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Protein

V-type sodium ATPase subunit B

Gene

ntpB

Organism
Enterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Involved in ATP-driven sodium extrusion.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Ion transport, Sodium transport, Transport

Keywords - Ligandi

Sodium

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-14147.

Protein family/group databases

TCDBi3.A.2.2.2. the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
V-type sodium ATPase subunit B
Alternative name(s):
Na(+)-translocating ATPase subunit B
V-type sodium pump subunit B
Gene namesi
Name:ntpB
Ordered Locus Names:EHR_08265
OrganismiEnterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258)
Taxonomic identifieri768486 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeEnterococcus
Proteomesi
  • UP000002895 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001446851 – 458V-type sodium ATPase subunit BAdd BLAST458

Proteomic databases

PRIDEiQ08637.

Expressioni

Inductioni

By increasing intracellular Na+ concentration.

Interactioni

Protein-protein interaction databases

DIPiDIP-60126N.

Structurei

Secondary structure

1458
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi8 – 12Combined sources5
Beta strandi15 – 20Combined sources6
Beta strandi29 – 33Combined sources5
Beta strandi39 – 56Combined sources18
Turni65 – 67Combined sources3
Beta strandi69 – 72Combined sources4
Beta strandi78 – 81Combined sources4
Helixi83 – 85Combined sources3
Beta strandi88 – 91Combined sources4
Beta strandi96 – 98Combined sources3
Beta strandi106 – 112Combined sources7
Turni118 – 120Combined sources3
Beta strandi127 – 129Combined sources3
Helixi133 – 136Combined sources4
Turni137 – 139Combined sources3
Beta strandi149 – 151Combined sources3
Helixi157 – 167Combined sources11
Beta strandi169 – 173Combined sources5
Beta strandi177 – 186Combined sources10
Helixi188 – 201Combined sources14
Helixi203 – 206Combined sources4
Beta strandi207 – 213Combined sources7
Helixi218 – 237Combined sources20
Beta strandi242 – 248Combined sources7
Helixi250 – 263Combined sources14
Helixi270 – 272Combined sources3
Helixi277 – 285Combined sources9
Beta strandi289 – 291Combined sources3
Beta strandi297 – 305Combined sources9
Helixi307 – 309Combined sources3
Helixi314 – 322Combined sources9
Beta strandi323 – 329Combined sources7
Helixi331 – 335Combined sources5
Turni344 – 346Combined sources3
Helixi352 – 354Combined sources3
Turni358 – 360Combined sources3
Helixi365 – 389Combined sources25
Helixi391 – 393Combined sources3
Helixi396 – 411Combined sources16
Helixi423 – 434Combined sources12
Turni439 – 441Combined sources3
Helixi447 – 453Combined sources7

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3VR2X-ray2.80D/E/F1-458[»]
3VR3X-ray3.40D/E/F1-458[»]
3VR4X-ray2.17D/E/F1-458[»]
3VR5X-ray3.90D/E/F1-458[»]
3VR6X-ray2.68D/E/F1-458[»]
ProteinModelPortaliQ08637.
SMRiQ08637.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATPase alpha/beta chains family.Curated

Phylogenomic databases

KOiK02118.
OrthoDBiPOG091H03NZ.

Family and domain databases

Gene3Di1.10.1140.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00310. ATP_synth_B_arch. 1 hit.
InterProiIPR020003. ATPase_a/bsu_AS.
IPR004100. ATPase_F1/V1/A1_a/bsu_N.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
IPR024034. ATPase_F1/V1_bsu_C.
IPR027417. P-loop_NTPase.
IPR022879. V-ATPase_su_B/beta.
[Graphical view]
PfamiPF00006. ATP-synt_ab. 1 hit.
PF02874. ATP-synt_ab_N. 1 hit.
[Graphical view]
PIRSFiPIRSF039114. V-ATPsynth_beta/V-ATPase_B. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00152. ATPASE_ALPHA_BETA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q08637-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKEYRTIKE VVGPLMAVEK VSGVKYEELI EVRMQNGEIR RGQVLEVQED
60 70 80 90 100
KAMVQIFEGT SGINLKNSSV RFLGHPLQLG VSEDMIGRVF DGLGRPKDNG
110 120 130 140 150
PEILPEKYLD INGEVINPIA RDYPDEFIQT GISAIDHLNT LVRGQKLPVF
160 170 180 190 200
SGSGLPHKEL AAQIARQATV LDSSDDFAVV FAAIGITFEE AEFFMEDFRQ
210 220 230 240 250
TGAIDRSVMF MNLANDPAIE RIATPRMALT AAEYLAYEKG MHVLVIMTDM
260 270 280 290 300
TNYAEALREI SAARREVPGR RGYPGYLYTN LATLFERAGR IRGLKGSVTQ
310 320 330 340 350
IPILTMPEDD KTHPIPDLTG YITEGQIILT RELYKSGIQP PIDVLPSLSR
360 370 380 390 400
LKDKGTGAGK TREDHAATMN QLFAAYAQGK QAKELAVVLG ESALSDIDKI
410 420 430 440 450
YAKFAERFEN EYVNQGFYTN RTITETLDLG WELLAMLPRT ELKRIKDDLL

DKYLPEGK
Length:458
Mass (Da):51,142
Last modified:November 1, 1995 - v1
Checksum:iD89D8F2F58B65262
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D13816 Genomic DNA. Translation: BAA02970.1.
D17462 Genomic DNA. Translation: BAA04276.1.
CP003504 Genomic DNA. Translation: AFM70580.1.
PIRiB46733.
RefSeqiWP_010718636.1. NZ_KB946231.1.

Genome annotation databases

EnsemblBacteriaiAFM70580; AFM70580; EHR_08265.
GeneIDi13177594.
KEGGiehr:EHR_08265.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D13816 Genomic DNA. Translation: BAA02970.1.
D17462 Genomic DNA. Translation: BAA04276.1.
CP003504 Genomic DNA. Translation: AFM70580.1.
PIRiB46733.
RefSeqiWP_010718636.1. NZ_KB946231.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3VR2X-ray2.80D/E/F1-458[»]
3VR3X-ray3.40D/E/F1-458[»]
3VR4X-ray2.17D/E/F1-458[»]
3VR5X-ray3.90D/E/F1-458[»]
3VR6X-ray2.68D/E/F1-458[»]
ProteinModelPortaliQ08637.
SMRiQ08637.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-60126N.

Protein family/group databases

TCDBi3.A.2.2.2. the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily.

Proteomic databases

PRIDEiQ08637.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFM70580; AFM70580; EHR_08265.
GeneIDi13177594.
KEGGiehr:EHR_08265.

Phylogenomic databases

KOiK02118.
OrthoDBiPOG091H03NZ.

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-14147.

Family and domain databases

Gene3Di1.10.1140.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00310. ATP_synth_B_arch. 1 hit.
InterProiIPR020003. ATPase_a/bsu_AS.
IPR004100. ATPase_F1/V1/A1_a/bsu_N.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
IPR024034. ATPase_F1/V1_bsu_C.
IPR027417. P-loop_NTPase.
IPR022879. V-ATPase_su_B/beta.
[Graphical view]
PfamiPF00006. ATP-synt_ab. 1 hit.
PF02874. ATP-synt_ab_N. 1 hit.
[Graphical view]
PIRSFiPIRSF039114. V-ATPsynth_beta/V-ATPase_B. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00152. ATPASE_ALPHA_BETA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNTPB_ENTHA
AccessioniPrimary (citable) accession number: Q08637
Secondary accession number(s): I6S1L8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: November 30, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.