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Q086G0 (DEOC_SHEFN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Deoxyribose-phosphate aldolase
Short name=DERA
EC=4.1.2.4
Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolase
Phosphodeoxyriboaldolase
Short name=Deoxyriboaldolase
Gene names
Name:deoC
Ordered Locus Names:Sfri_1002
OrganismShewanella frigidimarina (strain NCIMB 400) [Complete proteome] [HAMAP]
Taxonomic identifier318167 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length257 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate By similarity. HAMAP MF_00592

Catalytic activity

2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00592

Pathway

Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00592

Subcellular location

Cytoplasm By similarity HAMAP MF_00592.

Sequence similarities

Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandSchiff base
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processdeoxyribonucleotide catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiondeoxyribose-phosphate aldolase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 257257Deoxyribose-phosphate aldolase HAMAP MF_00592
PRO_1000072605

Sites

Active site1661Schiff-base intermediate with acetaldehyde By similarity
Active site1981 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q086G0 [UniParc].

Last modified October 31, 2006. Version 1.
Checksum: 63CAC33444EE64E8

FASTA25727,669
        10         20         30         40         50         60 
MTDLKKAAQR GIELMDLTTL NDDDTDQKVI DLCHKAKSPA GNTAAICIYP RFIPIARKTL 

        70         80         90        100        110        120 
NELDCEDIKI ATVTNFPHGN DDIAIAVLET RAAVAYGADE VDVVFPYRAL MDGNETVGFE 

       130        140        150        160        170        180 
MVKACKEECG DDAILKVIIE SGVLKDPALI RKASELAIDA GADFIKTSTG KVPVNATLEA 

       190        200        210        220        230        240 
AEIMLTVISE KNRNVGFKPA GGVRDAAQTA EFLDLAARIL GDDWVTPQTF RFGASSLLNS 

       250 
LLHTLELVDA PKPTSGY

« Hide

References

[1]"Complete sequence of Shewanella frigidimarina NCIMB 400."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Fredrickson J.K., Kolker E., McCuel L.A., DiChristina T., Nealson K.H., Newman D., Tiedje J.M. expand/collapse author list , Zhou J., Romine M.F., Culley D.E., Serres M., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NCIMB 400.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000447 Genomic DNA. Translation: ABI70855.1.
RefSeqYP_749693.1. NC_008345.1.

3D structure databases

ProteinModelPortalQ086G0.
SMRQ086G0. Positions 1-233.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ086G0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4278376.
GenomeReviewsGene locus Sfri_1002 in contig CP000447_GR.
KEGGsfr:Sfri_1002.
NMPDRfig|318167.10.peg.954.
PATRIC23495859. VBISheFri14343_1036.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0274.
HOGENOMHBG636421.
OMAELVQQCK.
PhylomeDBQ086G0.
ProtClustDBPRK05283.

Family and domain databases

HAMAPMF_00592. DeoC_type2.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR011343. DeoC.
IPR002915. DeoC/AroFGH_arch.
IPR023649. DeoC_bac.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01619.
PANTHERPTHR10889. DeoC. 1 hit.
PfamPF01791. DeoC. 1 hit.
[Graphical view]
PIRSFPIRSF001357. DeoC. 1 hit.
TIGRFAMsTIGR00126. DeoC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDEOC_SHEFN
AccessionPrimary (citable) accession number: Q086G0
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: October 31, 2006
Last modified: January 25, 2012
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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