615 SSF50615, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00962 atpA, 1 hit
PROSITEiView protein in PROSITE
PS00152 ATPASE_ALPHA_BETA, 1 hit

Sequencei

Sequence statusi: Complete.

Q08BA1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSVRVAAAL ARTLPRRAGF VSKNVAAACV GAKNLHTARP WLQKTGTAEV
60 70 80 90 100
SSILEEKILG ADTGAELEET GRVLSIGDGI ARVYGLRNVQ AEEMVEFSSG
110 120 130 140 150
LKGMSLNLEP DNVGVVVFGN DKLIKEGDIV KRTGAIVDVP VGEELLGRVV
160 170 180 190 200
DALGNPIDGK GPLGSKERRR VGLKAPGIIP RISVREPMQT GIKAVDSLVP
210 220 230 240 250
IGRGQRELII GDRQTGKTAI AIDTIINQKR FNEGTEEKKK LYCIYVAIGQ
260 270 280 290 300
KRSTVAQLVK RLTDADAMKY TIVVSATASD AAPLQYLAPY SGCSMGEYFR
310 320 330 340 350
DNGKHALIIY DDLSKQAVAY RQMSLLLRRP PGREAYPGDV FYLHSRLLER
360 370 380 390 400
AAKMNDNFGG GSLTALPVIE TQAGDVSAYI PTNVISITDG QIFLETELFY
410 420 430 440 450
KGIRPAINVG LSVSRVGSAA QTRAMKQVAG TMKLELAQYR EVAAFAQFGS
460 470 480 490 500
DLDAATQQLL NRGVRLTELL KQGQYSPMAI EEQVAVIYAG VRGHLDKMEP
510 520 530 540 550
SKITKFEKAF LQHVISQHQD LLAAIRSDGK ISEASDAKLK EIVLNFLSSF

E
Length:551
Mass (Da):59,744
Last modified:October 31, 2006 - v1
Checksum:i62F4F3C493E231BC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU466288 Genomic DNA No translation available.
BC124811 mRNA Translation: AAI24812.1
RefSeqiNP_001070823.1, NM_001077355.1
UniGeneiDr.76050

Genome annotation databases

EnsembliENSDART00000024199; ENSDARP00000027947; ENSDARG00000010149
GeneIDi553755
KEGGidre:553755

Similar proteinsi

Entry informationi

Entry nameiQ08BA1_DANRE
AccessioniPrimary (citable) accession number: Q08BA1
Entry historyiIntegrated into UniProtKB/TrEMBL: October 31, 2006
Last sequence update: October 31, 2006
Last modified: March 28, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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