Reviewed, UniProtKB/Swiss-Prot Q08871 (LLCD_SYNY3)

Names and origin

Protein names

Recommended name:
    Linoleoyl-CoA desaturase
    EC=1.14.19.3
Alternative name(s):
    Delta(6)-desaturase

Gene names

Name:	des6
Ordered Locus Names:	sll0262

Organism

Synechocystis sp. (strain PCC 6803) [Complete proteome] [HAMAP]

Taxonomic identifier

1148 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechocystis

Protein attributes

Sequence length	359 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Predicted.

General annotation (Comments)

Catalytic activity	Linoleoyl-CoA + AH2 + O2 = gamma-linolenoyl-CoA + A + 2 H2O.
Cofactor	Iron.

Ontologies

Keywords
Ligand	Iron
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid metabolic process Inferred from electronic annotation. Source: InterPro oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW linoleoyl-CoA desaturase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 359	359	Linoleoyl-CoA desaturase		PRO_0000185432

Sequences

	Sequence		Length	Mass (Da)
	Q08871-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 33FB165AEB98C05F	FASTA	359	41,425
	10 20 30 40 50 60 MLTAERIKFT QKRGFRRVLN QRVDAYFAEH GLTQRDNPSM YLKTLIIVLW LFSAWAFVLF 70 80 90 100 110 120 APVIFPVRLL GCMVLAIALA AFSFNVGHDA NHNAYSSNPH INRVLGMTYD FVGLSSFLWR 130 140 150 160 170 180 YRHNYLHHTY TNILGHDVEI HGDGAVRMSP EQEHVGIYRF QQFYIWGLYL FIPFYWFLYD 190 200 210 220 230 240 VYLVLNKGKY HDHKIPPFQP LELASLLGIK LLWLGYVFGL PLALGFSIPE VLIGASVTYM 250 260 270 280 290 300 TYGIVVCTIF MLAHVLESTE FLTPDGESGA IDDEWAICQI RTTANFATNN PFWNWFCGGL 310 320 330 340 350 NHQVTHHLFP NICHIHYPQL ENIIKDVCQE FGVEYKVYPT FKAAIASNYR WLEAMGKAS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Isolation of a delta 6-desaturase gene from the cyanobacterium Synechocystis sp. strain PCC 6803 by gain-of-function expression in Anabaena sp. strain PCC 7120." Reddy A.S., Nuccio M.L., Gross L.M., Thomas T.L. Plant Mol. Biol. 22:293-300(1993) [PubMed: 8389613] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	L11421 Genomic DNA. Translation: AAA27286.1. BA000022 Genomic DNA. Translation: BAA18502.1.
RefSeq	NP_441824.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	Q08871. 3 interactions.
STRING	Q08871.
Genome annotation databases
GeneID	953137.
GenomeReviews	Gene locus sll0262 in contig BA000022_GR.
KEGG	syn:sll0262.
NMPDR	fig|1148.1.peg.1925.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG284193.
OMA	NRFLSAS.
Enzyme and pathway databases
BioCyc	SSP1148:SLL0262-MON.
Family and domain databases
InterPro	IPR005804. Fatty_acid_desaturase-1. [Graphical view]
Pfam	PF00487. FA_desaturase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

LLCD_SYNY3

Accession

Primary (citable) accession number: Q08871

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	December 15, 2009
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)