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Q08743 (YO292_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Vacuolar membrane protein YOR292C
Gene names
Ordered Locus Names:YOR292C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length309 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Vacuole membrane; Multi-pass membrane protein Ref.4.

Post-translational modification

N-glycosylated.

Sequence similarities

Belongs to the peroxisomal membrane protein PXMP2/4 family.

Ontologies

Keywords
   Cellular componentMembrane
Vacuole
   DomainTransmembrane
Transmembrane helix
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

vacuolar membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 309309Vacuolar membrane protein YOR292C
PRO_0000245252

Regions

Topological domain1 – 5252Vacuolar Potential
Transmembrane53 – 7321Helical; Potential
Topological domain74 – 818Cytoplasmic Potential
Transmembrane82 – 10221Helical; Potential
Topological domain103 – 18381Vacuolar Potential
Transmembrane184 – 20421Helical; Potential
Topological domain205 – 22521Cytoplasmic Potential
Transmembrane226 – 24621Helical; Potential
Topological domain247 – 26014Vacuolar Potential
Transmembrane261 – 28121Helical; Potential
Topological domain282 – 30928Cytoplasmic Potential

Amino acid modifications

Glycosylation191N-linked (GlcNAc...) Potential
Glycosylation1211N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q08743 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: A3BD32893F595536

FASTA30936,195
        10         20         30         40         50         60 
MPLQLFGRDQ IVVHYDNGNM SNDDQNHQSV LGSWTRRAAA ALRTLMNKRI QRITLTHWLL 

        70         80         90        100        110        120 
LVIWVTSLWK FTSHYRQLYA NSAVFATLCT NILLFGISDI LAQSIACFYS YHVDPIPQIL 

       130        140        150        160        170        180 
NDTFHHVQNN RDVENGGGYE SDELSIFNDF TSEHSSYTDN DDYPELDRPL ATFKTDTFDF 

       190        200        210        220        230        240 
FRWGCFMFWG FFISFFQAPW YKFLNFFYTE DPTVVQVFER VLSDQLLYSP ISLYCFFMFS 

       250        260        270        280        290        300 
NYVMEGGDKD TLGKKIQRLY ISTLGCNYLV WPMVQFINFL IMPRDFQAPF SSSVGVVWNC 


FLSMRNASK 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of a 36.2 kb fragment from the right arm of yeast chromosome XV reveals 19 open reading frames including SNF2 (5' end), CPA1, SLY41, a putative transport ATPase, a putative ribosomal protein and an SNF2 homologue."
Poirey R., Cziepluch C., Tobiasch E., Pujol A., Kordes E., Jauniaux J.-C.
Yeast 13:479-482(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XV."
Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J., Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A., Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B., Dang V.-D. expand/collapse author list , de Haan M., Delius H., Durand P., Fairhead C., Feldmann H., Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E., Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U., Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B., Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A., Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C., Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G., Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B., Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F., Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E., Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I., Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H., Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.
Nature 387:98-102(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[5]"A global topology map of the Saccharomyces cerevisiae membrane proteome."
Kim H., Melen K., Oesterberg M., von Heijne G.
Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: ATCC 208353 / W303-1A.
[6]"Global analysis of the glycoproteome in Saccharomyces cerevisiae reveals new roles for protein glycosylation in eukaryotes."
Kung L.A., Tao S.-C., Qian J., Smith M.G., Snyder M., Zhu H.
Mol. Syst. Biol. 5:308-308(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z75200 Genomic DNA. Translation: CAA99520.1.
BK006948 Genomic DNA. Translation: DAA11056.1.
PIRS67196.
RefSeqNP_014935.3. NM_001183711.3.

3D structure databases

ProteinModelPortalQ08743.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid34680. 6 interactions.
DIPDIP-1733N.
IntActQ08743. 2 interactions.
MINTMINT-385832.
STRING4932.YOR292C.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYOR292C; YOR292C; YOR292C.
GeneID854467.
KEGGsce:YOR292C.

Organism-specific databases

CYGDYOR292c.
SGDS000005818. YOR292C.

Phylogenomic databases

eggNOGNOG260124.
HOGENOMHOG000246702.
OMANRLAGFM.
OrthoDBEOG79W9GZ.

Enzyme and pathway databases

BioCycYEAST:G3O-33777-MONOMER.

Gene expression databases

GenevestigatorQ08743.

Family and domain databases

InterProIPR007248. Mpv17_PMP22.
[Graphical view]
PANTHERPTHR11266. PTHR11266. 1 hit.
PfamPF04117. Mpv17_PMP22. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio976756.

Entry information

Entry nameYO292_YEAST
AccessionPrimary (citable) accession number: Q08743
Secondary accession number(s): D6W2Z0
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2006
Last sequence update: November 1, 1996
Last modified: February 19, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XV

Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families