Q088C3 (F16PA_SHEFN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Fructose-1,6-bisphosphatase class 1
Short name=FBPase class 1
EC=3.1.3.11

Alternative name(s):
D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1

Gene names

Name:	fbp
Ordered Locus Names:	Sfri_0531

Organism

Shewanella frigidimarina (strain NCIMB 400) [Complete proteome] [HAMAP]

Taxonomic identifier

318167 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	330 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855
Cofactor	Binds 2 magnesium ions per subunit By similarity. HAMAP MF_01855
Pathway	Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_01855
Subunit structure	Homotetramer By similarity. HAMAP MF_01855
Subcellular location	Cytoplasm Potential HAMAP MF_01855.
Sequence similarities	Belongs to the FBPase class 1 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Cellular component	Cytoplasm
Ligand	Magnesium Metal-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	fructose 1,6-bisphosphate 1-phosphatase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 330	330	Fructose-1,6-bisphosphatase class 1 HAMAP MF_01855		PRO_0000364704
Regions
	Region	106 – 109	4	Substrate binding By similarity
Sites
	Metal binding	84	1	Magnesium 1 By similarity
	Metal binding	103	1	Magnesium 1 By similarity
	Metal binding	103	1	Magnesium 2 By similarity
	Metal binding	105	1	Magnesium 1; via carbonyl oxygen By similarity
	Metal binding	106	1	Magnesium 2 By similarity
	Metal binding	268	1	Magnesium 2 By similarity
	Binding site	196	1	Substrate By similarity
	Binding site	262	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q088C3 [UniParc]. Last modified October 31, 2006. Version 1. Checksum: B6A892D3947824B2	FASTA	330	35,736
	10 20 30 40 50 60 MQTLAQTLSV QAVNASLTQL LLTLADTSKA ISGAVRHGAL AGVLGATEQE NIQGETQKKL 70 80 90 100 110 120 DVITNDMLKD ALKADGNVRG LASEEEDYVV EVNAKGEYLV CFDPLDGSSN IDINSLVGTI 130 140 150 160 170 180 FSVLPAPAGE LNEQSFLQAG RKQVAAGYVL YGPSTMMALT TGQGTQFYTL APDSQEFLLT 190 200 210 220 230 240 DDSVQITPDT AEFAINMSNQ RFWEAPMQTY IADLLLGEIG PREQSFNMRW IAAMVGDVHR 250 260 270 280 290 300 VLCRGGIFSY PTDNKNPAKP FKLRLMYEAN PMALLVEQAG GKASTGYETI LDIQPTEIHQ 310 320 330 RVAVILGSAN EVDTCLSYHG IDYSEEPSID

References

[1]

"Complete sequence of Shewanella frigidimarina NCIMB 400." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Fredrickson J.K., Kolker E., McCuel L.A., DiChristina T., Nealson K.H., Newman D., Tiedje J.M. , Zhou J., Romine M.F., Culley D.E., Serres M., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCIMB 400.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000447 Genomic DNA. Translation: ABI70392.1.
RefSeq	YP_749230.1. NC_008345.1.
3D structure databases
ProteinModelPortal	Q088C3.
ModBase	Search...
Protein-protein interaction databases
STRING	Q088C3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4276951.
GenomeReviews	Gene locus Sfri_0531 in contig CP000447_GR.
KEGG	sfr:Sfri_0531.
NMPDR	fig|318167.10.peg.506.
PATRIC	23494849. VBISheFri14343_0549.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0158.
HOGENOM	HBG731261.
OMA	ANEVDTC.
PhylomeDB	Q088C3.
ProtClustDB	PRK09293.
Family and domain databases
HAMAP	MF_01855. FBPase_class1. [Tree]
InterPro	IPR000146. FBPase_class-1/SBPase. [Graphical view]
KO	K03841.
PANTHER	PTHR11556. In_FB_phphtase. 1 hit.
Pfam	PF00316. FBPase. 1 hit. [Graphical view]
PIRSF	PIRSF000904. FBPtase_SBPase. 1 hit.
PRINTS	PR00115. F16BPHPHTASE.
PROSITE	PS00124. FBPASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F16PA_SHEFN

Accession

Primary (citable) accession number: Q088C3

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	October 31, 2006
Last modified:	January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program