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Q08888 (SYR_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 106. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:BUsg_237
OrganismBuchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]
Taxonomic identifier198804 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length580 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 580580Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000151540

Regions

Motif123 – 13311"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q08888 [UniParc].

Last modified August 30, 2002. Version 2.
Checksum: CFE972DC5DC43ED5

FASTA58068,043
        10         20         30         40         50         60 
MNIKYLIKKD IEQALIKINS NYTYEVFIIS SKKIELGHYQ VDNLMKISSR LKIKPYKLFQ 

        70         80         90        100        110        120 
KILILIEKKK IYKKIIFSHP GFINIFIKNE WLSEKLEIPF ISSRLGVKYI YPKKNIVIDY 

       130        140        150        160        170        180 
SSPNIAKEMH VGHLRSTIIG DVTVRILEFL GQKVIRANHI GDWGTQFGIL IAYLEDKKLL 

       190        200        210        220        230        240 
KKLKKNLLSL QDLDNIYCQS KKQYNSNELF SKKSREFVVK LQNGDQYCCA IWKKLVSITM 

       250        260        270        280        290        300 
LENYKIYKKL NVTLEEKHTM GESFYNPMLP KIVEDLKKQK IAIEKNGAVI VFLDEFKNRM 

       310        320        330        340        350        360 
GDSMGVIIRK KDKGFLYSTT DIACLKYRYQ NLHADRIIYY TDSRQYQHLL QSWTIAEKAN 

       370        380        390        400        410        420 
YISKNLLLEH HMFGMMLSKN RRPFKTRDGN TIKLSNLLNE SINRATNLIQ KKQPNLCKKK 

       430        440        450        460        470        480 
LIKLGEIIGI SAVKYSDLSK NRNTNYIFDW DKMLSFEGNT APYIQYAYTR IISILKKSNI 

       490        500        510        520        530        540 
PLHKIKMKII LNEESEINLA IKILEFEEII LLIAKNGTPH IMCKYLYQLS TYFSHFYENC 

       550        560        570        580 
SILFSEKIKI RKSRIKLSFL TAKTIKKGLN LLGIKTIKKM 

« Hide

References

« Hide 'large scale' references
[1]"50 million years of genomic stasis in endosymbiotic bacteria."
Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.
Science 296:2376-2379(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Sg.
[2]"Buchnera aphidicola (a prokaryotic endosymbiont of aphids) contains a putative 16S rRNA operon unlinked to the 23S rRNA-encoding gene: sequence determination, and promoter and terminator analysis."
Munson M.A., Baumann L., Baumann P.
Gene 137:171-178(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-131.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE013218 Genomic DNA. Translation: AAM67796.1.
L18927 Genomic DNA. Translation: AAA17432.1.
PIRI40591.
RefSeqNP_660585.1. NC_004061.1.

3D structure databases

ProteinModelPortalQ08888.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING198804.BUsg237.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM67796; AAM67796; BUsg_237.
GeneID1005438.
KEGGbas:BUsg237.
PATRIC21247269. VBIBucAph100086_0248.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
KOK01887.
OMAKCFDILG.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycBAPH198804:GHMG-247-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_BUCAP
AccessionPrimary (citable) accession number: Q08888
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: August 30, 2002
Last modified: May 14, 2014
This is version 106 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Buchnera aphidicola (subsp. Schizaphis graminum)

Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries