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Q08682

- RSSA1_ARATH

UniProt

Q08682 - RSSA1_ARATH

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Protein

40S ribosomal protein Sa-1

Gene
RPSaA, At1g72370, T10D10.16
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits By similarity.UniRule annotation

GO - Molecular functioni

  1. structural constituent of ribosome Source: RefGenome

GO - Biological processi

  1. endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: RefGenome
  2. endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: RefGenome
  3. response to osmotic stress Source: TAIR
  4. response to salt stress Source: TAIR
  5. ribosomal small subunit assembly Source: RefGenome
  6. rRNA export from nucleus Source: RefGenome
  7. translation Source: RefGenome
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiREACT_187631. SRP-dependent cotranslational protein targeting to membrane.
REACT_187829. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
REACT_190931. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein Sa-1
Alternative name(s):
Laminin receptor homolog
p40
Gene namesi
Name:RPSaA
Ordered Locus Names:At1g72370
ORF Names:T10D10.16
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 1

Organism-specific databases

TAIRiAT1G72370.

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. 90S preribosome Source: RefGenome
  2. chloroplast Source: TAIR
  3. cytoplasm Source: TAIR
  4. cytosol Source: TAIR
  5. cytosolic ribosome Source: TAIR
  6. cytosolic small ribosomal subunit Source: TAIR
  7. membrane Source: TAIR
  8. nucleus Source: TAIR
  9. plasma membrane Source: TAIR
  10. plasmodesma Source: TAIR
  11. small ribosomal subunit Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed1 Publication
Chaini2 – 29829740S ribosomal protein Sa-1UniRule annotationPRO_0000134346Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanine1 Publication

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ08682.
PRIDEiQ08682.

Expressioni

Gene expression databases

ArrayExpressiQ08682.
GenevestigatoriQ08682.

Interactioni

Subunit structurei

Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with ribosomal protein S21 By similarity.

Protein-protein interaction databases

BioGridi28789. 5 interactions.
IntActiQ08682. 2 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ08682.
SMRiQ08682. Positions 12-197.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi247 – 29852Ala/Pro-richUniRule annotationAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0052.
HOGENOMiHOG000232073.
InParanoidiQ08682.
KOiK02998.
OMAiPIMEASY.
PhylomeDBiQ08682.

Family and domain databases

HAMAPiMF_03015. Ribosomal_S2_euk.
InterProiIPR001865. Ribosomal_S2.
IPR018130. Ribosomal_S2_CS.
IPR027498. Ribosomal_S2_euk.
IPR005707. Ribosomal_S2_euk/arc.
IPR023591. Ribosomal_S2_flav_dom.
[Graphical view]
PANTHERiPTHR11489. PTHR11489. 1 hit.
PfamiPF00318. Ribosomal_S2. 2 hits.
[Graphical view]
PRINTSiPR00395. RIBOSOMALS2.
SUPFAMiSSF52313. SSF52313. 1 hit.
TIGRFAMsiTIGR01012. Sa_S2_E_A. 1 hit.
PROSITEiPS00962. RIBOSOMAL_S2_1. 1 hit.
PS00963. RIBOSOMAL_S2_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 1 isoform i produced by alternative splicing. Align

Note: A number of isoforms are produced. According to EST sequences.

Isoform 1 (identifier: Q08682-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MATNGSASSA QLSQKEADVR MMCAAEVHLG TKNCNYQMER YVFKRRNDGI    50
YIFNLGKTWE KLQMAARVIV AIENPQDIIV QSARPYGQRA VLKFAQYTGA 100
NAIAGRHTPG TFTNQMQTSF SEPRLLILTD PRTDHQPIKE GALGNIPIIA 150
FCDTDSPMRF VDIGIPANNK GKHSIGCLFW LLARMVLQMR GTIAAGQKWD 200
VMVDLFFYRE PEETKPEDED EAGPQAEYGA LPAPEYGMVG GDQWTTAQIP 250
DAAWPGEGQA PISAAPAAAS WSDSAAAPAD GGWEAAAPPS GAPAAGWE 298
Length:298
Mass (Da):32,291
Last modified:August 30, 2005 - v3
Checksum:iE5C1A846A30161B6
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti11 – 122QL → HV1 Publication
Sequence conflicti11 – 122QL → HV1 Publication
Sequence conflicti11 – 122QL → HV1 Publication
Sequence conflicti211 – 2111P → L in CAA48794. 1 Publication
Sequence conflicti212 – 2132EE → DY1 Publication
Sequence conflicti212 – 2132EE → DY1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X69056 mRNA. Translation: CAA48794.1.
U01955 mRNA. Translation: AAA53425.1.
X89366 Genomic DNA. Translation: CAA61547.1.
Y10379 Genomic DNA. Translation: CAA71407.1.
AC016529 Genomic DNA. Translation: AAG52587.1.
CP002684 Genomic DNA. Translation: AEE35313.1.
AY054211 mRNA. Translation: AAL06872.1.
AY058885 mRNA. Translation: AAL24271.1.
AY065096 mRNA. Translation: AAL38272.1.
AY079041 mRNA. Translation: AAL79591.1.
AY114561 mRNA. Translation: AAM47880.1.
AY136324 mRNA. Translation: AAM96990.1.
BT000421 mRNA. Translation: AAN15740.1.
AY087976 mRNA. Translation: AAM65523.1.
PIRiF96747.
S71247.
RefSeqiNP_177381.1. NM_105896.3. [Q08682-1]
UniGeneiAt.22576.
At.35111.
At.70162.

