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Q08A45 (SYGA_SHEFN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycine--tRNA ligase alpha subunit

EC=6.1.1.14
Alternative name(s):
Glycyl-tRNA synthetase alpha subunit
Short name=GlyRS
Gene names
Name:glyQ
Ordered Locus Names:Sfri_0007
OrganismShewanella frigidimarina (strain NCIMB 400) [Complete proteome] [HAMAP]
Taxonomic identifier318167 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Protein attributes

Sequence length301 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP-Rule MF_00254

Subunit structure

Tetramer of two alpha and two beta subunits By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00254.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

glycine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 301301Glycine--tRNA ligase alpha subunit HAMAP-Rule MF_00254
PRO_1000047486

Sequences

Sequence LengthMass (Da)Tools
Q08A45 [UniParc].

Last modified October 31, 2006. Version 1.
Checksum: 0F1F8544C4BFC294

FASTA30134,552
        10         20         30         40         50         60 
MTTKHDVKTF QGFILTLQEY WAQQGCAIVQ PLDMEVGAGT FHPQTFLRSL GPEPMSSAYV 

        70         80         90        100        110        120 
QPSRRPTDGR YGENPNRLQH YYQFQVVLKP SPDNIQELYL GSLEALGIDT KVHDIRFVED 

       130        140        150        160        170        180 
NWESPTLGAW GLGWEIWLNG MEVTQFTYFQ QVGGIECSPV TGEITYGLER LAMYIQEVDS 

       190        200        210        220        230        240 
VYDLVWTDGP LGRVTYGDIF HQNEVEQSTY NFEHADVDFM FTLFDQCEKM CMHLLSLEKP 

       250        260        270        280        290        300 
LPLPAYEQVM KASHAFNLLD ARHAISVTER QRYILRVRTM AKGVAESYYQ AREALGFPMC 


K 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000447 Genomic DNA. Translation: ABI69870.1.
RefSeqYP_748708.1. NC_008345.1.

3D structure databases

ProteinModelPortalQ08A45.
SMRQ08A45. Positions 10-292.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING318167.Sfri_0007.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABI69870; ABI69870; Sfri_0007.
GeneID4277690.
KEGGsfr:Sfri_0007.
PATRIC23493721. VBISheFri14343_0007.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0752.
HOGENOMHOG000264291.
KOK01878.
OMACVILQPY.
OrthoDBEOG661H9S.
ProtClustDBPRK09348.

Enzyme and pathway databases

BioCycSFRI318167:GIXS-7-MONOMER.

Family and domain databases

HAMAPMF_00254. Gly_tRNA_synth_alpha.
InterProIPR006194. Gly-tRNA-synth_heterodimer.
IPR002310. Gly-tRNA_ligase_asu.
[Graphical view]
PfamPF02091. tRNA-synt_2e. 1 hit.
[Graphical view]
PRINTSPR01044. TRNASYNTHGA.
TIGRFAMsTIGR00388. glyQ. 1 hit.
PROSITEPS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYGA_SHEFN
AccessionPrimary (citable) accession number: Q08A45
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 31, 2006
Last modified: February 19, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries