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Q08630 (IRC13_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative increased recombination centers protein 13
Gene names
Name:IRC13
Ordered Locus Names:YOR235W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length104 AA.
Sequence statusComplete.
Protein existenceUncertain

General annotation (Comments)

Function

May be involved in a pathway contributing to genomic integrity.

Subcellular location

Membrane; Single-pass membrane protein Potential.

Disruption phenotype

Displays increased levels of spontaneous RAD52 foci in proliferating diploid cells. Ref.3

Caution

Product of a dubious gene prediction. Partially overlaps small nucleolar RNA U3 (SNR17A).

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 104104Putative increased recombination centers protein 13
PRO_0000299728

Regions

Transmembrane63 – 8321Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q08630 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 14DC6770979382DF

FASTA10412,390
        10         20         30         40         50         60 
MGLYRPSKFF HPPIPHIPFT INPDFFSFHI QRLKAKANPE NFLICFPPPD IYKGFVFCCQ 

        70         80         90        100 
LDLVHLFSYV FFLFLLKICV DVLQYVIYPK HFTHKKPGFE NYSI 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XV."
Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J., Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A., Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B., Dang V.-D. expand/collapse author list , de Haan M., Delius H., Durand P., Fairhead C., Feldmann H., Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E., Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U., Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B., Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A., Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C., Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G., Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B., Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F., Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E., Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I., Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H., Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.
Nature 387:98-102(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination."
Alvaro D., Lisby M., Rothstein R.
PLoS Genet. 3:E228-E228(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: DISRUPTION PHENOTYPE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z75143 Genomic DNA. Translation: CAA99455.1.
Z75144 Genomic DNA. Translation: CAA99457.1.
BK006948 Genomic DNA. No translation available.
PIRS67128.

3D structure databases

ProteinModelPortalQ08630.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ08630. 1 interaction.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYOR235W; YOR235W; YOR235W.

Organism-specific databases

SGDS000005761. IRC13.

Phylogenomic databases

OrthoDBEOG7TN074.

Gene expression databases

GenevestigatorQ08630.

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameIRC13_YEAST
AccessionPrimary (citable) accession number: Q08630
Secondary accession number(s): O94149
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: November 1, 1996
Last modified: February 19, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XV

Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD