Reviewed, UniProtKB/Swiss-Prot Q08742 (FMP31_YEAST)

Names and origin

Protein names

Recommended name:
    Putative thiosulfate sulfurtransferase FMP31, mitochondrial
    EC=2.8.1.1
Alternative name(s):
    Found in mitochondrial proteome protein 31

Gene names

Name:	FMP31
Ordered Locus Names:	YOR286W

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	149 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	Thiosulfate + cyanide = sulfite + thiocyanate.
Subcellular location	Mitochondrion. Ref.3 Ref.5
Miscellaneous	Present with 4220 molecules/cell in log phase SD medium. Ref.4
Sequence similarities	Contains 1 rhodanese domain.

Ontologies

Keywords
Cellular component	Mitochondrion
Domain	Transit peptide
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	mitochondrion Ref.3 Ref.5 Inferred from direct assay. Source: SGD
Molecular function	protein binding Inferred from physical interaction. Source: IntAct thiosulfate sulfurtransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
PFK1	P16861	1	EBI-33610,EBI-9428

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – 25	25	Mitochondrion Potential
	Chain	26 – 149	124	Putative thiosulfate sulfurtransferase FMP31, mitochondrial		PRO_0000245268
Regions
	Domain	45 – 146	102	Rhodanese
Sites
	Active site	106	1	Cysteine persulfide intermediate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q08742-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 8BF91B05233CB81F	FASTA	149	16,697
	10 20 30 40 50 60 MFKHSTGILS RTVSARSPTL VLRTFTTKAP KIYTFDQVRN LVEHPNDKKL LVDVREPKEV 70 80 90 100 110 120 KDYKMPTTIN IPVNSAPGAL GLPEKEFHKV FQFAKPPHDK ELIFLCAKGV RAKTAEELAR 130 140 SYGYENTGIY PGSITEWLAK GGADVKPKK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XV." Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J., Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A., Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B., Dang V.-D. , de Haan M., Delius H., Durand P., Fairhead C., Feldmann H., Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E., Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U., Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B., Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A., Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C., Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G., Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B., Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F., Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E., Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I., Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H., Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K. Nature 387:98-102(1997) [PubMed: 9169874] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[2]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[3]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed: 14562095] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[4]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[5]	"The proteome of Saccharomyces cerevisiae mitochondria." Sickmann A., Reinders J., Wagner Y., Joppich C., Zahedi R.P., Meyer H.E., Schoenfisch B., Perschil I., Chacinska A., Guiard B., Rehling P., Pfanner N., Meisinger C. Proc. Natl. Acad. Sci. U.S.A. 100:13207-13212(2003) [PubMed: 14576278] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	Z75194 Genomic DNA. Translation: CAA99513.1. AY692684 Genomic DNA. Translation: AAT92703.1.
PIR	S67188.
RefSeq	NP_014929.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:4456N.
IntAct	Q08742. 2 interactions.
STRING	Q08742.
Proteomic databases
PeptideAtlas	Q08742.
Genome annotation databases
Ensembl	YOR286W; YOR286W; YOR286W; Saccharomyces cerevisiae. [Genome view]
GeneID	854460.
GenomeReviews	Gene locus YOR286W in contig Y13140_GR.
KEGG	sce:YOR286W.
NMPDR	fig|4932.3.peg.6041.
Organism-specific databases
CYGD	YOR286w.
SGD	S000005812. FMP31.
Phylogenomic databases
HOGENOM	Q08742.
OMA	AVNISIT.
Enzyme and pathway databases
BioCyc	MetaCyc:MON-12520.
BRENDA	2.8.1.1. 250.
Gene expression databases
ArrayExpress	Q08742.
Genevestigator	Q08742.
GermOnline	YOR286W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR001763. Rhodanese-like. [Graphical view]
Gene3D	G3DSA:3.40.250.10. Rhodanese-like. 1 hit.
Pfam	PF00581. Rhodanese. 1 hit. [Graphical view]
SMART	SM00450. RHOD. 1 hit. [Graphical view]
PROSITE	PS50206. RHODANESE_3. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	976736.

Entry information

Entry name

FMP31_YEAST

Accession

Primary (citable) accession number: Q08742

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 11, 2006
Last sequence update:	November 1, 1996
Last modified:	November 3, 2009
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)