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Protein

Vacuolar membrane protein YOR292C

Gene

YOR292C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciYEAST:G3O-33777-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Vacuolar membrane protein YOR292C
Gene namesi
Ordered Locus Names:YOR292C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311 Componenti: Chromosome XV

Organism-specific databases

CYGDiYOR292c.
SGDiS000005818. YOR292C.

Subcellular locationi

Vacuole membrane 1 Publication; Multi-pass membrane protein 1 Publication

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 5252VacuolarSequence AnalysisAdd
BLAST
Transmembranei53 – 7321HelicalSequence AnalysisAdd
BLAST
Topological domaini74 – 818CytoplasmicSequence Analysis
Transmembranei82 – 10221HelicalSequence AnalysisAdd
BLAST
Topological domaini103 – 18381VacuolarSequence AnalysisAdd
BLAST
Transmembranei184 – 20421HelicalSequence AnalysisAdd
BLAST
Topological domaini205 – 22521CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei226 – 24621HelicalSequence AnalysisAdd
BLAST
Topological domaini247 – 26014VacuolarSequence AnalysisAdd
BLAST
Transmembranei261 – 28121HelicalSequence AnalysisAdd
BLAST
Topological domaini282 – 30928CytoplasmicSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. vacuolar membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Vacuole

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 309309Vacuolar membrane protein YOR292CPRO_0000245252Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi19 – 191N-linked (GlcNAc...)Sequence Analysis
Glycosylationi121 – 1211N-linked (GlcNAc...)Sequence Analysis

Post-translational modificationi

N-glycosylated.1 Publication

Keywords - PTMi

Glycoprotein

Expressioni

Gene expression databases

GenevestigatoriQ08743.

Interactioni

Protein-protein interaction databases

BioGridi34680. 6 interactions.
DIPiDIP-1733N.
IntActiQ08743. 2 interactions.
MINTiMINT-385832.
STRINGi4932.YOR292C.

Structurei

3D structure databases

ProteinModelPortaliQ08743.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG260124.
HOGENOMiHOG000246702.
InParanoidiQ08743.
OMAiNRLAGFM.
OrthoDBiEOG79W9GZ.

Family and domain databases

InterProiIPR007248. Mpv17_PMP22.
[Graphical view]
PANTHERiPTHR11266. PTHR11266. 1 hit.
PfamiPF04117. Mpv17_PMP22. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q08743-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLQLFGRDQ IVVHYDNGNM SNDDQNHQSV LGSWTRRAAA ALRTLMNKRI
60 70 80 90 100
QRITLTHWLL LVIWVTSLWK FTSHYRQLYA NSAVFATLCT NILLFGISDI
110 120 130 140 150
LAQSIACFYS YHVDPIPQIL NDTFHHVQNN RDVENGGGYE SDELSIFNDF
160 170 180 190 200
TSEHSSYTDN DDYPELDRPL ATFKTDTFDF FRWGCFMFWG FFISFFQAPW
210 220 230 240 250
YKFLNFFYTE DPTVVQVFER VLSDQLLYSP ISLYCFFMFS NYVMEGGDKD
260 270 280 290 300
TLGKKIQRLY ISTLGCNYLV WPMVQFINFL IMPRDFQAPF SSSVGVVWNC

FLSMRNASK
Length:309
Mass (Da):36,195
Last modified:October 31, 1996 - v1
Checksum:iA3BD32893F595536
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z75200 Genomic DNA. Translation: CAA99520.1.
BK006948 Genomic DNA. Translation: DAA11056.1.
PIRiS67196.
RefSeqiNP_014935.3. NM_001183711.3.

Genome annotation databases

EnsemblFungiiYOR292C; YOR292C; YOR292C.
GeneIDi854467.
KEGGisce:YOR292C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z75200 Genomic DNA. Translation: CAA99520.1.
BK006948 Genomic DNA. Translation: DAA11056.1.
PIRiS67196.
RefSeqiNP_014935.3. NM_001183711.3.

3D structure databases

ProteinModelPortaliQ08743.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi34680. 6 interactions.
DIPiDIP-1733N.
IntActiQ08743. 2 interactions.
MINTiMINT-385832.
STRINGi4932.YOR292C.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYOR292C; YOR292C; YOR292C.
GeneIDi854467.
KEGGisce:YOR292C.

Organism-specific databases

CYGDiYOR292c.
SGDiS000005818. YOR292C.

Phylogenomic databases

eggNOGiNOG260124.
HOGENOMiHOG000246702.
InParanoidiQ08743.
OMAiNRLAGFM.
OrthoDBiEOG79W9GZ.

Enzyme and pathway databases

BioCyciYEAST:G3O-33777-MONOMER.

Miscellaneous databases

NextBioi976756.

Gene expression databases

GenevestigatoriQ08743.

Family and domain databases

InterProiIPR007248. Mpv17_PMP22.
[Graphical view]
PANTHERiPTHR11266. PTHR11266. 1 hit.
PfamiPF04117. Mpv17_PMP22. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of a 36.2 kb fragment from the right arm of yeast chromosome XV reveals 19 open reading frames including SNF2 (5' end), CPA1, SLY41, a putative transport ATPase, a putative ribosomal protein and an SNF2 homologue."
    Poirey R., Cziepluch C., Tobiasch E., Pujol A., Kordes E., Jauniaux J.-C.
    Yeast 13:479-482(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV."
    Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J., Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A., Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B., Dang V.-D.
    , de Haan M., Delius H., Durand P., Fairhead C., Feldmann H., Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E., Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U., Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B., Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A., Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C., Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G., Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B., Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F., Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E., Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I., Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H., Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.
    Nature 387:98-102(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  5. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
    Kim H., Melen K., Oesterberg M., von Heijne G.
    Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: ATCC 208353 / W303-1A.
  6. "Global analysis of the glycoproteome in Saccharomyces cerevisiae reveals new roles for protein glycosylation in eukaryotes."
    Kung L.A., Tao S.-C., Qian J., Smith M.G., Snyder M., Zhu H.
    Mol. Syst. Biol. 5:308-308(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiYO292_YEAST
AccessioniPrimary (citable) accession number: Q08743
Secondary accession number(s): D6W2Z0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 10, 2006
Last sequence update: October 31, 1996
Last modified: January 6, 2015
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XV
    Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.