Genome annotation databases

EnsemblPlantsiAT1G72370.1; AT1G72370.1; AT1G72370. [Q08682-1]
GeneIDi843569.
KEGGiath:AT1G72370.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X69056 mRNA. Translation: CAA48794.1 .
U01955 mRNA. Translation: AAA53425.1 .
X89366 Genomic DNA. Translation: CAA61547.1 .
Y10379 Genomic DNA. Translation: CAA71407.1 .
AC016529 Genomic DNA. Translation: AAG52587.1 .
CP002684 Genomic DNA. Translation: AEE35313.1 .
AY054211 mRNA. Translation: AAL06872.1 .
AY058885 mRNA. Translation: AAL24271.1 .
AY065096 mRNA. Translation: AAL38272.1 .
AY079041 mRNA. Translation: AAL79591.1 .
AY114561 mRNA. Translation: AAM47880.1 .
AY136324 mRNA. Translation: AAM96990.1 .
BT000421 mRNA. Translation: AAN15740.1 .
AY087976 mRNA. Translation: AAM65523.1 .
PIRi F96747.
S71247.
RefSeqi NP_177381.1. NM_105896.3. [Q08682-1 ]
UniGenei At.22576.
At.35111.
At.70162.

3D structure databases

ProteinModelPortali Q08682.
SMRi Q08682. Positions 12-197.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 28789. 5 interactions.
IntActi Q08682. 2 interactions.

Proteomic databases

PaxDbi Q08682.
PRIDEi Q08682.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT1G72370.1 ; AT1G72370.1 ; AT1G72370 . [Q08682-1 ]
GeneIDi 843569.
KEGGi ath:AT1G72370.

Organism-specific databases

GeneFarmi 5044.
TAIRi AT1G72370.

Phylogenomic databases

eggNOGi COG0052.
HOGENOMi HOG000232073.
InParanoidi Q08682.
KOi K02998.
OMAi PIMEASY.
PhylomeDBi Q08682.

Enzyme and pathway databases

Reactomei REACT_187631. SRP-dependent cotranslational protein targeting to membrane.
REACT_187829. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
REACT_190931. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).

Gene expression databases

ArrayExpressi Q08682.
Genevestigatori Q08682.

Family and domain databases

HAMAPi MF_03015. Ribosomal_S2_euk.
InterProi IPR001865. Ribosomal_S2.
IPR018130. Ribosomal_S2_CS.
IPR027498. Ribosomal_S2_euk.
IPR005707. Ribosomal_S2_euk/arc.
IPR023591. Ribosomal_S2_flav_dom.
[Graphical view ]
PANTHERi PTHR11489. PTHR11489. 1 hit.
Pfami PF00318. Ribosomal_S2. 2 hits.
[Graphical view ]
PRINTSi PR00395. RIBOSOMALS2.
SUPFAMi SSF52313. SSF52313. 1 hit.
TIGRFAMsi TIGR01012. Sa_S2_E_A. 1 hit.
PROSITEi PS00962. RIBOSOMAL_S2_1. 1 hit.
PS00963. RIBOSOMAL_S2_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "An Arabidopsis cDNA encoding a 33-kilodalton laminin receptor homolog."
    Axelos M., Bardet C., Lescure B.
    Plant Physiol. 103:299-300(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Columbia.
  2. "Arabidopsis p40 homologue. A novel acidic protein associated with the 40 S subunit of ribosomes."
    Garcia-Hernandez M., Davies E., Staswick P.E.
    J. Biol. Chem. 269:20744-20749(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Columbia.
    Tissue: Leaf.
  3. "Characterization of a ribosomal p40 homologue gene showing the same pattern of expression as the elongation factor-1 alpha in Arabidopsis thaliana."
    Scheer I., Axelos M., Pont-Lezica R.F.
    Plant Physiol. Biochem. 34:501-508(1996)
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: cv. Columbia.
  4. "Expression of a gene encoding a ribosomal p40 protein and identification of an active promoter site."
    Scheer I., Ludevid M.D., Regad F.F., Lescure B., Pont-Lezica R.F.
    Plant Mol. Biol. 35:905-913(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: cv. Columbia.
  5. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  6. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  7. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  8. "Full-length cDNA from Arabidopsis thaliana."
    Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
    Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  9. "The organization of cytoplasmic ribosomal protein genes in the Arabidopsis genome."
    Barakat A., Szick-Miranda K., Chang I.-F., Guyot R., Blanc G., Cooke R., Delseny M., Bailey-Serres J.
    Plant Physiol. 127:398-415(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY ORGANIZATION, NOMENCLATURE.
  10. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
    Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T., Giglione C.
    Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiRSSA1_ARATH
AccessioniPrimary (citable) accession number: Q08682
Secondary accession number(s): Q93V81
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: August 30, 2005
Last modified: September 3, 2014
This is version 112 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Caution

Was originally thought to be a laminin receptor.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi