Reviewed, UniProtKB/Swiss-Prot Q08888 (SYR_BUCAP)

Names and origin

Protein names

Recommended name:
    Arginyl-tRNA synthetase
    EC=6.1.1.19
Alternative name(s):
    Arginine--tRNA ligase
      Short name=ArgRS

Gene names

Name:	argS
Ordered Locus Names:	BUsg_237

Organism

Buchnera aphidicola subsp. Schizaphis graminum [Complete proteome] [HAMAP]

Taxonomic identifier

98794 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	580 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP MF_00123
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm. HAMAP MF_00123
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 580	580	Arginyl-tRNA synthetase HAMAP MF_00123		PRO_0000151540
Regions
	Motif	123 – 133	11	"HIGH" region HAMAP MF_00123

Sequences

	Sequence		Length	Mass (Da)
	Q08888-1 [UniParc]. Last modified August 30, 2002. Version 2. Checksum: CFE972DC5DC43ED5	FASTA	580	68,043
	10 20 30 40 50 60 MNIKYLIKKD IEQALIKINS NYTYEVFIIS SKKIELGHYQ VDNLMKISSR LKIKPYKLFQ 70 80 90 100 110 120 KILILIEKKK IYKKIIFSHP GFINIFIKNE WLSEKLEIPF ISSRLGVKYI YPKKNIVIDY 130 140 150 160 170 180 SSPNIAKEMH VGHLRSTIIG DVTVRILEFL GQKVIRANHI GDWGTQFGIL IAYLEDKKLL 190 200 210 220 230 240 KKLKKNLLSL QDLDNIYCQS KKQYNSNELF SKKSREFVVK LQNGDQYCCA IWKKLVSITM 250 260 270 280 290 300 LENYKIYKKL NVTLEEKHTM GESFYNPMLP KIVEDLKKQK IAIEKNGAVI VFLDEFKNRM 310 320 330 340 350 360 GDSMGVIIRK KDKGFLYSTT DIACLKYRYQ NLHADRIIYY TDSRQYQHLL QSWTIAEKAN 370 380 390 400 410 420 YISKNLLLEH HMFGMMLSKN RRPFKTRDGN TIKLSNLLNE SINRATNLIQ KKQPNLCKKK 430 440 450 460 470 480 LIKLGEIIGI SAVKYSDLSK NRNTNYIFDW DKMLSFEGNT APYIQYAYTR IISILKKSNI 490 500 510 520 530 540 PLHKIKMKII LNEESEINLA IKILEFEEII LLIAKNGTPH IMCKYLYQLS TYFSHFYENC 550 560 570 580 SILFSEKIKI RKSRIKLSFL TAKTIKKGLN LLGIKTIKKM

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"50 million years of genomic stasis in endosymbiotic bacteria." Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E. Science 296:2376-2379(2002) [PubMed: 12089438] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"Buchnera aphidicola (a prokaryotic endosymbiont of aphids) contains a putative 16S rRNA operon unlinked to the 23S rRNA-encoding gene: sequence determination, and promoter and terminator analysis." Munson M.A., Baumann L., Baumann P. Gene 137:171-178(1993) [PubMed: 7507875] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-131.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE013218 Genomic DNA. Translation: AAM67796.1. L18927 Genomic DNA. Translation: AAA17432.1.
PIR	I40591.
RefSeq	NP_660585.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1005438.
GenomeReviews	Gene locus BUsg_237 in contig AE013218_GR.
KEGG	bas:BUsg237.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q08888.
OMA	Q08888. HMGFGTM.
Enzyme and pathway databases
BioCyc	BAPH198804:BUSG237-MON.
Family and domain databases
HAMAP	MF_00123. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-synth_Ic. IPR015945. Arg-tRNA-synth_Ic_core. IPR005148. Arg-tRNA-synth_Ic_N. IPR008909. DALR_anticod_bd. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PANTHER	PTHR11956. Arg_tRNA-synt_1c. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
TIGRFAMs	TIGR00456. argS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYR_BUCAP

Accession

Primary (citable) accession number: Q08888

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1994
Last sequence update:	August 30, 2002
Last modified:	June 16, 2009
This is version 72 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)