Q08816 (YO352_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein YOR352W

Gene names

Ordered Locus Names:

YOR352W

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	343 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Cytoplasm. Nucleus Ref.3.
Miscellaneous	Present with 3510 molecules/cell in log phase SD medium.

Ontologies

Keywords
Cellular component	Cytoplasm Nucleus
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from direct assay Ref.3. Source: SGD holo TFIIH complex Inferred from direct assay PubMed 22411836. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 343	343	Uncharacterized protein YOR352W		PRO_0000245290
Amino acid modifications
	Modified residue	71	1	Phosphothreonine Ref.6
	Modified residue	105	1	Phosphoserine Ref.5 Ref.7
	Modified residue	108	1	Phosphoserine Ref.7
	Modified residue	109	1	Phosphoserine Ref.7
	Modified residue	111	1	Phosphothreonine Ref.7
	Modified residue	131	1	Phosphoserine Ref.6 Ref.7
	Modified residue	342	1	Phosphoserine Ref.5 Ref.7

Sequences

	Sequence		Length	Mass (Da)
	Q08816 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: E52A1C2DF5A5141A	FASTA	343	39,275
	10 20 30 40 50 60 MSEPNTPLHA QPNEQLDLNN LNDLDEKDID DLNLDPNSDV EISADSGDVV NSNIDNVIWQ 70 80 90 100 110 120 RNCNKKRRYH TPEFNDVYNE TNNTINDVTM LDDVDDFQPR INVSSPFSSA TKLSELLPND 130 140 150 160 170 180 HNGTSHPRRL SMSQQSKFIS YVDDQLLQIQ RKFVQSRGLN IKNGYASLTP LLQDLKTLVD 190 200 210 220 230 240 FVWYSIAHVP NSDYLLQSEE KRHCPDSRNP KDTCGYSSYF GQGSYLIKIA DDLIDYVEKF 250 260 270 280 290 300 TFKNMEDSEI NDTLSKLFKL FFILDRIFVI LTDDNDNCKE VPKTSSASKN IAGLNGTDIV 310 320 330 340 RLKGIAERTR VRLPIFLESQ GIHGYHYELS KIYEGFLDHA NSF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XV." Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J., Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A., Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B., Dang V.-D. , de Haan M., Delius H., Durand P., Fairhead C., Feldmann H., Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E., Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U., Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B., Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A., Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C., Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G., Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B., Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F., Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E., Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I., Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H., Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K. Nature 387:98-102(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[4]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[5]	"Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway." Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J., Mann M., Jensen O.N. Mol. Cell. Proteomics 4:310-327(2005) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-105 AND SER-342, MASS SPECTROMETRY. Strain: YAL6B.
[6]	"Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases." Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H. Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-71 AND SER-131, MASS SPECTROMETRY.
[7]	"A multidimensional chromatography technology for in-depth phosphoproteome analysis." Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H. Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-105; SER-108; SER-109; THR-111; SER-131 AND SER-342, MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z75260 Genomic DNA. Translation: CAA99681.1. BK006948 Genomic DNA. Translation: DAA11113.1.
PIR	S67264.
RefSeq	NP_014997.1. NM_001183772.1.
3D structure databases
ProteinModelPortal	Q08816.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-5639N.
IntAct	Q08816. 7 interactions.
MINT	MINT-560176.
STRING	4932.YOR352W.
Proteomic databases
PaxDb	Q08816.
PeptideAtlas	Q08816.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YOR352W; YOR352W; YOR352W.
GeneID	854534.
KEGG	sce:YOR352W.
Organism-specific databases
CYGD	YOR352w.
SGD	S000005879. YOR352W.
Phylogenomic databases
eggNOG	NOG45793.
HOGENOM	HOG000141966.
OMA	IQRKFVQ.
OrthoDB	EOG4PP1SB.
Gene expression databases
Genevestigator	Q08816.
GermOnline	YOR352W. Saccharomyces cerevisiae.
Family and domain databases
ProtoNet	Search...
Other
NextBio	976925.

Entry information

Entry name

YO352_YEAST

Accession

Primary (citable) accession number: Q08816
Secondary accession number(s): D6W347

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 11, 2006
Last sequence update:	November 1, 1996
Last modified:	April 3, 2013
This is version 74 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program