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Protein

Thiosulfate sulfurtransferase RDL2, mitochondrial

Gene

RDL2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Thiosulfate sulfurtransferase which catalyzes the transfer of sulfane sulfur from thiosulfate to cyanide.1 Publication

Miscellaneous

Present with 4220 molecules/cell in log phase SD medium.1 Publication

Catalytic activityi

Thiosulfate + cyanide = sulfite + thiocyanate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei106Cysteine persulfide intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

  • thiosulfate sulfurtransferase activity Source: SGD

Keywordsi

Molecular functionTransferase

Enzyme and pathway databases

BioCyciMetaCyc:G3O-33772-MONOMER
YEAST:G3O-33772-MONOMER
ReactomeiR-SCE-1614517 Sulfide oxidation to sulfate

Names & Taxonomyi

Protein namesi
Recommended name:
Thiosulfate sulfurtransferase RDL2, mitochondrial (EC:2.8.1.1)
Alternative name(s):
Altered inheritance of mitochondria protein 42
Found in mitochondrial proteome protein 31
Rhodanese-like protein 2
Gene namesi
Name:RDL2
Synonyms:AIM42, FMP31
Ordered Locus Names:YOR286W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XV

Organism-specific databases

EuPathDBiFungiDB:YOR286W
SGDiS000005812 RDL2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

Pathology & Biotechi

Disruption phenotypei

Increases frequency of mitochondrial genome loss.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 25MitochondrionSequence analysisAdd BLAST25
ChainiPRO_000024526826 – 149Thiosulfate sulfurtransferase RDL2, mitochondrialAdd BLAST124

Proteomic databases

MaxQBiQ08742
PaxDbiQ08742
PRIDEiQ08742

Interactioni

Protein-protein interaction databases

BioGridi34673, 57 interactors
DIPiDIP-4456N
IntActiQ08742, 1 interactor
STRINGi4932.YOR286W

Structurei

3D structure databases

ProteinModelPortaliQ08742
SMRiQ08742
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini45 – 146RhodanesePROSITE-ProRule annotationAdd BLAST102

Keywords - Domaini

Transit peptide

Phylogenomic databases

GeneTreeiENSGT00510000047949
InParanoidiQ08742
OMAiIFFCQMG
OrthoDBiEOG092C4WKM

Family and domain databases

Gene3Di3.40.250.10, 1 hit
InterProiView protein in InterPro
IPR001763 Rhodanese-like_dom
IPR036873 Rhodanese-like_dom_sf
PfamiView protein in Pfam
PF00581 Rhodanese, 1 hit
SMARTiView protein in SMART
SM00450 RHOD, 1 hit
SUPFAMiSSF52821 SSF52821, 1 hit
PROSITEiView protein in PROSITE
PS50206 RHODANESE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q08742-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFKHSTGILS RTVSARSPTL VLRTFTTKAP KIYTFDQVRN LVEHPNDKKL
60 70 80 90 100
LVDVREPKEV KDYKMPTTIN IPVNSAPGAL GLPEKEFHKV FQFAKPPHDK
110 120 130 140
ELIFLCAKGV RAKTAEELAR SYGYENTGIY PGSITEWLAK GGADVKPKK
Length:149
Mass (Da):16,697
Last modified:November 1, 1996 - v1
Checksum:i8BF91B05233CB81F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z75194 Genomic DNA Translation: CAA99513.1
AY692684 Genomic DNA Translation: AAT92703.1
BK006948 Genomic DNA Translation: DAA11050.1
PIRiS67188
RefSeqiNP_014929.3, NM_001183705.3

Genome annotation databases

EnsemblFungiiYOR286W; YOR286W; YOR286W
GeneIDi854460
KEGGisce:YOR286W

Similar proteinsi

Entry informationi

Entry nameiRDL2_YEAST
AccessioniPrimary (citable) accession number: Q08742
Secondary accession number(s): D6W2Y4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2006
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XV
    Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names

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