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Q08637 (NTPB_ENTHA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
V-type sodium ATPase subunit B
Alternative name(s):
Na(+)-translocating ATPase subunit B
V-type sodium pump subunit B
Gene names
Name:ntpB
Ordered Locus Names:EHR_08265
OrganismEnterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258) [Complete proteome] [HAMAP]
Taxonomic identifier768486 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeEnterococcus

Protein attributes

Sequence length458 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Involved in ATP-driven sodium extrusion. HAMAP-Rule MF_00310

Induction

By increasing intracellular Na+ concentration. HAMAP-Rule MF_00310

Sequence similarities

Belongs to the ATPase alpha/beta chains family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 458458V-type sodium ATPase subunit B HAMAP-Rule MF_00310
PRO_0000144685

Secondary structure

.................................................................................. 458
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q08637 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: D89D8F2F58B65262

FASTA45851,142
        10         20         30         40         50         60 
MIKEYRTIKE VVGPLMAVEK VSGVKYEELI EVRMQNGEIR RGQVLEVQED KAMVQIFEGT 

        70         80         90        100        110        120 
SGINLKNSSV RFLGHPLQLG VSEDMIGRVF DGLGRPKDNG PEILPEKYLD INGEVINPIA 

       130        140        150        160        170        180 
RDYPDEFIQT GISAIDHLNT LVRGQKLPVF SGSGLPHKEL AAQIARQATV LDSSDDFAVV 

       190        200        210        220        230        240 
FAAIGITFEE AEFFMEDFRQ TGAIDRSVMF MNLANDPAIE RIATPRMALT AAEYLAYEKG 

       250        260        270        280        290        300 
MHVLVIMTDM TNYAEALREI SAARREVPGR RGYPGYLYTN LATLFERAGR IRGLKGSVTQ 

       310        320        330        340        350        360 
IPILTMPEDD KTHPIPDLTG YITEGQIILT RELYKSGIQP PIDVLPSLSR LKDKGTGAGK 

       370        380        390        400        410        420 
TREDHAATMN QLFAAYAQGK QAKELAVVLG ESALSDIDKI YAKFAERFEN EYVNQGFYTN 

       430        440        450 
RTITETLDLG WELLAMLPRT ELKRIKDDLL DKYLPEGK 

« Hide

References

« Hide 'large scale' references
[1]"Cloning and sequencing of the genes coding for the A and B subunits of vacuolar-type Na(+)-ATPase from Enterococcus hirae. Coexistence of vacuolar- and F0F1-type ATPases in one bacterial cell."
Takase K., Yamato I., Kakinuma Y.
J. Biol. Chem. 268:11610-11616(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 1-25.
Strain: ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258.
[2]"Genome sequence of Enterococcus hirae (Streptococcus faecalis) ATCC 9790, a model organism for the study of ion transport, bioenergetics, and copper homeostasis."
Gaechter T., Wunderlin C., Schmidheini T., Solioz M.
J. Bacteriol. 194:5126-5127(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D13816 Genomic DNA. Translation: BAA02970.1.
D17462 Genomic DNA. Translation: BAA04276.1.
CP003504 Genomic DNA. Translation: AFM70580.1.
PIRB46733.
RefSeqYP_006487471.1. NC_018081.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3VR2X-ray2.80D/E/F1-458[»]
3VR3X-ray3.40D/E/F1-458[»]
3VR4X-ray2.17D/E/F1-458[»]
3VR5X-ray3.90D/E/F1-458[»]
3VR6X-ray2.68D/E/F1-458[»]
ProteinModelPortalQ08637.
SMRQ08637. Positions 13-456.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-60126N.

Protein family/group databases

TCDB3.A.2.2.2. the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFM70580; AFM70580; EHR_08265.
GeneID13177594.
KEGGehr:EHR_08265.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK02118.

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-14147.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00310. ATP_synth_B_arch.
InterProIPR020003. ATPase_a/bsu_AS.
IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
IPR004100. ATPase_F1_a/bsu_N.
IPR027417. P-loop_NTPase.
IPR022879. V-ATPase_su_B/beta.
[Graphical view]
PfamPF00006. ATP-synt_ab. 1 hit.
PF00306. ATP-synt_ab_C. 1 hit.
PF02874. ATP-synt_ab_N. 1 hit.
[Graphical view]
SUPFAMSSF47917. SSF47917. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEPS00152. ATPASE_ALPHA_BETA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNTPB_ENTHA
AccessionPrimary (citable) accession number: Q08637
Secondary accession number(s): I6S1L8
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: April 16, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references