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Q08849 (STX3_RAT) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 92. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Syntaxin-3
Gene names
Name:Stx3
Synonyms:Stx3a
OrganismRattus norvegicus (Rat) [Reference proteome]
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length289 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Potentially involved in docking of synaptic vesicles at presynaptic active zones.

Subcellular location

Membrane; Single-pass type IV membrane protein Potential.

Tissue specificity

Heart, spleen, lung and kidney.

Sequence similarities

Belongs to the syntaxin family.

Contains 1 t-SNARE coiled-coil homology domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 289289Syntaxin-3
PRO_0000210201

Regions

Topological domain1 – 263263Cytoplasmic Potential
Transmembrane264 – 28421Helical; Anchor for type IV membrane protein; Potential
Topological domain285 – 2895Extracellular Potential
Domain191 – 25363t-SNARE coiled-coil homology
Coiled coil32 – 11180 Potential

Sequences

Sequence LengthMass (Da)Tools
Q08849 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 4A8EAFD4684EEE6F

FASTA28933,257
        10         20         30         40         50         60 
MKDRLEQLKA KQLTQDDDTD EVEIAIDNTA FMDEFFSEIE ETRLNIDKIS EHVEEAKKLY 

        70         80         90        100        110        120 
SIILSAPIPE PKTKDDLEQL TTEIKKRANN VRNKLKSMEK HIEEDEVRSS ADLRIRKSQH 

       130        140        150        160        170        180 
SVLSRKFVEV MTKYNEAQVD FRERSKGRIQ RQLEITGKKT TDEELEEMLE SGNPAIFTSG 

       190        200        210        220        230        240 
IIDSQISKQA LSEIEGRHKD IVRLESSIKE LHDMFMDIAM LVENQGEMLD NIELNVMHTV 

       250        260        270        280 
DHVEKARDET KRAMKYQGQA RKKLIIIIVI VVVLLGILAL IIGLSVGLK

« Hide

References

[1]"The syntaxin family of vesicular transport receptors."
Bennett M.K., Garcia-Arraras J.E., Elferink L.A., Peterson K.E., Fleming A.M., Hazuka C.D., Scheller R.H.
Cell 74:863-873(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		L20820 mRNA. Translation: AAA03045.1.
IPIIPI00204705.
PIRD48213.
RefSeqNP_112386.1. NM_031124.1.
UniGeneRn.10951.

3D structure databases

ProteinModelPortalQ08849.
SMRQ08849. Positions 31-246.
ModBaseSearch...

Proteomic databases

PaxDbQ08849.
PRIDEQ08849.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSRNOT00000028535; ENSRNOP00000028535; ENSRNOG00000021013.
GeneID81802.
KEGGrno:81802.
UCSCRGD:621005. rat.

Organism-specific databases

CTD6809.
RGD621005. Stx3.

Phylogenomic databases

eggNOGCOG5074.
GeneTreeENSGT00550000074334.
HOGENOMHOG000286023.
HOVERGENHBG000497.
InParanoidQ08849.
KOK08486.

Gene expression databases

ArrayExpressQ08849.
GenevestigatorQ08849.
GermOnlineENSRNOG00000021013. Rattus norvegicus.

Family and domain databases

InterProIPR015708. Syntaxin-3.
IPR006012. Syntaxin/epimorphin_CS.
IPR006011. Syntaxin_N.
IPR010989. t-SNARE.
IPR000727. T_SNARE_dom.
[Graphical view]
PANTHERPTHR19957:SF34. PTHR19957:SF34. 1 hit.
PfamPF05739. SNARE. 1 hit.
PF00804. Syntaxin. 1 hit.
[Graphical view]
SMARTSM00503. SynN. 1 hit.
SM00397. t_SNARE. 1 hit.
[Graphical view]
SUPFAMSSF47661. t-snare. 1 hit.
PROSITEPS00914. SYNTAXIN. 1 hit.
PS50192. T_SNARE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio615655.

Entry information

Entry nameSTX3_RAT
AccessionPrimary (citable) accession number: Q08849
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: April 3, 2013
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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