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Protein

Peroxisomal membrane protein PEX27

Gene

PEX27

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Required for regulation of peroxisome size and number. Also promotes peroxisome division and biogenesis.3 Publications

Miscellaneous

Present with 382 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

  • peroxisome fission Source: UniProtKB
  • peroxisome organization Source: SGD
  • regulation of peroxisome size Source: UniProtKB

Keywordsi

Biological processPeroxisome biogenesis

Enzyme and pathway databases

BioCyciYEAST:G3O-33702-MONOMER

Protein family/group databases

TCDBi1.A.101.7.3 the peroxisomal pore-forming pex11 (pex11) family
3.A.20.1.5 the peroxisomal protein importer (ppi) family

Names & Taxonomyi

Protein namesi
Recommended name:
Peroxisomal membrane protein PEX27
Alternative name(s):
Peroxin-27
Gene namesi
Name:PEX27
Ordered Locus Names:YOR193W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XV

Organism-specific databases

EuPathDBiFungiDB:YOR193W
SGDiS000005719 PEX27

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002705691 – 376Peroxisomal membrane protein PEX27Add BLAST376

Proteomic databases

MaxQBiQ08580
PaxDbiQ08580
PRIDEiQ08580

PTM databases

iPTMnetiQ08580

Interactioni

Subunit structurei

Homooligomer. Interacts with PEX25 and PEX34.3 Publications

Protein-protein interaction databases

BioGridi34591, 70 interactors
IntActiQ08580, 4 interactors
MINTiQ08580
STRINGi4932.YOR193W

Structurei

3D structure databases

ProteinModelPortaliQ08580
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi130 – 138Poly-Leu9

Phylogenomic databases

OrthoDBiEOG092C2X0R

Sequencei

Sequence statusi: Complete.

Q08580-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSDPVNTNI SSPTLTDRNA DESWELLKRE FNTLFSNLKT DSKEEGNFTD
60 70 80 90 100
NKGVIAKKPI VLQDNDDSDF TQNQGKVATA TSTTSDRSFK RTLGSIEMKK
110 120 130 140 150
RYVKKNCQAK FVFNTLEGKE VCSKILQHTL GLLSLLLLTR KIRLLNFSSK
160 170 180 190 200
LRLVIQQLSL FRYYLRFGNF AINLYKIIKR FRWLREMKKL HYKDQSILFY
210 220 230 240 250
FKNFRFFDII EAFYNLTDEL ILFHKLQSMF GKKNTSHANT NRLMTFVKEQ
260 270 280 290 300
HYILWEVLNI LAINKNIEQW RQLIRDEIYL SIYNTSGNAI KEYELKYKLP
310 320 330 340 350
TNDKVNLELR KNNITLDFYK IILNLLSNLI NIKGKRDKYN SELAYEIISV
360 370
GSGVTELLKL WNRAKVTSAN EHTSAV
Length:376
Mass (Da):44,131
Last modified:November 1, 1996 - v1
Checksum:i976FDBCA43AB4F80
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z75101 Genomic DNA Translation: CAA99406.1
AY723869 Genomic DNA Translation: AAU09786.1
BK006948 Genomic DNA Translation: DAA10968.1
PIRiS67085
RefSeqiNP_014836.3, NM_001183612.3

Genome annotation databases

EnsemblFungiiYOR193W; YOR193W; YOR193W
GeneIDi854368
KEGGisce:YOR193W

Similar proteinsi

Entry informationi

Entry nameiPEX27_YEAST
AccessioniPrimary (citable) accession number: Q08580
Secondary accession number(s): D6W2Q2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health