Reviewed, UniProtKB/Swiss-Prot Q08A04 (UBIC_SHEFN)

Names and origin

Protein names

Recommended name:
    Probable chorismate--pyruvate lyase
      Short name=CL
      Short name=CPL
    EC=4.1.3.40

Gene names

Name:	ubiC
Ordered Locus Names:	Sfri_0048

Organism

Shewanella frigidimarina (strain NCIMB 400) [Complete proteome] [HAMAP]

Taxonomic identifier

318167 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	204 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway By similarity.
Catalytic activity	Chorismate = 4-hydroxybenzoate + pyruvate. HAMAP MF_01632
Pathway	Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_01632
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the ubiC family.

Ontologies

Keywords
Biological process	Ubiquinone biosynthesis
Cellular component	Cytoplasm
Ligand	Pyruvate
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyruvate biosynthetic process Inferred from electronic annotation. Source: HAMAP ubiquinone biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	chorismate lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 204	204	Probable chorismate--pyruvate lyase HAMAP MF_01632		PRO_0000292078
Sites
	Binding site	78	1	Substrate By similarity
	Binding site	131	1	Substrate; via amide nitrogen By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q08A04-1 [UniParc]. Last modified October 31, 2006. Version 1. Checksum: 2B155DE25BBD5262	FASTA	204	23,100
	10 20 30 40 50 60 MNVTSISFPY GESIHWFSPQ KIDSLPHSQL KEWLLATGSL TQRLKTHCKH FEVKVLGEHL 70 80 90 100 110 120 LEPLADEFPA QTNPVWIREV LLCLDGTPWV FARTLIPQTI LGSQTPNYQN ADDKQIREQQ 130 140 150 160 170 180 NDFTRLGTRP LGELLFSSPD ITPGNIEVAQ FETCGRLAAL ATSLNQQVNS SLWGRRRYFN 190 200 LHGSQLIVSE IFLPAAVEYI NQSI

References

[1]

"Complete sequence of Shewanella frigidimarina NCIMB 400." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Fredrickson J.K., Kolker E., McCuel L.A., DiChristina T., Nealson K.H., Newman D., Tiedje J.M. , Zhou J., Romine M.F., Culley D.E., Serres M., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000447 Genomic DNA. Translation: ABI69911.1.
RefSeq	YP_748749.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4278255.
GenomeReviews	Gene locus Sfri_0048 in contig CP000447_GR.
KEGG	sfr:Sfri_0048.
NMPDR	fig|318167.10.peg.48.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q08A04.
OMA	Q08A04. WGRRSRF.
Family and domain databases
HAMAP	MF_01632. [Tree]
InterPro	IPR007440. Chorismate_lyase. [Graphical view]
Pfam	PF04345. Chor_lyase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UBIC_SHEFN

Accession

Primary (citable) accession number: Q08A04

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 26, 2007
Last sequence update:	October 31, 2006
Last modified:	June 16, 2009
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)