Q08A02 (RLMF_SHEFN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal RNA large subunit methyltransferase F
EC=2.1.1.181

Alternative name(s):
23S rRNA mA1618 methyltransferase
rRNA adenine N-6-methyltransferase

Gene names

Name:	rlmF
Ordered Locus Names:	Sfri_0050

Organism

Shewanella frigidimarina (strain NCIMB 400) [Complete proteome] [HAMAP]

Taxonomic identifier

318167 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	360 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Specifically methylates the adenine in position 1618 of 23S rRNA By similarity. HAMAP MF_01848
Catalytic activity	S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA. HAMAP MF_01848
Subcellular location	Cytoplasm Potential HAMAP MF_01848.
Sequence similarities	Belongs to the methyltransferase superfamily. METTL16/rlmF family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	rRNA (adenine-N6-)-methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 360	360	Ribosomal RNA large subunit methyltransferase F HAMAP MF_01848		PRO_0000349955

Sequences

	Sequence		Length	Mass (Da)
	Q08A02 [UniParc]. Last modified October 31, 2006. Version 1. Checksum: AE375BD772BD1BDA	FASTA	360	39,753
	10 20 30 40 50 60 MTRSTTPPMR AKHSSAKRSP SRSAAKVNPV SVKPNKPLLS KALHPRNAHL QGYDFATLII 70 80 90 100 110 120 AMPALAAFVR PNPYGNPSID FADPKAVKSL NAALLLSEYH INGWDIPEGY LCPPVPGRVD 130 140 150 160 170 180 YLHYIADLLA VKGKVVKGAS IRGLDIGTGA NGIYPLLGIQ TYGWQFVASD IDPVSIDNVA 190 200 210 220 230 240 KIAQQNEKIT AHLQLRLQPQ PEHIFKNIIA ADERFDVTLC NPPFHSSLAE ASEGSLRKVK 250 260 270 280 290 300 NLAKNQQQKH GQQSRKLAVS QAKPTLNFGG QKAELWCQGG EQQFLANMIK QSRDYANQVL 310 320 330 340 350 360 WFTSLVSKSD NLKPCYQLLK QLNAVEVKTI EMTQGNKATR ILAWSFLTPA IHQQWATLRP

References

[1]

"Complete sequence of Shewanella frigidimarina NCIMB 400." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Fredrickson J.K., Kolker E., McCuel L.A., DiChristina T., Nealson K.H., Newman D., Tiedje J.M. , Zhou J., Romine M.F., Culley D.E., Serres M., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCIMB 400.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000447 Genomic DNA. Translation: ABI69913.1.
RefSeq	YP_748751.1. NC_008345.1.
3D structure databases
ProteinModelPortal	Q08A02.
ModBase	Search...
Protein-protein interaction databases
STRING	Q08A02.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4278257.
GenomeReviews	Gene locus Sfri_0050 in contig CP000447_GR.
KEGG	sfr:Sfri_0050.
NMPDR	fig|318167.10.peg.51.
PATRIC	23493819. VBISheFri14343_0053.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3129.
HOGENOM	HBG747880.
OMA	DFANPEA.
PhylomeDB	Q08A02.
ProtClustDB	PRK11727.
Family and domain databases
HAMAP	MF_01848. 23SrRNA_methyltr_F. [Tree]
InterPro	IPR016909. rRNA_lsu_methyltransferase_F. IPR010286. SAM-Mtase_prd. [Graphical view]
KO	K06970.
PANTHER	PTHR13393. DUF890. 1 hit.
Pfam	PF05971. Methyltransf_10. 1 hit. [Graphical view]
PIRSF	PIRSF029038. Mtase_YbiN_prd. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RLMF_SHEFN

Accession

Primary (citable) accession number: Q08A02

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 2, 2008
Last sequence update:	October 31, 2006
Last modified:	January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program