ADAM33 protein - Homo sapiens (Human)

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Unreviewed, UniProtKB/TrEMBL Q08AM2 (Q08AM2_HUMAN)

Last modified November 25, 2008. Version 19. History...

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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information

Names and origin

Protein names

Submitted name:
ADAM33 protein EMBL AAI25114.1

Gene names

Name:

ADAM33 EMBL AAI25114.1

Organism

Homo sapiens (Human) EMBL AAI25114.1

Taxonomic identifier

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	692 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 EGF-like domain. Spearmint SPM001590

Contains 1 disintegrin domain. RuleBase RU004074V3 Spearmint SPM001590

Contains 1 peptidase M12B domain. RuleBase RU004141V0 Spearmint SPM001590

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Spearmint SPM001590
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

Q08AM2-1 [UniParc].

Last modified October 31, 2006. Version 1.
Checksum: D1204B0CC0EFD8FD
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692

75,270

        10         20         30         40         50         60 
MGWRPRRARG TPLLLLLLLL LLWPVPGAGV LQGHIPGQPV TPHWVLDGQP WRTVSLEEPV 

        70         80         90        100        110        120 
SKPDMGLVAL EAEGQELLLE LEKNHRLLAP GYIETHYGPD GQPVVLAPNH TDHCHYQGRV 

       130        140        150        160        170        180 
RGFPDSWVVL CTCSGMSGLI TLSRNASYYL RPWPPRGSKD FSTHEIFRME QLLTWKGTCG 

       190        200        210        220        230        240 
HRDPGNKAGM TSLPGGPQSR GRREARRTRK YLELYIVADH TLFLTRHRNL NHTKQRLLEV 

       250        260        270        280        290        300 
ANYVDQLLRT LDIQVALTGL EVWTERDRSR RQLRAFFRKG GGACLSNAPD PGLPVPPALC 

       310        320        330        340        350        360 
GNGFVEAGEE CDCGPGQECR DLCCFAHNCS LRPGAQCAHG DCCVRCLLKP AGALCRQAMG 

       370        380        390        400        410        420 
DCDLPEFCTG TSSHCPPDVY LLDGSPCARG SGYCWDGACP TLEQQCQQLW GPGSHPAPEA 

       430        440        450        460        470        480 
CFQVVNSAGD AHGNCGQDSE GHFLPCAGRD ALCGKLQCQG GKPSLLAPHM VPVDSTVHLD 

       490        500        510        520        530        540 
GQEVTCRGAL ALPSAQLDLL GLGLVEPGTQ CGPRMVCQSR RCRKNAFQEL QRCLTACHSH 

       550        560        570        580        590        600 
GVCNSNHNCH CAPGWAPPFC DKPGFGGSMD SGPVQAENHD TFLLAMLLSV LLPLLPGAGL 

       610        620        630        640        650        660 
AWCCYRLPGA HLQRCSWGCR RDPACSGPKD GPHRDHPLGG VHPMELGPTA TGQPWPLDPE 

       670        680        690 
NSHEPSSHPE KPLPAVSPDP QDQVQMPRSC LW

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: PCR rescued clones EMBL AAI25114.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
	BC125113 mRNA. Translation: AAI25114.1.
UniGene	Hs.173716
3D structure databases
SMR	Q08AM2. Positions 204-270.
ModBase	Search...
Organism-specific databases
HGNC	HGNC:15478. ADAM33.
GenAtlas	Search...
GeneCards	Search...
Phylogenomic databases
HOVERGEN	Q08AM2.
Family and domain databases
InterPro	IPR006586. ADAM_Cys-rich. IPR001762. Blood-coag_inhib_Disintegrin. IPR006210. EGF. IPR000742. EGF_3. IPR013111. EGF_extracell. IPR013032. EGF_like_reg_CS. IPR001590. Peptidase_M12B. IPR002870. Peptidase_M12B_N. [Graphical view]
Gene3D	G3DSA:4.10.70.10. Blood-coag_inhib_Disintegrin. 1 hit.
Pfam	PF08516. ADAM_CR. 1 hit. PF00200. Disintegrin. 1 hit. PF07974. EGF_2. 1 hit. PF01562. Pep_M12B_propep. 1 hit. PF01421. Reprolysin. 1 hit. [Graphical view]
PRINTS	PR00289. DISINTEGRIN.
ProDom	PD000664. Disintegrin. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00608. ACR. 1 hit. SM00050. DISIN. 1 hit. SM00181. EGF. 1 hit. [Graphical view]
PROSITE	PS50215. ADAM_MEPRO. 1 hit. PS00427. DISINTEGRIN_1. 1 hit. PS50214. DISINTEGRIN_2. 1 hit. PS01186. EGF_2. 1 hit. PS50026. EGF_3. 1 hit. [Graphical view]

Entry information

Entry name

Q08AM2_HUMAN

Accession

Primary (citable) accession number: Q08AM2

Entry history

Integrated into UniProtKB/TrEMBL:	October 31, 2006
Last sequence update:	October 31, 2006
Last modified:	November 25, 2008
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information