Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q08968 (FMP40_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
UPF0061 protein FMP40
Gene names
Name:FMP40
Ordered Locus Names:YPL222W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length688 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Mitochondrion Ref.3 Ref.5.

Induction

Expression is regulated by zinc levels. Ref.6

Miscellaneous

Present with 2430 molecules/cell in log phase SD medium. Ref.4

Sequence similarities

Belongs to the UPF0061 (SELO) family.

Ontologies

Keywords
   Cellular componentMitochondrion
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular componentmitochondrion

Inferred from direct assay Ref.3Ref.5. Source: SGD

   Molecular functionprotein binding

Inferred from physical interaction. Source: IntAct

Complete GO annotation...

Binary interactions

With

Entry

#Exp.

IntAct

Notes

PRP40P332032EBI-29375,EBI-701

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 688688UPF0061 protein FMP40
PRO_0000121401

Sequences

Sequence LengthMass (Da)Tools
Q08968 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 7C56CD503ED24B1E

FASTA68878,313
        10         20         30         40         50         60 
MGEKRTIIKA LKNSAASHFI KKLTADTSLS SIQEAINVVQ QYNATDPVRL KLFHTPRMVS 

        70         80         90        100        110        120 
QGAHFAFCLP TKKPHYKPLL LSQNALDEFN LVQDQDLEKI LSGEKVYYSD SIFPYSTVYS 

       130        140        150        160        170        180 
GFQFGSFAAQ LGDGRVVNLF DLKDKCSGQW QTFQLKGAGM TPFSRFADGK AVLRSSIREF 

       190        200        210        220        230        240 
IMSEALHSIG IPSTRAMQLT LLPGTKAQRR NQEPCAVVCR FAPSWIRLGN FNLFRWRHDL 

       250        260        270        280        290        300 
KGLIQLSDYC IEELFAGGTQ FEGKPDFNIF KRDFFPDTET KIDEQVEKDE TEVSTMTGDN 

       310        320        330        340        350        360 
ISTLSKYDEF FRHVVSLNAN TVAHWQAYGF ANGVLNTDNT SIMGLTIDYG PFAFLDKFEP 

       370        380        390        400        410        420 
SFTPNHDDTA KRYSFANQPS IIWWNLQQFA KDLACLLGPE ARDLELLLKG ELNSVDDALE 

       430        440        450        460        470        480 
KTMIERVQKL VELSANEYKY VFTTRYAQIM SQRLGVDLDL EKCMSSTNLK DIEHAAEKAK 

       490        500        510        520        530        540 
EFCDVIVEPL LDILQATKVD YNNFFIHLQN YKGPFFIKDK SDTATLFGAF DEEYLGMFFN 

       550        560        570        580        590        600 
SKQLQQMAET EEAFAAGEKV FDANGELRLL NEKLQEIRNW TQDYLTLVPP TETAARASLA 

       610        620        630        640        650        660 
KKANPLFVPR SWVLEEVVDD LMYSQRDGLQ DPSSELDTSA LKKLYLMSVN PYDRTKWDVT 

       670        680 
LRPELETKWA DLSHQDDAKF MMQASCSS 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI."
Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W., Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D., Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E., Churcher C.M. expand/collapse author list , Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H., DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N., Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K., Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M., Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A., Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S., Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D., Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S., Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B., Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A., Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R., Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A., Vo D.H., Hani J.
Nature 387:103-105(1997) [PubMed: 9169875] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204511 / S288c / AB972.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed: 14562095] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[4]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed: 14562106] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[5]"The proteome of Saccharomyces cerevisiae mitochondria."
Sickmann A., Reinders J., Wagner Y., Joppich C., Zahedi R.P., Meyer H.E., Schoenfisch B., Perschil I., Chacinska A., Guiard B., Rehling P., Pfanner N., Meisinger C.
Proc. Natl. Acad. Sci. U.S.A. 100:13207-13212(2003) [PubMed: 14576278] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.
Strain: ATCC 76625 / YPH499.
[6]"Acetaldehyde addition throughout the growth phase alleviates the phenotypic effect of zinc deficiency in Saccharomyces cerevisiae."
Cheraiti N., Sauvage F.-X., Salmon J.-M.
Appl. Microbiol. Biotechnol. 77:1093-1109(2008) [PubMed: 17938904] [Abstract]
Cited for: INDUCTION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z73578 Genomic DNA. Translation: CAA97937.1.
BK006949 Genomic DNA. Translation: DAA11214.1.
PIRS65241.
RefSeqNP_015102.1. NM_001184036.1.

3D structure databases

ProteinModelPortalQ08968.
ModBaseSearch...

Protein-protein interaction databases

DIPDIP-2001N.
IntActQ08968. 6 interactions.
MINTMINT-393256.
STRINGQ08968.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYPL222W; YPL222W; YPL222W.
GeneID855879.
KEGGsce:YPL222W.
NMPDRfig|4932.3.peg.6229.

Organism-specific databases

CYGDYPL222w.
SGDS000006143. FMP40.

Phylogenomic databases

eggNOGfuNOG06676.
GeneTreeEFGT00050000005006.
HOGENOMHBG683993.
OMANAECVAY.
OrthoDBEOG4H49C9.

Gene expression databases

ArrayExpressQ08968.
GenevestigatorQ08968.
GermOnlineYPL222W. Saccharomyces cerevisiae.

Family and domain databases

InterProIPR003846. UPF0061.
[Graphical view]
PANTHERPTHR12153. PTHR12153. 1 hit.
PfamPF02696. UPF0061. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio980529.

Entry information

Entry nameFMP40_YEAST
AccessionPrimary (citable) accession number: Q08968
Secondary accession number(s): D6W3E8
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: December 14, 2011
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Uncharacterized protein families (UPF)

List of uncharacterized protein family (UPF) entries

SIMILARITY comments

Index of protein domains and families