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Protein

Meiotic sister-chromatid recombination protein 6, mitochondrial

Gene

MSC6

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May be involved in the control of meiotic sister-chromatid recombination.1 Publication

GO - Biological processi

  • reciprocal meiotic recombination Source: SGD
Complete GO annotation...

Keywords - Biological processi

DNA recombination, Meiosis

Enzyme and pathway databases

BioCyciYEAST:G3O-33825-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Meiotic sister-chromatid recombination protein 6, mitochondrial
Gene namesi
Name:MSC6
Ordered Locus Names:YOR354C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XV

Organism-specific databases

EuPathDBiFungiDB:YOR354C.
SGDiS000005881. MSC6.

Subcellular locationi

GO - Cellular componenti

  • mitochondrial matrix Source: SGD
  • mitochondrion Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 3030MitochondrionSequence analysisAdd
BLAST
Chaini31 – 692662Meiotic sister-chromatid recombination protein 6, mitochondrialPRO_0000042820Add
BLAST

Proteomic databases

MaxQBiQ08818.
TopDownProteomicsiQ08818.

Interactioni

Protein-protein interaction databases

BioGridi34739. 58 interactions.
DIPiDIP-4057N.
MINTiMINT-525788.

Structurei

3D structure databases

ProteinModelPortaliQ08818.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transit peptide

Phylogenomic databases

InParanoidiQ08818.
OMAiKICENEE.
OrthoDBiEOG7CNZS4.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q08818-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSHNALRAF DCSKVIISRR CLTSSTSIYQ QSSVHLQETD DGHSGNREKH
60 70 80 90 100
VSPFERVQNL AADLKNELKA PDSDINEVFN DFKDKIESLK QKLRNPSPME
110 120 130 140 150
RSHLLANFSS DLLQELSYRS KNMTLDPYQV LNTLCQYKLA RSQHFTIVLK
160 170 180 190 200
YLLYNQSPQD VIALWVKYLE TISENPVILL QNSSSRAHMQ NIAITTIAYL
210 220 230 240 250
SLPENTVDIN ILYKILQIDR KMGQVLPFNM IRRMLSTEFS SLERRDVIIK
260 270 280 290 300
NLNTLYYQYT VQDSDHFLSQ IENAPRWIDL RDLYGQYNKL EGEKNVEIIS
310 320 330 340 350
KFMDKFIDLD KPDQVVTIYN QYSKVFPNST SLKDCLLRAV SHLRAKSSKE
360 370 380 390 400
KLDRILAVWN SVIKPGDNIK NTSYATLVNA LTDSGNFNHL KEFWEEELPK
410 420 430 440 450
KFKKDPIVKE AFLLALCQTS PLKYDQVKGE LAETVKTKKL FNKVLLLMLD
460 470 480 490 500
DEKVSEEQFN TFYYNHYPSD GVLPPTLDTL SIKMYANYKF QAEDTRPQFD
510 520 530 540 550
LLQSVSINPT DYEKVEKITK AFISVCPTVE PIRQLYKQLG THLNARNYAD
560 570 580 590 600
FISAEFNKPD GTVAEAKNLF SDFLSYQKTR KRNVDNTPLN ALLLGFCDKL
610 620 630 640 650
YKSKHSEYVP YIEKYYNLAK DSSIRVSNLA VSKILFNLAT FARNTQQLSD
660 670 680 690
KEVAFINQFM RDLGTNEGFR PNPKDIQILK ECDGITVPEK LT
Length:692
Mass (Da):79,947
Last modified:November 1, 1996 - v1
Checksum:i23C58EB31249DA31
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z75262 Genomic DNA. Translation: CAA99683.1.
BK006948 Genomic DNA. Translation: DAA11115.1.
PIRiS67266.
RefSeqiNP_014999.1. NM_001183774.1.

Genome annotation databases

EnsemblFungiiYOR354C; YOR354C; YOR354C.
GeneIDi854536.
KEGGisce:YOR354C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z75262 Genomic DNA. Translation: CAA99683.1.
BK006948 Genomic DNA. Translation: DAA11115.1.
PIRiS67266.
RefSeqiNP_014999.1. NM_001183774.1.

3D structure databases

ProteinModelPortaliQ08818.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi34739. 58 interactions.
DIPiDIP-4057N.
MINTiMINT-525788.

Proteomic databases

MaxQBiQ08818.
TopDownProteomicsiQ08818.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYOR354C; YOR354C; YOR354C.
GeneIDi854536.
KEGGisce:YOR354C.

Organism-specific databases

EuPathDBiFungiDB:YOR354C.
SGDiS000005881. MSC6.

Phylogenomic databases

InParanoidiQ08818.
OMAiKICENEE.
OrthoDBiEOG7CNZS4.

Enzyme and pathway databases

BioCyciYEAST:G3O-33825-MONOMER.

Miscellaneous databases

PROiQ08818.

Family and domain databases

ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV."
    Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J., Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A., Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B., Dang V.-D.
    , de Haan M., Delius H., Durand P., Fairhead C., Feldmann H., Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E., Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U., Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B., Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A., Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C., Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G., Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B., Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F., Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E., Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I., Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H., Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.
    Nature 387:98-102(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. "Genetic control of recombination partner preference in yeast meiosis. Isolation and characterization of mutants elevated for meiotic unequal sister-chromatid recombination."
    Thompson D.A., Stahl F.W.
    Genetics 153:621-641(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  4. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  6. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    Strain: ATCC 76625 / YPH499.

Entry informationi

Entry nameiMSC6_YEAST
AccessioniPrimary (citable) accession number: Q08818
Secondary accession number(s): D6W349
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 1, 1996
Last modified: July 6, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 7250 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XV
    Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.