Reviewed, UniProtKB/Swiss-Prot Q08968 (YP222_YEAST)

Names and origin

Protein names

Recommended name:
    UPF0061 protein YPL222W

Gene names

Ordered Locus Names:

YPL222W

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	688 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Miscellaneous	Present with 2430 molecules/cell in log phase SD medium.
Sequence similarities	Belongs to the UPF0061 (SELO) family.

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	mitochondrion Inferred from direct assay. Source: SGD
Molecular function	protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
	P43582	1	EBI-29375,EBI-22766
PRP40	P33203	1	EBI-29375,EBI-701
RSP5	P39940	1	EBI-29375,EBI-16219
SSM4	P40318	1	EBI-29375,EBI-18208

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 688	688	UPF0061 protein YPL222W		PRO_0000121401

Sequences

	Sequence		Length	Mass (Da)
	Q08968-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 7C56CD503ED24B1E	FASTA	688	78,313
	10 20 30 40 50 60 MGEKRTIIKA LKNSAASHFI KKLTADTSLS SIQEAINVVQ QYNATDPVRL KLFHTPRMVS 70 80 90 100 110 120 QGAHFAFCLP TKKPHYKPLL LSQNALDEFN LVQDQDLEKI LSGEKVYYSD SIFPYSTVYS 130 140 150 160 170 180 GFQFGSFAAQ LGDGRVVNLF DLKDKCSGQW QTFQLKGAGM TPFSRFADGK AVLRSSIREF 190 200 210 220 230 240 IMSEALHSIG IPSTRAMQLT LLPGTKAQRR NQEPCAVVCR FAPSWIRLGN FNLFRWRHDL 250 260 270 280 290 300 KGLIQLSDYC IEELFAGGTQ FEGKPDFNIF KRDFFPDTET KIDEQVEKDE TEVSTMTGDN 310 320 330 340 350 360 ISTLSKYDEF FRHVVSLNAN TVAHWQAYGF ANGVLNTDNT SIMGLTIDYG PFAFLDKFEP 370 380 390 400 410 420 SFTPNHDDTA KRYSFANQPS IIWWNLQQFA KDLACLLGPE ARDLELLLKG ELNSVDDALE 430 440 450 460 470 480 KTMIERVQKL VELSANEYKY VFTTRYAQIM SQRLGVDLDL EKCMSSTNLK DIEHAAEKAK 490 500 510 520 530 540 EFCDVIVEPL LDILQATKVD YNNFFIHLQN YKGPFFIKDK SDTATLFGAF DEEYLGMFFN 550 560 570 580 590 600 SKQLQQMAET EEAFAAGEKV FDANGELRLL NEKLQEIRNW TQDYLTLVPP TETAARASLA 610 620 630 640 650 660 KKANPLFVPR SWVLEEVVDD LMYSQRDGLQ DPSSELDTSA LKKLYLMSVN PYDRTKWDVT 670 680 LRPELETKWA DLSHQDDAKF MMQASCSS

References

[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI." Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W., Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D., Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E., Churcher C.M. , Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H., DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N., Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K., Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M., Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A., Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S., Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D., Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S., Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B., Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A., Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R., Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A., Vo D.H., Hani J. Nature 387:103-105(1997) [PubMed: 9169875] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	Z73578 Genomic DNA. Translation: CAA97937.1.
PIR	S65241.
RefSeq	NP_015102.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:2001N.
IntAct	Q08968.
Genome annotation databases
Ensembl	YPL222W. Saccharomyces cerevisiae. [Contig view]
GeneID	855879.
GenomeReviews	Gene locus YPL222W in contig U00094_GR.
KEGG	sce:YPL222W.
NMPDR	fig|4932.3.peg.6229.
Organism-specific databases
CYGD	YPL222w.
SGD	S000006143. YPL222W.
Yeast-GFP	Search...
Phylogenomic databases
HOGENOM	Q08968.
Gene expression databases
ArrayExpress	Q08968.
GermOnline	YPL222W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR003846. UPF0061. [Graphical view]
Pfam	PF02696. UPF0061. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
LinkHub	Q08968.
NextBio	980529.

Entry information

Entry name

YP222_YEAST

Accession

Primary (citable) accession number: Q08968

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	November 1, 1996
Last modified:	November 4, 2008
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)